Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Daniel R. Caffrey"'
Autor:
Juliet N. Crabtree, Daniel R. Caffrey, Leandro de Souza Silva, Evelyn A. Kurt-Jones, Katherine Dobbs, Arlene Dent, Katherine A. Fitzgerald, Douglas T. Golenbock
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Plasmodium falciparum (P. falciparum) induces trained innate immune responses in vitro, where initial stimulation of adherent PBMCs with P. falciparum–infected RBCs (iRBCs) results in hyperresponsiveness to subsequent ligation of TLR2. This respons
Externí odkaz:
https://doaj.org/article/87fa16923ed24d2c9c9df479b4432fac
Autor:
Monika Gulia-Nuss, Andrew B. Nuss, Jason M. Meyer, Daniel E. Sonenshine, R. Michael Roe, Robert M. Waterhouse, David B. Sattelle, José de la Fuente, Jose M. Ribeiro, Karine Megy, Jyothi Thimmapuram, Jason R. Miller, Brian P. Walenz, Sergey Koren, Jessica B. Hostetler, Mathangi Thiagarajan, Vinita S. Joardar, Linda I. Hannick, Shelby Bidwell, Martin P. Hammond, Sarah Young, Qiandong Zeng, Jenica L. Abrudan, Francisca C. Almeida, Nieves Ayllón, Ketaki Bhide, Brooke W. Bissinger, Elena Bonzon-Kulichenko, Steven D. Buckingham, Daniel R. Caffrey, Melissa J. Caimano, Vincent Croset, Timothy Driscoll, Don Gilbert, Joseph J. Gillespie, Gloria I. Giraldo-Calderón, Jeffrey M. Grabowski, David Jiang, Sayed M. S. Khalil, Donghun Kim, Katherine M. Kocan, Juraj Koči, Richard J. Kuhn, Timothy J. Kurtti, Kristin Lees, Emma G. Lang, Ryan C. Kennedy, Hyeogsun Kwon, Rushika Perera, Yumin Qi, Justin D. Radolf, Joyce M. Sakamoto, Alejandro Sánchez-Gracia, Maiara S. Severo, Neal Silverman, Ladislav Šimo, Marta Tojo, Cristian Tornador, Janice P. Van Zee, Jesús Vázquez, Filipe G. Vieira, Margarita Villar, Adam R. Wespiser, Yunlong Yang, Jiwei Zhu, Peter Arensburger, Patricia V. Pietrantonio, Stephen C. Barker, Renfu Shao, Evgeny M. Zdobnov, Frank Hauser, Cornelis J. P. Grimmelikhuijzen, Yoonseong Park, Julio Rozas, Richard Benton, Joao H. F. Pedra, David R. Nelson, Maria F. Unger, Jose M. C. Tubio, Zhijian Tu, Hugh M. Robertson, Martin Shumway, Granger Sutton, Jennifer R. Wortman, Daniel Lawson, Stephen K. Wikel, Vishvanath M. Nene, Claire M. Fraser, Frank H. Collins, Bruce Birren, Karen E. Nelson, Elisabet Caler, Catherine A. Hill
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Ticks transmit a large number of pathogens that cause human diseases. Here, the authors sequence the genome of the tick Ixodes scapularisand uncover expansion of genes associated with parasitic processes unique to ticks and tick-host interactions.
Externí odkaz:
https://doaj.org/article/fa4043b3779c4d0db50b094e385f7e3b
Autor:
Leandro de Souza Silva, Yen Anh H. Nguyen, Brian G. Monks, Catherine S. Forconi, Juliet N. Crabtree, Tomás Rodriguez, Nelsy De Paula Tamburro, Erik J. Sontheimer, Gabor L. Horvath, Zeinab Abdullah, Eicke Latz, Daniel R. Caffrey, Evelyn A. Kurt-Jones, Ricardo T. Gazzinelli, Katherine A. Fitzgerald, Douglas T. Golenbock
Subclinical (asymptomatic) parasitemia is very common amongstPlasmodium-infected individuals. The immunological mechanisms underlying subclinical parasitemia remain elusive. We investigated the immune regulatory mechanisms behind chronic asymptomatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d77c9dbd9aee591660c4a9a8bf7de2c1
https://doi.org/10.1101/2023.02.23.529826
https://doi.org/10.1101/2023.02.23.529826
Autor:
Jason D. Hughes, Daniel R. Caffrey, Simone Sciabola, Dario Cruz, Tianhong Zhang, Qing Cao, Robert V. Stanton, Hualin Xi, Sergio Rotstein, Christine Lawrence
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0238753 (2021)
PLoS ONE
PLoS ONE
PFRED a software application for the design, analysis, and visualization of antisense oligonucleotides and siRNA is described. The software provides an intuitive user-interface for scientists to design a library of siRNA or antisense oligonucleotides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae3d6cc288481e3e327c9452193e92d
https://doaj.org/article/be263efdf1364ef8aaa493f2ff09ba77
https://doaj.org/article/be263efdf1364ef8aaa493f2ff09ba77
Autor:
Te-Chen Tzeng, Shigeo Okabe, Douglas T. Golenbock, Kensuke Futai, Michael T. Heneka, Wenjie Mao, Daniel R. Caffrey, Nelsy DePaula Tamburro, Elizabeth Jeanne Thatcher, Eicke Latz, Yuto Hasegawa, Risa Iguchi, Amy Cheung, Gail Germain
Publikováno v:
Proceedings of the National Academy of Sciences. 115:9002-9007
Alzheimer’s disease (AD) is characterized by the progressive destruction and dysfunction of central neurons. AD patients commonly have unprovoked seizures compared with age-matched controls. Amyloid peptide-related inflammation is thought to be an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090c5cb0d109582b1ca410b8b221c21f
https://doi.org/10.1073/pnas.1801802115
https://doi.org/10.1073/pnas.1801802115
SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans
Autor:
Amanda J. Monahan, Donggi Paik, Roland Elling, William E. Goldman, Daniel R. Caffrey, Neal S. Silverman
Publikováno v:
The Journal of Immunology. 199:263-270
Tracheal cytotoxin (TCT), a monomer of DAP-type peptidoglycan from Bordetella pertussis, causes cytopathology in the respiratory epithelia of mammals and robustly triggers the Drosophila Imd pathway. PGRP-LE, a cytosolic innate immune sensor in Droso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b762705fa19761b2fd0d3235595f2a3
https://doi.org/10.4049/jimmunol.1600409
https://doi.org/10.4049/jimmunol.1600409
Autor:
Katherine A. Fitzgerald, Maninjay K. Atianand, Susan Carpenter, Roland Elling, Zhaozhao Jiang, Jennie Chan, Daniel R. Caffrey, Daniel Aiello
Publikováno v:
The Journal of Immunology. 195:1359-1363
Natural antisense transcripts (NATs) are a class of long noncoding RNAs (lncRNAs) that are complementary to other protein-coding genes. Although thousands of NATs are encoded by mammalian genomes, their functions in innate immunity are unknown. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87de5ad2555949a07ae1069866cd928b
https://doi.org/10.4049/jimmunol.1500264
https://doi.org/10.4049/jimmunol.1500264
Autor:
Jeffrey D. Jensen, Matthieu Foll, Ping Liu, Daniel N. Bolon, Celia A. Schiffer, Jennifer P. Wang, Sergey V. Venev, Daniel R. Caffrey, Serena T. Pham, Robert W. Finberg, Konstantin B. Zeldovich, Timothy F. Kowalik, Evelyn A. Kurt-Jones, Glen R. Gallagher, Nicholas Renzette
Publikováno v:
Molecular Biology and Evolution. 32:1519-1532
Influenza A virus (IAV) has a segmented genome that allows for the exchange of genome segments between different strains. This reassortment accelerates evolution by breaking linkage, helping IAV cross species barriers to potentially create highly vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c973d75cf09965e32ef7943ac9dd0f3a
https://doi.org/10.1093/molbev/msv044
https://doi.org/10.1093/molbev/msv044
Autor:
Katherine A. Fitzgerald, Omid F. Harandi, Parisa Kalantari, Evelyn A. Kurt-Jones, Florentina Rus, Douglas T. Golenbock, Sarika Agarwal, Daniel R. Caffrey
Bacterial sepsis involves a complex interaction between the host immune response and bacterial LPS. LPS binds Toll-like receptor (TLR) 4, which leads to the release of proinflammatory cytokines that are essential for a potent innate immune response a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9d3b2628eaaf7bd135c664b2b3b0cf
https://europepmc.org/articles/PMC5392559/
https://europepmc.org/articles/PMC5392559/
Publikováno v:
Annual Review of Immunology
The discovery of long noncoding RNAs (lncRNA) has provided a new perspective on gene regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that interact with RNA, DNA, or proteins to promote or restrain the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16105a2e682838d0c1f7ada69c42c88d
https://pubmed.ncbi.nlm.nih.gov/28125358
https://pubmed.ncbi.nlm.nih.gov/28125358