Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Daniel R. Frederick"'
Autor:
Kimberly A. Walker, Taryn A. Miner, Michelle Palacios, Dominika Trzilova, Daniel R. Frederick, Christopher A. Broberg, Victoria E. Sepúlveda, Joshua D. Quinn, Virginia L. Miller
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The polysaccharide capsule is an essential virulence factor for Klebsiella pneumoniae in both community-acquired hypervirulent strains as well as health care-associated classical strains that are posing significant challenges due to multidru
Externí odkaz:
https://doaj.org/article/d253aa4c055244b39986388f75d67fdc
Autor:
Justin A. Spanier, Daniel R. Frederick, Justin J. Taylor, James R. Heffernan, Dmitri I. Kotov, Tijana Martinov, Kevin C. Osum, Jenna L. Ruggiero, Blake J. Rust, Samuel J. Landry, Marc K. Jenkins, James B. McLachlan, Brian T. Fife
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Generating antibodies specific for the peptide–MHCII complexes has been challenging, with only a handful made to date. Here, the authors develop a more efficient approach to generate these antibodies, and demonstrate their potential in research and
Externí odkaz:
https://doaj.org/article/8c2e27eaab1b4cc89a8d7d85fe9db231
Autor:
Michelle Palacios, Taryn A. Miner, Daniel R. Frederick, Victoria E. Sepulveda, Joshua D. Quinn, Kimberly A. Walker, Virginia L. Miller
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Klebsiella pneumoniae is widely recognized as a pathogen with a propensity for acquiring antibiotic resistance. It is capable of causing a range of hospital-acquired infections (urinary tract infections [UTI], pneumonia, sepsis) and communit
Externí odkaz:
https://doaj.org/article/f39045d829a44c37afed7e39105cd7c3
Autor:
L M Sabbagh, John D. Clements, James B. McLachlan, Lucy C. Freytag, J A Goggins, Daniel R. Frederick
Publikováno v:
Mucosal Immunology. 11:549-561
Infectious diarrheal diseases are the second leading cause of death in children under 5 years, making vaccines against these diseases a high priority. It is known that certain vaccine adjuvants, chiefly bacterial ADP-ribosylating enterotoxins, can in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff47a2e7b1a62efa9f29ca8957902e4f
https://doi.org/10.1038/mi.2017.70
https://doi.org/10.1038/mi.2017.70
Autor:
Daniel R. Frederick, Victoria E. Sepúlveda, Kimberly A. Walker, Michelle Palacios, Dominika Trzilova, Virginia L. Miller, Taryn A. Miner, Christopher A. Broberg, Joshua D. Quinn
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e00089-19 (2019)
mBio
mBio, Vol 10, Iss 2, p e00089-19 (2019)
mBio
Klebsiella pneumoniae continues to be a substantial public health threat due to its ability to cause health care-associated and community-acquired infections combined with its ability to acquire antibiotic resistance. Novel therapeutics are needed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec21908567541af4926c34fed3c03910
https://doi.org/10.1128/mbio.00089-19
https://doi.org/10.1128/mbio.00089-19
Autor:
Kevin C. Osum, Justin J. Taylor, Blake J. Rust, Marc K. Jenkins, Jenna L. Ruggiero, Samuel J. Landry, Tijana Martinov, James Heffernan, Brian T. Fife, Justin A. Spanier, Dmitri I. Kotov, James B. McLachlan, Daniel R. Frederick
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Communications
Monoclonal antibodies specific for foreign antigens, auto-antigens, allogeneic antigens and tumour neo-antigens in the context of major histocompatibility complex II (MHCII) are highly desirable as novel immunotherapeutics. However, there is no stand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b511cd51952f7f2b226a48717c720d01
https://doaj.org/article/8c2e27eaab1b4cc89a8d7d85fe9db231
https://doaj.org/article/8c2e27eaab1b4cc89a8d7d85fe9db231
Autor:
Lisa A. Morici, Jonathan R Kurtz, Daniel R. Frederick, Hailey E. Petersen, James B. McLachlan
Publikováno v:
Infection and Immunity. 82:2424-2433
Salmonella infections affect millions worldwide and remain a significant cause of morbidity and mortality. It is known from mouse studies that CD4 T cells are essential mediators of immunity against Salmonella infection, yet it is not clear whether t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6ccfee31feea40c93744e0c41596ca
https://doi.org/10.1128/iai.00052-14
https://doi.org/10.1128/iai.00052-14
Publikováno v:
Palaeogeography, Palaeoclimatology, Palaeoecology. 127:191-207
The appearance of faunal stability in the fossil record occurs because mainly abundant species are preserved and sampled. The paleontologist does not therefore observe many rare species with high ecological and evolutionary turnover rates. High ecolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20e606962a10c858e68bccc8f6cdbf79
https://doi.org/10.1016/s0031-0182(96)00095-8
https://doi.org/10.1016/s0031-0182(96)00095-8
Autor:
John F. Alcorn, Bruce R. Pitt, Linda L. Pearce, Jim Peterson, A. Murat Kaynar, Iris Kaminski, Derek C. Angus, Lin Zhu, Cheryl L. Fattman, Joseph N. McLaughlin, Joseph D. Latoche, Daniel R. Frederick, Sang-Min Lee, Kalidasan Thambiayya, Tim D. Oury, Jin Li, Karla J. Wasserloos, Octavia M. Peck Palmer, Donna B. Stolz
Hypozincemia, with hepatic zinc accumulation at the expense of other organs, occurs in infection, inflammation, and aseptic lung injury. Mechanisms underlying zinc partitioning or its impact on extrahepatic organs are unclear. Here we show that the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dee0b1ce1a798197e38d8e13c75df99
https://europepmc.org/articles/PMC3602737/
https://europepmc.org/articles/PMC3602737/
Autor:
Joseph N. McLaughlin, Sachin Yende, Robert E. Ferrell, Derek C. Angus, Lin Zhu, J Rella, Daniel R. Frederick, Ahmet Bakan, Lan Kong, Steven D. Shapiro, Ivet Bahar, Ata Murat Kaynar
Publikováno v:
Critical Care
Animal studies suggest matrix metalloproteinase-8 (MMP8) (neutrophil collagenase) impairs neutrophil (PMN) recruitment in inflammation; in humans, MMP8 has been associated with inflammation. We hypothesized that septic patients with single nucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb05cdffa3faa4f517820cc57f79ff2
https://doi.org/10.1186/cc9698
https://doi.org/10.1186/cc9698