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of 319
pro vyhledávání: '"Daniel R. Doerge"'
Publikováno v:
Environment International, Vol 144, Iss , Pp 106086- (2020)
Arsenic (As) is a common contaminant in the earth’s crust and widely distributed in food and drinking water. As exposures have been associated with human disease, including cancer, diabetes, lung and cardiovascular disorders, and there is accumulat
Externí odkaz:
https://doaj.org/article/4785caec25c94b31bfd8917f25a78a3c
Autor:
Kuppan Gokulan, Matthew G. Arnold, Jake Jensen, Michelle Vanlandingham, Nathan C. Twaddle, Daniel R. Doerge, Carl E. Cerniglia, Sangeeta Khare
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Intestinal microbiota composition and gut-associated immune response can contribute to the toxicity of arsenic. We investigated the potential toxicity of short-term arsenic exposure on gut microbiome composition, intestinal immune status, mi
Externí odkaz:
https://doaj.org/article/a705a27fc34149fab82d483c7b6fb653
Autor:
Justin G. Teeguarden, Nathan C. Twaddle, Mona I. Churchwell, Xiaoxia Yang, Jeffrey W. Fisher, Liesel M. Seryak, Daniel R. Doerge
Publikováno v:
Data in Brief, Vol 4, Iss C, Pp 83-86 (2015)
Here we present data to evaluate potential absorption of Bisphenol A through non-metabolizing tissues of the upper digestive tract. Concurrent serum and urine concentrations of d6-BPA, and its glucuronide and sulfate conjugates, were measured over a
Externí odkaz:
https://doaj.org/article/ead971fdcfe641ac9ee1573b194405d8
Autor:
Yiwei Li, Mingxin Che, Sunita Bhagat, Kerrie-Lynn Ellis, Omer Kucuk, Daniel R. Doerge, Judith Abrams, Michael L. Cher, Fazlul H. Sarkar
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 4, Pp 354-363 (2004)
Prostate cancer frequently metastasizes to the bone, and the treatment outcome for metastatic prostate cancer has been disappointing so far. Dietary genistein, derived primarily from soy product, has been proposed to be partly responsible for the low
Externí odkaz:
https://doaj.org/article/a0a538acdd684ad2ae2c198978d2e195
Publikováno v:
Food and Chemical Toxicology. 130:22-31
Arsenic species contaminate food and water, with typical dietary intake below 1 μg/kg bw/d. Exposure to arsenic in heavily contaminated drinking water is associated with human diseases, including cardiovascular and respiratory disorders, diabetes, a
Autor:
Daniel R. Doerge, Mona I. Churchwell, Paritosh Pande, Nathan C. Twaddle, Justin G. Teeguarden, Stefanie C. Fleck
Publikováno v:
Food and Chemical Toxicology. 125:341-353
Evaluating the biological significance of human-relevant exposures to environmental estrogens involves assessing the individual and total estrogenicity of endogenous and exogenous estrogens found in serum, for example from biomonitoring studies. We d
Autor:
Daniel R. Doerge, Frederick A. Beland, Nathan C. Twaddle, Jeffrey W. Fisher, Michelle Vanlandingham
Publikováno v:
Food and Chemical Toxicology. 123:28-41
Arsenic is a ubiquitous contaminant, with typical human dietary intake below 1 μg/kg bw/d and extreme drinking water exposures up to ∼50 μg/kg bw/d. The formation and binding of trivalent metabolites are central to arsenic toxicity and strong hum
Autor:
Atsushi Ono, Yasushi Yamazoe, George E.N. Kass, Takashi Yamada, Daniel R. Doerge, Kaoruko Tachibana, Weida Tong
Publikováno v:
Food Safety
This is a summary report of FSCJ (Food Safety Commission of Japan) workshop entitled “Future Challenges and Opportunities in Developing Methodologies for Improved Human Risk Assessments, which held in November 2018. Scientific advancements have fac
Autor:
Kaitlyn M. Joyce, Carmen P. Wong, Ian A. Scriven, Dawn A. Olson, Daniel R. Doerge, Adam J. Branscum, Lara H. Sattgast, William G. Helferich, Russell T. Turner, Urszula T. Iwaniec
Publikováno v:
Molecular Nutrition & Food Research. 66:2100974
A dose-ranging study is performed using young estrogen-depleted rats to determine whether dietary isoliquiritigenin (ILQ) alters bone metabolism and if the effects are associated with estrogen receptor signaling.Six-week-old rats (ovariectomized at 4
Publikováno v:
Environment International, Vol 144, Iss, Pp 106086-(2020)
Arsenic (As) is a common contaminant in the earth's crust and widely distributed in food and drinking water. As exposures have been associated with human disease, including cancer, diabetes, lung and cardiovascular disorders, and there is accumulatin