Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Daniel R. Leonce"'
Autor:
Lars Velten, Benjamin A. Story, Pablo Hernández-Malmierca, Simon Raffel, Daniel R. Leonce, Jennifer Milbank, Malte Paulsen, Aykut Demir, Chelsea Szu-Tu, Robert Frömel, Christoph Lutz, Daniel Nowak, Johann-Christoph Jann, Caroline Pabst, Tobias Boch, Wolf-Karsten Hofmann, Carsten Müller-Tidow, Andreas Trumpp, Simon Haas, Lars M. Steinmetz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Leukaemic stem cells drive acute myeloid leukaemia (AML) progression and relapse but they are incompletely characterized. Here, the authors combine single-cell transcriptomics and clonal tracking using nuclear and mitochondrial somatic variants to di
Externí odkaz:
https://doaj.org/article/7f3244539bc54da0bc5ec3fba0f6edbe
Autor:
Simon Haas, Magdalena Antes, Daniel R. Leonce, Daniel Hübschmann, Tobias Boch, Sergio Triana, Diana Ordoñez-Rueda, Dominik Vonficht, Malte Paulsen, Lea Jopp-Saile, Daniel Nowak, Lars Velten, Theodore Alexandrov, Wolf-Karsten Hofmann, Johann-Christoph Jann, Andreas Trumpp, Pablo Hernández-Malmierca, Carsten Müller-Tidow, Raphael Lutz, Simon Raffel, Vladimir Benes, Beáta Ramasz
Single-cell genomics has transformed our understanding of complex cellular systems. However, excessive costs and a lack of strategies for the purification of newly identified cell types impede their functional characterization and large-scale profili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd3fbed1af87b209ce80ed8ce5ed8bc
https://doi.org/10.1101/2021.03.18.435922
https://doi.org/10.1101/2021.03.18.435922
Autor:
Christoph Lutz, Simon Haas, Pablo Hernández-Malmierca, Lars Velten, Caroline Pabst, Daniel Nowak, Tobias Boch, Chelsea Szu-Tu, Benjamin A. Story, Aykut Demir, Robert Frömel, Wolf-Karsten Hofmann, Jennifer Milbank, Malte Paulsen, Daniel R. Leonce, Carsten Müller-Tidow, Simon Raffel, Andreas Trumpp, Lars M. Steinmetz, Johann-Christoph Jann
Publikováno v:
Nature Communications, 12 (1)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Cancer stem cells drive disease progression and relapse in many types of cancer. Despite this, a thorough characterization of these cells remains elusive and with it the ability to eradicate cancer at its source. In acute myeloid leukemia (AML), leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ec4fb26a46903d0f84cbb2b6145fba
https://hdl.handle.net/20.500.11850/474268
https://hdl.handle.net/20.500.11850/474268
Autor:
Simon Haas, Daniel Nowak, Lea Jopp-Saile, Daniel Hübschmann, Beáta Ramasz, Theodore Alexandrov, Carsten Müller-Tidow, Sergio Triana, Magdalena Antes, Tobias Boch, Dominik Vonficht, Simon Raffel, Lars Velten, Johann-Christoph Jann, Diana Ordoñez-Rueda, Raphael Lutz, Vladimir Benes, Malte Paulsen, Daniel R. Leonce, Pablo Hernández-Malmierca, Wolf-Karsten Hofmann, Andreas Trumpp
Publikováno v:
Nature Immunology
Triana, S, Vonficht, D, Jopp-Saile, L, Raffel, S, Lutz, R, Leonce, D, Antes, M, Hernández-Malmierca, P, Ordoñez-Rueda, D, Ramasz, B, Boch, T, Jann, J C, Nowak, D, Hofmann, W K, Müller-Tidow, C, Hübschmann, D, Alexandrov, T, Benes, V, Trumpp, A, Paulsen, M, Velten, L & Haas, S 2021, ' Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states ', Nature Immunology, vol. 22, no. 12, pp. 1577-1615 . https://doi.org/10.1038/s41590-021-01059-0
Triana, S, Vonficht, D, Jopp-Saile, L, Raffel, S, Lutz, R, Leonce, D, Antes, M, Hernández-Malmierca, P, Ordoñez-Rueda, D, Ramasz, B, Boch, T, Jann, J C, Nowak, D, Hofmann, W K, Müller-Tidow, C, Hübschmann, D, Alexandrov, T, Benes, V, Trumpp, A, Paulsen, M, Velten, L & Haas, S 2021, ' Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states ', Nature Immunology, vol. 22, no. 12, pp. 1577-1615 . https://doi.org/10.1038/s41590-021-01059-0
Single-cell genomics technology has transformed our understanding of complex cellular systems. However, excessive cost and a lack of strategies for the purification of newly identified cell types impede their functional characterization and large-sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ad3710d2ca8d5980e41bd162b3ebb9
Autor:
Petra Jakob, Daniel R. Leonce, Lukas Mathur, Jan O. Korbel, Lars Velten, Jennifer Milbank, Christoph A. Merten, Andreas R Gschwind, Daniel Schraivogel, Lars M. Steinmetz
Publikováno v:
Nature methods
Nature Methods
Nature Methods
The transcriptome contains rich information on molecular, cellular and organismal phenotypes. However, experimental and statistical limitations constrain sensitivity and throughput of genetic screening with single-cell transcriptomics readout. To ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec163bc8d99492101ed4335b209c9c8c
https://infoscience.epfl.ch/record/279742
https://infoscience.epfl.ch/record/279742