Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Daniel R. Schrider"'
Autor:
Andrew D. Kern, Daniel R. Schrider
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 6, Pp 1959-1970 (2018)
Identifying selective sweeps in populations that have complex demographic histories remains a difficult problem in population genetics. We previously introduced a supervised machine learning approach, S/HIC, for finding both hard and soft selective s
Externí odkaz:
https://doaj.org/article/c4f0b7986c554061a2314c81d69aa5c7
Autor:
Richard S. Fletcher, David Herrmann, Jack L. Mullen, Qinfei Li, Daniel R. Schrider, Nicholas Price, Junjiang Lin, Kelsi Grogan, Andrew Kern, John K. McKay
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 4, Pp 793-803 (2016)
Brassica napus is a globally important oilseed for which little is known about the genetics of drought adaptation. We previously mapped twelve quantitative trait loci (QTL) underlying drought-related traits in a biparental mapping population created
Externí odkaz:
https://doaj.org/article/4703844ca99b42d38e51e8f4b2b009b2
Autor:
Anton Suvorov, Daniel R Schrider
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 8, p e1012337 (2024)
A phylogenetic tree represents hypothesized evolutionary history for a set of taxa. Besides the branching patterns (i.e., tree topology), phylogenies contain information about the evolutionary distances (i.e. branch lengths) between all taxa in the t
Externí odkaz:
https://doaj.org/article/f20230af05dc4b65acc861414d4932aa
Publikováno v:
PLoS Genetics, Vol 20, Iss 2, p e1010657 (2024)
A growing body of evidence suggests that gene flow between closely related species is a widespread phenomenon. Alleles that introgress from one species into a close relative are typically neutral or deleterious, but sometimes confer a significant fit
Externí odkaz:
https://doaj.org/article/9e00471ac12c42a4aa4622a871c859df
Autor:
M Elise Lauterbur, Maria Izabel A Cavassim, Ariella L Gladstein, Graham Gower, Nathaniel S Pope, Georgia Tsambos, Jeffrey Adrion, Saurabh Belsare, Arjun Biddanda, Victoria Caudill, Jean Cury, Ignacio Echevarria, Benjamin C Haller, Ahmed R Hasan, Xin Huang, Leonardo Nicola Martin Iasi, Ekaterina Noskova, Jana Obsteter, Vitor Antonio Correa Pavinato, Alice Pearson, David Peede, Manolo F Perez, Murillo F Rodrigues, Chris CR Smith, Jeffrey P Spence, Anastasia Teterina, Silas Tittes, Per Unneberg, Juan Manuel Vazquez, Ryan K Waples, Anthony Wilder Wohns, Yan Wong, Franz Baumdicker, Reed A Cartwright, Gregor Gorjanc, Ryan N Gutenkunst, Jerome Kelleher, Andrew D Kern, Aaron P Ragsdale, Peter L Ralph, Daniel R Schrider, Ilan Gronau
Publikováno v:
eLife, Vol 12 (2023)
Simulation is a key tool in population genetics for both methods development and empirical research, but producing simulations that recapitulate the main features of genomic datasets remains a major obstacle. Today, more realistic simulations are pos
Externí odkaz:
https://doaj.org/article/ed75e3569fbf474782ef3b9546fe2394
Autor:
Jeffrey R Adrion, Christopher B Cole, Noah Dukler, Jared G Galloway, Ariella L Gladstein, Graham Gower, Christopher C Kyriazis, Aaron P Ragsdale, Georgia Tsambos, Franz Baumdicker, Jedidiah Carlson, Reed A Cartwright, Arun Durvasula, Ilan Gronau, Bernard Y Kim, Patrick McKenzie, Philipp W Messer, Ekaterina Noskova, Diego Ortega-Del Vecchyo, Fernando Racimo, Travis J Struck, Simon Gravel, Ryan N Gutenkunst, Kirk E Lohmueller, Peter L Ralph, Daniel R Schrider, Adam Siepel, Jerome Kelleher, Andrew D Kern
Publikováno v:
eLife, Vol 9 (2020)
The explosion in population genomic data demands ever more complex modes of analysis, and increasingly, these analyses depend on sophisticated simulations. Recent advances in population genetic simulation have made it possible to simulate large and c
Externí odkaz:
https://doaj.org/article/3524c850e8cf4035a0c097b7202a542b
Autor:
Quan Sun, Yingxi Yang, Jonathan D. Rosen, Min-Zhi Jiang, Jiawen Chen, Weifang Liu, Jia Wen, Laura M. Raffield, Rhonda G. Pace, Yi-Hui Zhou, Fred A. Wright, Scott M. Blackman, Michael J. Bamshad, Ronald L. Gibson, Garry R. Cutting, Michael R. Knowles, Daniel R. Schrider, Christian Fuchsberger, Yun Li
Publikováno v:
The American Journal of Human Genetics. 109:1986-1997
Whole-genome sequencing (WGS) is the gold standard for fully characterizing genetic variation but is still prohibitively expensive for large samples. To reduce costs, many studies sequence only a subset of individuals or genomic regions, and genotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4d816b50df519646c97ca65c9e218c
https://doi.org/10.1016/j.ajhg.2022.09.009
https://doi.org/10.1016/j.ajhg.2022.09.009
Publikováno v:
GENETICS. 224
Numerous studies over the last decade have demonstrated the utility of machine learning methods when applied to population genetic tasks. More recent studies show the potential of deep-learning methods in particular, which allow researchers to approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a93970b1cbbab6d2bb73cc6baef78f9
https://doi.org/10.1093/genetics/iyad063
https://doi.org/10.1093/genetics/iyad063
Publikováno v:
Molecular Biology and Evolution. 40
Aedes aegypti vectors the pathogens that cause dengue, yellow fever, Zika virus, and chikungunya, and is a serious threat to public health in tropical regions. Decades of work has illuminated many aspects of Ae. aegypti’s biology and global populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367d2f986a96d3109f1fddfceff5ac8c
https://doi.org/10.1093/molbev/msad072
https://doi.org/10.1093/molbev/msad072
1AbstractA growing body of evidence suggests that gene flow between closely related species is a widespread phenomenon. Alleles that introgress from one species into a close relative are typically neutral or deleterious, but sometimes confer a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49bb5610f6efc44dfb342c54a2a86330
https://doi.org/10.1101/2023.02.07.527435
https://doi.org/10.1101/2023.02.07.527435
