Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Daniel R Principe"'
Autor:
Stanley Borowicz, Daniel R Principe, Matthew J Dorman, Austin J McHenry, Gautam Sondarva, Sandeep Kumar, Vijayalakshmi Ananthanarayanan, Patricia E Simms, Ashley Hess, Ajay Rana
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252197 (2021)
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Though immune checkpoint inhibitors (ICIs) have revolutionized lung cancer therapy in recent years, there are several factors limiting the therapeutic efficacy
Externí odkaz:
https://doaj.org/article/25fe873de866459c8a595831290f2495
Autor:
Megha Singhal, Mahsa Khatibeghdami, Daniel R Principe, Georgina E Mancinelli, Kyle M Schachtschneider, Lawrence B Schook, Paul J Grippo, Sam R Grimaldo
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0211711 (2019)
Current therapies for pancreatic ductal adenocarcinoma (PDAC) only modestly impact survival and can be highly toxic. A greater understanding of the molecules regulating this disease is critical for identifying new drug targets and developing more eff
Externí odkaz:
https://doaj.org/article/55f1db67793741ae944612964f9e2a33
Autor:
Kanchan Vishnoi, Rong Ke, Navin Viswakarma, Piush Srivastava, Sandeep Kumar, Subhasis Das, Sunil Kumar Singh, Daniel R. Principe, Ajay Rana, Basabi Rana
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-16 (2022)
Abstract The incidence and mortality of hepatocellular carcinoma (HCC) are on a rise in the Western countries including US, attributed mostly to late detection. Sorafenib has been the first-line FDA-approved drug for advanced unresectable HCC for alm
Externí odkaz:
https://doaj.org/article/3ffdf7ee46924e22ae8d4086e6cc67db
Autor:
Daniel R. Principe
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy and are now the preferred treatment for several tumor types. Though ICIs have shown remarkable efficacy in several cancer histologies, in many cases providing long-term d
Externí odkaz:
https://doaj.org/article/7da5091a08404c72bb81aa7a244707a6
Autor:
Daniel R. Principe
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Abstract Colorectal cancer (CRC) is a leading cause of cancer‐related death worldwide. Although overall outcomes have improved in recent decades, metastatic disease is associated with a particularly poor prognosis, underscoring a need to both ident
Externí odkaz:
https://doaj.org/article/cbce58f3c0c0456f9e15756ab0fd9ac2
Autor:
Ajay Rana, Paul J. Grippo, Hidayatullah G. Munshi, Ronald McKinney, Carolina Torres, Jonathan Rubin, Navin Viswakarma, Sandeep Kumar, Matthew J. Dorman, Alex Park, Daniel R. Principe
Figure S1 shows that T-cell deficiency of TGFBR1 promotes an immune response against established pancreatic neoplasms. Interestingly, this was not recapitulated via systemic reduction of TGFBR1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06554333f77a4e2010b1adc8862823bb
https://doi.org/10.1158/1535-7163.22505817.v1
https://doi.org/10.1158/1535-7163.22505817.v1
Autor:
Ajay Rana, Paul J. Grippo, Hidayatullah G. Munshi, Ronald McKinney, Carolina Torres, Jonathan Rubin, Navin Viswakarma, Sandeep Kumar, Matthew J. Dorman, Alex Park, Daniel R. Principe
Pancreatic ductal adenocarcinoma (PDAC) remains remarkably lethal with a 5-year survival rate of 8%. This is mainly attributed to the late stage of presentation, as well as widespread resistance to conventional therapy. In addition, PDAC tumors are l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d677048e550cb2909525bd646316a731
https://doi.org/10.1158/1535-7163.c.6538185.v1
https://doi.org/10.1158/1535-7163.c.6538185.v1
Autor:
Paul J. Grippo, Barbara Jung, Hidayatullah G. Munshi, David J. Bentrem, Deyu Fang, David W. Dawson, Boris Pasche, Rosa Hwang, Naomi Akagi, Andrew M. Diaz, Elizabeth A. Wayne, Emman Mascariñas, Brian DeCant, Daniel R. Principe
Figure S6. Global TGFBR-Deficiency does not Alter Non-Peripheral Tregs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0048aca13df700f66e9f2843438082f5
https://doi.org/10.1158/0008-5472.22411965.v1
https://doi.org/10.1158/0008-5472.22411965.v1
Autor:
Paul J. Grippo, Barbara Jung, Hidayatullah G. Munshi, David J. Bentrem, Deyu Fang, David W. Dawson, Boris Pasche, Rosa Hwang, Naomi Akagi, Andrew M. Diaz, Elizabeth A. Wayne, Emman Mascariñas, Brian DeCant, Daniel R. Principe
Supplemental Methods and Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ce5751331e4c68365394074a45cbfc
https://doi.org/10.1158/0008-5472.22411953
https://doi.org/10.1158/0008-5472.22411953
Autor:
Ajay Rana, Jose G. Trevino, Hidayatullah G. Munshi, Patrick W. Underwood, Dinesh Thummuri, Rosa F. Hwang, Melissa L. Fishel, Paul J. Grippo, Suneel D. Kamath, Matthew J. Dorman, Navin Viswakarma, Alex Park, Sandeep Kumar, Matthew Narbutis, Daniel R. Principe
Supplementary Methods, Tables, and Figure Legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9b327db48a40200193a4f49b308b02
https://doi.org/10.1158/0008-5472.22423226
https://doi.org/10.1158/0008-5472.22423226