Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Daniel R. Raymond"'
1
Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion
Autor: Daniel R. Raymond, Rhonda L. Carter, Donald H. Maurice, Lindsay S. Wilson
Publikováno v: Cellular Signalling. 19:2507-2518
By activating two distinct classes of effector enzymes, namely Protein Kinases A [PKA] or E xchange P roteins A ctivated by c AMP [EPAC], the ubiquitous second messenger cAMP selectively coordinates numerous events simultaneously in virtually all cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d8ad1d5b82f6fd49f39415c1044f53
https://doi.org/10.1016/j.cellsig.2007.08.005
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2
Altered Phosphodiesterase 3-Mediated cAMP Hydrolysis Contributes to a Hypermotile Phenotype in Obese JCR:LA-cp Rat Aortic Vascular Smooth Muscle Cells
Autor: Douglas G. Tilley, Donald H. Maurice, P. Marlene Absher, Heather A. Dunkerley, Daniel R. Raymond, Robert B. Vernon, Stuart J. Netherton, Daniel Palmer, Sandra L. Jimmo, E. Helene Sage, James C. Russell
Publikováno v: Diabetes. 51:1194-1200
Cardiovascular diseases represent a significant cause of morbidity and mortality in diabetes. Of the many animal models used in the study of non-insulin-dependent (type 2) diabetes, the JCR:LA-cp rat is unique in that it develops insulin resistance i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf03f37af5cd07a10ed945b9d8a6b080
https://doi.org/10.2337/diabetes.51.4.1194
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3
Distinct phosphodiesterase-4D variants integrate into protein kinase A-based signaling complexes in cardiac and vascular myocytes
Autor: Christopher A. Ward, Donald H. Maurice, Rhonda L. Carter, Daniel R. Raymond
Publikováno v: American journal of physiology. Heart and circulatory physiology. 296(2)
Numerous cAMP-elevating agents regulate events required for efficient migration of arterial vascular smooth muscle cells (VSMCs). Interestingly, when the impact of cAMP-elevating agents on individual migration-related events is studied, these agents
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3c323d17189cd4ef9e2d845ab946b7
https://pubmed.ncbi.nlm.nih.gov/19060129
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4
Protein kinase A phosphorylation of human phosphodiesterase 3B promotes 14-3-3 protein binding and inhibits phosphatase-catalyzed inactivation
Autor: Daniel Palmer, Sandra L. Jimmo, Donald H. Maurice, Lindsay S. Wilson, Rhonda L. Carter, Daniel R. Raymond
Publikováno v: The Journal of biological chemistry. 282(13)
Recent studies confirm that intracellular cAMP concentrations are nonuniform and that localized subcellular cAMP hydrolysis by cyclic nucleotide phosphodiesterases (PDEs) is important in maintaining these cAMP compartments. Human phosphodiesterase 3B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306dfd3ea0a1aae75f93515ceb1ccd9e
https://pubmed.ncbi.nlm.nih.gov/17255105
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5
Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system
Autor: Donald H. Maurice, Stuart J. Netherton, Douglas G. Tilley, Heather A. Dunkerley, Sandra L. Jimmo, Hisham S. Elbatarny, Daniel Palmer, Daniel R. Raymond
Publikováno v: Molecular pharmacology. 64(3)
Cyclic AMP (cAMP) and cGMP regulate a myriad of cellular functions, such as metabolism, contractility, motility, and transcription in virtually all cell types, including those of the cardiovascular system. Considerable effort over the last 20 years h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06dff8bf3715869067b7004c350e90f
https://pubmed.ncbi.nlm.nih.gov/12920188
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