Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Daniel R. Garalde"'
Autor:
Miranda P.G. Zalusky, Jonas A. Gustafson, Stephanie C. Bohaczuk, Ben Mallory, Paxton Reed, Tara Wenger, Erika Beckman, Irene J. Chang, Cate R. Paschal, Jillian G. Buchan, Christina M. Lockwood, Mihai Puia-Dumitrescu, Daniel R. Garalde, Joseph Guillory, Androo J. Markham, Michael J. Bamshad, Evan E. Eichler, Andrew B. Stergachis, Danny E. Miller
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101833- (2024)
Purpose: Rapid genetic testing in the critical care setting may guide diagnostic evaluation, direct therapies, and help families and care providers make informed decisions about goals of care. We tested whether a simplified DNA extraction and library
Externí odkaz:
https://doaj.org/article/6d44b504cf61496087437a8f47863416
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216709 (2019)
The ribosome small subunit is expressed in all living cells. It performs numerous essential functions during translation, including formation of the initiation complex and proofreading of base-pairs between mRNA codons and tRNA anticodons. The core c
Externí odkaz:
https://doaj.org/article/9e5c8a1867784e43bb43a743fc1b13d6
Autor:
Sneha D. Goenka, John E. Gorzynski, Kishwar Shafin, Dianna G. Fisk, Trevor Pesout, Tanner D. Jensen, Jean Monlong, Pi-Chuan Chang, Gunjan Baid, Jonathan A. Bernstein, Jeffrey W. Christle, Karen P. Dalton, Daniel R. Garalde, Megan E. Grove, Joseph Guillory, Alexey Kolesnikov, Maria Nattestad, Maura R. Z. Ruzhnikov, Mehrzad Samadi, Ankit Sethia, Elizabeth Spiteri, Christopher J. Wright, Katherine Xiong, Tong Zhu, Miten Jain, Fritz J. Sedlazeck, Andrew Carroll, Benedict Paten, Euan A. Ashley
Publikováno v:
Nature Biotechnology. 40:1035-1041
Whole-genome sequencing (WGS) can identify variants that cause genetic disease, but the time required for sequencing and analysis has been a barrier to its use in acutely ill patients. In the present study, we develop an approach for ultra-rapid nano
Autor:
Miranda Galey, Paxton Reed, Tara Wenger, Erika Beckman, Irene J. Chang, Cate R. Paschal, Jillian G. Buchan, Christina M. Lockwood, Mihai Puia-Dumitrescu, Daniel R. Garalde, Joseph Guillory, Androo J. Markham, Andrew B. Stergachis, Michael J. Bamshad, Evan E. Eichler, Danny E. Miller
Rapid genetic testing in the critical care setting enables targeted evaluations, directs therapies, and helps families and care providers make informed decisions about goals of care. We tested whether we could perform ultra-rapid assessment of geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb85a1267b4ff7ec6729cb39f946a6d9
https://doi.org/10.1101/2022.09.09.22279746
https://doi.org/10.1101/2022.09.09.22279746
Autor:
John E. Gorzynski, Sneha D. Goenka, Kishwar Shafin, Tanner D. Jensen, Dianna G. Fisk, Megan E. Grove, Elizabeth Spiteri, Trevor Pesout, Jean Monlong, Gunjan Baid, Jonathan A. Bernstein, Scott Ceresnak, Pi-Chuan Chang, Jeffrey W. Christle, Henry Chubb, Karen P. Dalton, Kyla Dunn, Daniel R. Garalde, Joseph Guillory, Joshua W. Knowles, Alexey Kolesnikov, Michael Ma, Tia Moscarello, Maria Nattestad, Marco Perez, Maura R.Z. Ruzhnikov, Mehrzad Samadi, Ankit Setia, Chris Wright, Courtney J. Wusthoff, Katherine Xiong, Tong Zhu, Miten Jain, Fritz J. Sedlazeck, Andrew Carroll, Benedict Paten, Euan A. Ashley
Publikováno v:
New England Journal of Medicine. 386:700-702
Autor:
John E. Gorzynski, Sneha D. Goenka, Kishwar Shafin, Tanner D. Jensen, Dianna G. Fisk, Megan E. Grove, Elizabeth Spiteri, Trevor Pesout, Jean Monlong, Jonathan A. Bernstein, Scott Ceresnak, Pi-Chuan Chang, Jeffrey W. Christle, Henry Chubb, Kyla Dunn, Daniel R. Garalde, Joseph Guillory, Maura R.Z. Ruzhnikov, Chris Wright, Courtney J. Wusthoff, Katherine Xiong, Seth A. Hollander, Gerald J. Berry, Miten Jain, Fritz J. Sedlazeck, Andrew Carroll, Benedict Paten, Euan A. Ashley
Publikováno v:
Circulation. Genomic and precision medicine. 15(2)
Reading canonical and modified nucleobases in 16S ribosomal RNA using nanopore native RNA sequencing
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216709 (2019)
PLoS ONE
PLoS ONE
The ribosome small subunit is expressed in all living cells. It performs numerous essential functions during translation, including formation of the initiation complex and proofreading of base-pairs between mRNA codons and tRNA anticodons. The core c
Reading canonical and modified nucleotides in 16S ribosomal RNA using nanopore direct RNA sequencing
The ribosome small subunit is expressed in all living cells. It performs numerous essential functions during translation, including formation of the initiation complex and proofreading of base-pairs between mRNA codons and tRNA anticodons. The core c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b25b7517e136e783d395dc19fad645
https://doi.org/10.1101/132274
https://doi.org/10.1101/132274
Autor:
Donald M. Wiberg, Daniel R. Garalde, Gang Wang, William B. Dunbar, Raj D. Maitra, Christopher R. O'Donnell
Publikováno v:
IEEE Transactions on Control Systems Technology. 21:2038-2051
The nanopore is a powerful tool for probing biomolecular interactions at the single-molecule level, and shows great promise commercially as a next-generation deoxyribonucleic acid (DNA) sequencing technology. Coupling active voltage control with the
Autor:
Andre Marziali, Ai H. Mai, Hongyun Wang, Mark Akeson, Nahid N. Jetha, Joseph M. Dahl, Gerald M. Cherf, Kate R. Lieberman, Daniel R. Garalde
Publikováno v:
Journal of Biological Chemistry. 287:13407-13421
Complexes of phi29 DNA polymerase and DNA fluctuate on the millisecond time scale between two ionic current amplitude states when captured atop the α-hemolysin nanopore in an applied field. The lower amplitude state is stabilized by complementary dN