Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Daniel R Neill"'
Autor:
Angharad E Green, Sian Pottenger, Manal S Monshi, Thomas E Barton, Marie Phelan, Daniel R Neill
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011630 (2023)
Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and bacteraemia and is capable of remarkable phenotypic plasticity, responding rapidly to environmental change. Pneumococcus is a nasopharyngeal commensal, but is responsible
Externí odkaz:
https://doaj.org/article/50d87ba9eb034ff59391986cb61099b8
Publikováno v:
F1000Research, Vol 11 (2022)
The respiratory tract is a compartmentalised and heterogenous environment. The nasopharynx and sinuses of the upper airways have distinct properties from the lungs and these differences may shape bacterial adaptation and evolution. Upper airway niche
Externí odkaz:
https://doaj.org/article/1f11b0ff41484b5da4e2637771e27865
Autor:
Dilip C Badgujar, Anjali Anil, Angharad E Green, Manalee Vishnu Surve, Shilpa Madhavan, Alison Beckett, Ian A Prior, Barsa K Godsora, Sanket B Patil, Prachi Kadam More, Shruti Guha Sarkar, Andrea Mitchell, Rinti Banerjee, Prashant S Phale, Timothy J Mitchell, Daniel R Neill, Prasenjit Bhaumik, Anirban Banerjee
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009016 (2020)
The opportunistic pathogen Streptococcus pneumoniae has dual lifestyles: one of an asymptomatic colonizer in the human nasopharynx and the other of a deadly pathogen invading sterile host compartments. The latter triggers an overwhelming inflammatory
Externí odkaz:
https://doaj.org/article/70810cc3f0074720881ffa86572128e8
Autor:
Yasir Alhamdi, Daniel R Neill, Simon T Abrams, Hesham A Malak, Reham Yahya, Richard Barrett-Jolley, Guozheng Wang, Aras Kadioglu, Cheng-Hock Toh
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004836 (2015)
Streptococcus pneumoniae accounts for more deaths worldwide than any other single pathogen through diverse disease manifestations including pneumonia, sepsis and meningitis. Life-threatening acute cardiac complications are more common in pneumococcal
Externí odkaz:
https://doaj.org/article/45c4d55e61a14cb2b08fbecd8ca27f8a
Autor:
Daniel R Neill, Gemma L Saint, Laura Bricio-Moreno, Joanne L Fothergill, Kevin W Southern, Craig Winstanley, Stephen E Christmas, Joseph R Slupsky, Paul S McNamara, Aras Kadioglu, Brian F Flanagan
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e95892 (2014)
Chronic lung infection with Pseudomonas aeruginosa remains a major cause of mortality and morbidity among individuals with CF. Expression of mediators promoting recruitment and differentiation of B cells, or supporting antibody production is poorly u
Externí odkaz:
https://doaj.org/article/d9baefdc83c6433888940f427d5c849a
Autor:
Eliane Küng, William R Coward, Daniel R Neill, Hesham A Malak, Kathrin Mühlemann, Aras Kadioglu, Markus Hilty, Lucy J Hathaway
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92355 (2014)
The polysaccharide capsule and pneumolysin toxin are major virulence factors of the human bacterial pathogen Streptococcus pneumoniae. Colonization of the nasopharynx is asymptomatic but invasion of the lungs can result in invasive pneumonia. Here we
Externí odkaz:
https://doaj.org/article/cd3b8b184914461289d30ebdc62e225c
Autor:
Daniel R Neill, Vitor E Fernandes, Laura Wisby, Andrew R Haynes, Daniela M Ferreira, Ameera Laher, Natalie Strickland, Stephen B Gordon, Paul Denny, Aras Kadioglu, Peter W Andrew
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002660 (2012)
Streptococcus pneumoniae is an important human pathogen responsible for a spectrum of diseases including pneumonia. Immunological and pro-inflammatory processes induced in the lung during pneumococcal infection are well documented, but little is know
Externí odkaz:
https://doaj.org/article/55f2190d13d3436b97f37e54b2aa69fc
Autor:
Edel A McNeela, Aine Burke, Daniel R Neill, Cathy Baxter, Vitor E Fernandes, Daniela Ferreira, Sarah Smeaton, Rana El-Rachkidy, Rachel M McLoughlin, Andres Mori, Barry Moran, Katherine A Fitzgerald, Jurg Tschopp, Virginie Pétrilli, Peter W Andrew, Aras Kadioglu, Ed C Lavelle
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001191 (2010)
Pneumolysin (PLY) is a key Streptococcus pneumoniae virulence factor and potential candidate for inclusion in pneumococcal subunit vaccines. Dendritic cells (DC) play a key role in the initiation and instruction of adaptive immunity, but the effects
Externí odkaz:
https://doaj.org/article/e10145540ddd48788b803169ff38aeef
Publikováno v:
ACS Applied Materials & Interfaces. 15:20822-20832
Publikováno v:
Am J Respir Crit Care Med
Streptococcus pneumoniae (the pneumococcus) is the leading cause of pneumonia and bacterial meningitis. A number of recent studies indicate an association between the incidence of pneumococcal disease and exposure to air pollution. Although the epide