Time-Domain Fluorescence Lifetime Imaging Techniques Suitable for Solid-State Imaging Sensor Arrays

Autor: Robert K. Henderson, Jochen Arlt, David Tyndall, Justin Richardson, Daniel R. Matthews, Viput Visitkul, Richard Walker, David Day-Uei Li, Simon Ameer-Beg

Publikováno v: Sensors, Vol 12, Iss 5, Pp 5650-5669 (2012)

We have successfully demonstrated video-rate CMOS single-photon avalanche diode (SPAD)-based cameras for fluorescence lifetime imaging microscopy (FLIM) by applying innovative FLIM algorithms. We also review and compare several time-domain techniques

Externí odkaz: https://doaj.org/article/3df36232feac4a1daceba9c8607ac5e3

TNFR1 membrane reorganization promotes distinct modes of TNFα signaling

Autor: Maddy Parsons, Camille Perrin, Daniel R. Matthews, David McMillan, Simon Ameer-Beg, Penny E. Morton, Richard J. Marsh, Simon P. Poland, Alison Maloney, James A. Levitt, Rosemary Pike

Publikováno v: Morton, P E, Perrin, C, Levitt, J, Matthews, D R, Marsh, R J, Pike, R, McMillan, D, Maloney, A, Poland, S, Ameer-Beg, S & Parsons, M 2019, ' TNFR1 membrane reorganization promotes distinct modes of TNFα signaling ', Science Signaling, vol. 12, no. 592, eaaw2418 . https://doi.org/10.1126/scisignal.aaw2418

Signaling by the ubiquitously expressed tumor necrosis factor receptor 1 (TNFR1) after ligand binding plays an essential role in determining whether cells exhibit survival or death. TNFR1 forms distinct signaling complexes that initiate gene expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5162811e6ba931e1da69b9765f0b37d
https://kclpure.kcl.ac.uk/en/publications/b0847b99-aa75-4614-8af7-a8e98b2de88a

Does interhemispheric communication relate to the bilateral function of muscles? A study of scapulothoracic muscles using transcranial magnetic stimulation

Autor: A. Risso, Daniel R. Matthews, P. Murtagh, G. Jones, Caroline M. Alexander

Publikováno v: Journal of Electromyography and Kinesiology. 23:1370-1374

Interhemispheric connections have been demonstrated between the motor cortex controlling muscle pairs. However, these investigations have tended to concentrate upon hand muscles. We have extended these investigations to proximal muscles that control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349546f1fc2b03747c5018fc3085f68c
https://doi.org/10.1016/j.jelekin.2013.06.007

Technique for measurement of fluorescence lifetime by use of stroboscopic excitation and continuous-wave detection

Autor: Borivoj Vojnovic, Simon Ameer-Beg, Paul R. Barber, Rachel J. Errington, Kerenza Njoh, Daniel R. Matthews, Paul J. Smith, Huw D. Summers

A study of the practicality a simple technique for obtaining time-domain information that uses continuous wave detection of fluorescence is presented. We show that this technique has potential for use in assays for which a change in the lifetime of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c3ed721b0a05ffd34f3ba880ec7c4d
https://ora.ox.ac.uk/objects/uuid:e19a0a1a-51b4-48df-9638-404bd77a75e2

Coronin 1B reorganizes the architecture of F-actin networks for contractility at steady-state and apoptotic adherens junctions

Autor: Siew Ping Han, Robert G. Parton, Bipul R. Acharya, Joyce C.M. Meiring, Michelle M. Hill, Magdalene Michael, Guillermo A. Gomez, Alpha S. Yap, Suzie Verma, Daniel R. Matthews

In this study we sought to identify how contractility at adherens junctions influences apoptotic cell extrusion. We first found that the generation of effective contractility at steady-state junctions entails a process of architectural reorganization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa0efaa36c662d34d3cdd1f4772a77b
https://hdl.handle.net/11541.2/125834