Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Daniel R. Potter"'
Autor:
Shibani Pati, Zhanglong Peng, Katherine Wataha, Byron Miyazawa, Daniel R Potter, Rosemary A Kozar
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192363 (2018)
In severe trauma and hemorrhage the early and empiric use of fresh frozen plasma (FFP) is associated with decreased morbidity and mortality. However, utilization of FFP comes with the significant burden of shipping and storage of frozen blood product
Externí odkaz:
https://doaj.org/article/ddd8b326733e4c18893e2ecfe648913e
Autor:
Maximillian Lin, Alison B Nair, Daniel R. Potter, Martin A. Schreiber, Belinda H. McCully, Lindsay R. Vivona, Shibani Pati, Alpa Trivedi, Byron Miyazawa
Publikováno v:
Journal of Trauma and Acute Care Surgery. 89:1068-1075
BACKGROUND Hemorrhagic shock (HS) and trauma can result in an endotheliopathy of trauma, characterized by endothelial compromise, inflammation, and aberrant coagulation. Kcentra, a prothrombin concentrate, has been demonstrated to mitigate pulmonary
Autor:
Kristen Valanoski, Alpa Trivedi, Sawyer Smith, Stuart L. Gibb, Lindsay R. Vivona, Daniel R. Potter, James Murphy, Martin A. Schreiber, Shibani Pati, Philip J. Norris, Maximillian Lin, Byron Miyazawa, Mars Stone
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Journal of Translational Medicine
Journal of translational medicine, vol 17, iss 1
Journal of Translational Medicine
Journal of translational medicine, vol 17, iss 1
Background Cell based therapies, such as bone marrow derived mesenchymal stem cells (BM-MSCs; also known as mesenchymal stromal cells), are currently under investigation for a number of disease applications. The current challenge facing the field is
Autor:
Martin A. Schreiber, Shibani Pati, Matthew Dickerson, Manisha A. Khakoo, Daniel R. Potter, Maximillian Lin, Lindsay R. Vivona, Alpa Trivedi, Ben Antebi, Glen Michael Fitzpatrick, Rosemary A. Kozar, Amber Lee, Byron Miyazawa, John B. Holcomb, Braden Ishler
Publikováno v:
The journal of trauma and acute care surgery. 90(2)
Background Hemorrhagic shock (HS) and trauma induce endothelial barrier compromise, inflammation, and aberrant clotting. We have shown that fresh human platelets (Plts) and Plt extracellular vesicles mitigate vascular leak in murine models of injury.
Autor:
Amanda M. Chipman, Shibani Pati, Feng Wu, Daniel R. Potter, Rosemary A. Kozar, Maximillian Lin
Publikováno v:
J Trauma Acute Care Surg
BACKGROUND Clinical benefits of plasma as an adjunct for treatment of hemorrhagic shock (HS) have been well established. However, its use is not without risk. Little is understood regarding the clinical implications of plasma variability. We hypothes
Autor:
Xutao Deng, Michael A. Matthay, Alpa Trivedi, Martin A. Schreiber, Daniel R. Potter, Padma P. Togaratti, Amit K. Srivastava, Byron Miyazawa, Stuart L. Gibb, John B. Holcomb, Roxanne H. Croze, Shibani Pati
Publikováno v:
Journal of Trauma and Acute Care Surgery. 84:245-256
Background Mesenchymal stem cells (MSCs) have been shown to mitigate vascular permeability in hemorrhagic shock (HS) and trauma-induced brain and lung injury. Mechanistically, paracrine factors secreted from MSCs have been identified that can recapit
Autor:
Amit K. Srivastava, Lindsay R. Vivona, Alpa Trivedi, Martin A. Schreiber, Maximillian Lin, Alexander T. Fields, Byron Miyazawa, Gyulnar Baimukanova, Charles E. Wade, Lucy Z. Kornblith, Daniel R. Potter, Shibani Pati, Padma Priya Togarrati, Rachael A. Callcut, Ernesto Lopez, John B. Holcomb
Publikováno v:
J Trauma Acute Care Surg
The journal of trauma and acute care surgery, vol Publish Ahead of Print, iss &NA
The journal of trauma and acute care surgery, vol Publish Ahead of Print, iss &NA
BACKGROUND:Platelet (Plt) derived-extracellular vesicles (Plt-EVs) have hemostatic properties similar to Plts. In addition to hemostasis, Plts also function to stabilize the vasculature and maintain endothelial cell (EC) barrier integrity. We hypothe
Autor:
Gyulnar Baimukanova, Anthony N. Moore, Daniel R. Potter, Pramod K. Dash, Hasen Xue, Jing Zhao, Tyler D Menge, Stuart L. Gibb, John B. Holcomb, Yuhai Zhao, Shibani Pati, Charles S. Cox, Michael J. Hylin, Evan M. Johnson
Publikováno v:
Stem Cells. 34:1263-1272
Intravenous administration of bone marrow derived mesenchymal stem cells (MSCs) has been shown to reduce blood brain barrier compromise and improve neurocognition following traumatic brain injury (TBI). These effects occur in the absence of engraftme
Autor:
John B. Holcomb, David H. Farrel, Martin A. Schreiber, Daniel R. Potter, Shibani Pati, Gyulnar Baimukanova
Publikováno v:
Journal of Trauma and Acute Care Surgery. 80:576-585
Transfusion of balanced ratios of plasma to platelets and red blood cells has been shown to reduce early death from exsanguination in trauma patients. Aside from hemostasis, recent work has shown that plasma reduces vascular endothelial permeability,
Autor:
Roberta Bruhn, Mitchell J. Cohen, Stuart L. Gibb, Daniel R. Potter, Andrew P. Cap, Gyulnar Baimukanova, Byron Miyazawa, Marcus O. Muench, Philip C. Spinella, Shibani Pati
Publikováno v:
Transfusion. 56:S65-S75
BACKGROUND In current blood banking practices, platelets (PLTs) are stored in plasma at 22°C, with gentle agitation for up to 5 days. To date, the effects of storage and donor variability on PLT regulation of vascular integrity are not known. STUDY