Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Daniel R. Lu"'
Autor:
Yi Huo, Zhen Sheng, Daniel R. Lu, Daniel C. Ellwanger, Chi-Ming Li, Oliver Homann, Songli Wang, Hong Yin, Ruibao Ren
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Bi-specific T-cell engager (BiTE) antibody is a class of bispecific antibodies designed for cancer immunotherapy. Blinatumomab is the first approved BiTE to treat acute B cell lymphoblastic leukemia (B-ALL). It brings killer T and
Externí odkaz:
https://doaj.org/article/88b9f96ffc8c48f29c00d36e749723dc
Autor:
Tracy M. Yamawaki, Daniel R. Lu, Daniel C. Ellwanger, Dev Bhatt, Paolo Manzanillo, Vanessa Arias, Hong Zhou, Oh Kyu Yoon, Oliver Homann, Songli Wang, Chi-Ming Li
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Elucidation of immune populations with single-cell RNA-seq has greatly benefited the field of immunology by deepening the characterization of immune heterogeneity and leading to the discovery of new subtypes. However, single-cell
Externí odkaz:
https://doaj.org/article/e6c3edf6b23b4041b41e0ead257ffb4d
Autor:
Michael A. Gonzalez, Daniel R. Lu, Maryam Yousefi, Ashley Kroll, Chen Hao Lo, Carlos G. Briseño, J. E. Vivienne Watson, Sergey Novitskiy, Vanessa Arias, Hong Zhou, Andres Plata Stapper, Min K. Tsai, Emily L. Ashkin, Christopher W. Murray, Chi-Ming Li, Monte M. Winslow, Kristin V. Tarbell
Publikováno v:
Journal of Experimental Medicine. 220
Phagocytosis is a key macrophage function, but how phagocytosis shapes tumor-associated macrophage (TAM) phenotypes and heterogeneity in solid tumors remains unclear. Here, we utilized both syngeneic and novel autochthonous lung tumor models in which
Autor:
Songli Wang, Zhen Sheng, Ruibao Ren, Daniel R. Lu, Chi-Ming Li, Yi Huo, Hong Yin, Oliver Homann, Daniel C. Ellwanger
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
BMC Genomics
BMC Genomics
Introduction Blinatumomab, a bi-specific T cell engager (BiTE®) combining the VH and VL domains of two antibodies against human CD19 and CD3, has been approved by U.S. Food and Drug Administration (FDA) for the treatment of patients with relapsed or
Autor:
Benjamin M. Basile, Vincent D. Costa, Jamie L. Schafroth, Chloe L. Karaskiewicz, Daniel R. Lucas, Elisabeth A. Murray
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Dual-process accounts of item recognition posit two memory processes: slow but detailed recollection, and quick but vague familiarity. It has been proposed, based on prior rodent work, that the amygdala is critical for the familiarity aspect
Externí odkaz:
https://doaj.org/article/7b2787fbe8d94c00864e943842e5fd1e
Autor:
Chi-Ming Kevin Li, Tracy M Yamawaki, Daniel R Lu, Daniel C Ellwanger, Dev Bhatt, Paolo Manzanillo, Hong Zhou, Oh-Kyu Yoon, Oliver Homann, Songli Wang
Background: Elucidation of immune populations with single-cell RNA-seq has greatly benefited the fieldof immunology by deepening the characterization of immune heterogeneity and leading to thediscovery of new subtypes. However, single-cell methods in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fff47b91485fb3814c7e5c559a579f
https://doi.org/10.21203/rs.3.rs-72851/v1
https://doi.org/10.21203/rs.3.rs-72851/v1
Autor:
Oliver Homann, Hong Zhou, Dev Bhatt, Tracy M. Yamawaki, Paolo Manzanillo, Daniel R. Lu, Chi-Ming Li, Oh Kyu Yoon, Songli Wang, Daniel C. Ellwanger
BackgroundElucidation of immune populations with single-cell RNA-seq has greatly benefited the field of immunology by deepening the characterization of immune heterogeneity and leading to the discovery of new subtypes. However, single-cell methods in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ebab59975a32f68d12a38d2fe01f25a
https://doi.org/10.1101/2020.09.04.283499
https://doi.org/10.1101/2020.09.04.283499
Autor:
Sarah Kongpachith, Andrew McDavid, Jacob Glanville, William H. Robinson, Chia-Hsin Ju, Raphael Gottardo, Nithya Lingampalli, Daniel R. Lu
Publikováno v:
Arthritis & Rheumatology. 70:1732-1744
Objective Rheumatoid arthritis (RA) is characterized by the activation of B cells that produce anti-citrullinated protein antibodies (ACPAs) and rheumatoid factors (RFs), but the mechanisms by which tolerance is broken in these B cells remain incompl
Autor:
Gentry Russell, MD, Pooja Navale, MD, Daniel R. Ludwig, MD, Benjamin S. Strnad, MD, Malak Itani, MD
Publikováno v:
Radiology Case Reports, Vol 18, Iss 10, Pp 3371-3375 (2023)
There are a wide range of benign and malignant pathologies that the radiologist may encounter in the adrenal glands and kidneys, often incidentally when imaging is performed for other indications. Many imaging modalities including CT, MR, and US are
Externí odkaz:
https://doaj.org/article/2b6b8755348d4100b306f53edfd95061
Autor:
Ian Driver, Daniel R. Lu, Songli Wang, Chi-Ming Li, Sue Sohn, Sarah Ingersoll, Hao Wu, Hyewon Phee
Publikováno v:
Life Science Alliance
Single-cell RNA-seq analysis reveals that IL-2 mutein treatment expands multiple sub-states of regulatory T cells with superior suppressive function in mice.
The therapeutic expansion of Foxp3+ regulatory T cells (Tregs) shows promise for treati
The therapeutic expansion of Foxp3+ regulatory T cells (Tregs) shows promise for treati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbeeada6cb21758e645c77f742f481c4
https://doi.org/10.1101/669978
https://doi.org/10.1101/669978