Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Daniel R Crooks"'
Autor:
Shun Kishimoto, Jeffrey R Brender, Daniel R Crooks, Shingo Matsumoto, Tomohiro Seki, Nobu Oshima, Hellmut Merkle, Penghui Lin, Galen Reed, Albert P Chen, Jan Henrik Ardenkjaer-Larsen, Jeeva Munasinghe, Keita Saito, Kazutoshi Yamamoto, Peter L Choyke, James Mitchell, Andrew N Lane, Teresa WM Fan, W Marston Linehan, Murali C Krishna
Publikováno v:
eLife, Vol 8 (2019)
Metabolic differences among and within tumors can be an important determinant in cancer treatment outcome. However, methods for determining these differences non-invasively in vivo is lacking. Using pancreatic ductal adenocarcinoma as a model, we dem
Externí odkaz:
https://doaj.org/article/55e2be4d50894222ab3e33462c3754bc
Autor:
Suh Young Jeong, Daniel R Crooks, Hayden Wilson-Ollivierre, Manik C Ghosh, Rachid Sougrat, Jaekwon Lee, Sharon Cooperman, James B Mitchell, Carole Beaumont, Tracey A Rouault
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25404 (2011)
Genetic ablation of Iron Regulatory Protein 2 (Irp2, Ireb2), which post-transcriptionally regulates iron metabolism genes, causes a gait disorder in mice that progresses to hind-limb paralysis. Here we have demonstrated that misregulation of iron met
Externí odkaz:
https://doaj.org/article/0c28807b77dd47fd96d4ea38866b81c6
Autor:
Kuanyu Li, Anamika Singh, Daniel R Crooks, Xiaoman Dai, Zhuangzhuang Cong, Liang Pan, Dung Ha, Tracey A Rouault
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12286 (2010)
Friedreich ataxia is an autosomal recessive neurodegenerative disease caused by reduced expression levels of the frataxin gene (FXN) due to expansion of triplet nucleotide GAA repeats in the first intron of FXN. Augmentation of frataxin expression le
Externí odkaz:
https://doaj.org/article/814540eaf74e4c98951a508fc21f21a6
Autor:
Martin Lang, Laura S. Schmidt, Kelli M. Wilson, Christopher J. Ricketts, Carole Sourbier, Cathy D. Vocke, Darmood Wei, Daniel R. Crooks, Youfeng Yang, Benjamin K. Gibbs, Xiaohu Zhang, Carleen Klumpp-Thomas, Lu Chen, Rajarshi Guha, Marc Ferrer, Crystal McKnight, Zina Itkin, Darawalee Wangsa, Danny Wangsa, Amy James, Simone Difilippantonio, Baktir Karim, Francisco Morís, Thomas Ried, Maria J. Merino, Ramaprasad Srinivasan, Craig J. Thomas, W. Marston Linehan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Background MiT-Renal Cell Carcinoma (RCC) is characterized by genomic translocations involving microphthalmia-associated transcription factor (MiT) family members TFE3, TFEB, or MITF. MiT-RCC represents a specific subtype of sporadic RCC tha
Externí odkaz:
https://doaj.org/article/6b0458681f774fc788c19d8f3ed9c6d2
Autor:
Kate Brown, Lisa M. Miller Jenkins, Daniel R. Crooks, Deborah R. Surman, Sharlyn J. Mazur, Yuan Xu, Bhargav S. Arimilli, Ye Yang, Andrew N. Lane, Teresa W-M. Fan, David S. Schrump, W. Marston Linehan, R. Taylor Ripley, Ettore Appella
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
TP53 is the most commonly mutated gene in cancer, and gain-of-function mutations have wide-ranging effects. Efforts to reactivate wild-type p53 function and inhibit mutant functions have been complicated by the variety of TP53 mutations. Identified f
Externí odkaz:
https://doaj.org/article/c07b755597a5468588906ab014a43c40
Publikováno v:
Anal Chem
Biologically important 2-hydroxy carboxylates such as lactate, malate, and 2-hydroxyglutarate exist in two enantiomeric forms that cannot be distinguished under achiral conditions. The D and L (or R, S) enantiomers have different biological origins a
Autor:
Christina M. Fitzsimmons, Mariana D. Mandler, Judith C. Lunger, Dalen Chan, Siddhardha S. Maligireddy, Alexandra C. Schmiechen, Supuni Thalalla Gamage, Courtney Link, Lisa M. Jenkins, Daniel R. Crooks, Jordan L. Meier, W. Marston Linehan, Pedro J. Batista
Metabolic reprogramming is a hallmark of cancer that facilitates changes in many adaptive biological processes. Mutations in the tricarboxylic acid (TCA) cycle enzyme fumarate hydratase (FH) lead to fumarate accumulation and cause hereditary leiomyom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bf2c3915f7b605357eb17693dbf351c
https://doi.org/10.1101/2023.04.10.536262
https://doi.org/10.1101/2023.04.10.536262
Autor:
R. Taylor Ripley, David S. Schrump, Jonathan M. Hernandez, Chuong D. Hoang, Jeremy L. Davis, Leonard M. Neckers, Derek J. Nancarrow, David G. Beer, Laurence P. Diggs, Kaitlin C. McLoughlin, Sichuan Xi, Shaojian Gao, Min-Jung Lee, Sunmin Lee, Jane B. Trepel, Daniel R. Crooks, Emily S. Reardon, Vivek Shukla, Lucas A. McDuffie, Yuan Xu, Kate Brown, Deborah R. Surman, Paul L. Feingold
RNAse Esc2 TXNIP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59cb2352cf6ee8517ba836977219d285
https://doi.org/10.1158/1535-7163.22505272.v1
https://doi.org/10.1158/1535-7163.22505272.v1
Autor:
R. Taylor Ripley, David S. Schrump, Jonathan M. Hernandez, Chuong D. Hoang, Jeremy L. Davis, Leonard M. Neckers, Derek J. Nancarrow, David G. Beer, Laurence P. Diggs, Kaitlin C. McLoughlin, Sichuan Xi, Shaojian Gao, Min-Jung Lee, Sunmin Lee, Jane B. Trepel, Daniel R. Crooks, Emily S. Reardon, Vivek Shukla, Lucas A. McDuffie, Yuan Xu, Kate Brown, Deborah R. Surman, Paul L. Feingold
In 2017, an estimated 17,000 individuals were diagnosed with esophageal adenocarcinoma (EAC), and less than 20% will survive 5 years. Positron emission tomography avidity is indicative of high glucose utilization and is nearly universal in EAC. TXNIP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e340b99ca40389ffa9f98c0fced22dc
https://doi.org/10.1158/1535-7163.c.6538015.v1
https://doi.org/10.1158/1535-7163.c.6538015.v1
Autor:
R. Taylor Ripley, David S. Schrump, Jonathan M. Hernandez, Chuong D. Hoang, Jeremy L. Davis, Leonard M. Neckers, Derek J. Nancarrow, David G. Beer, Laurence P. Diggs, Kaitlin C. McLoughlin, Sichuan Xi, Shaojian Gao, Min-Jung Lee, Sunmin Lee, Jane B. Trepel, Daniel R. Crooks, Emily S. Reardon, Vivek Shukla, Lucas A. McDuffie, Yuan Xu, Kate Brown, Deborah R. Surman, Paul L. Feingold
Cells and Reagents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bce5e7960c6cb1e98e4c8f87eeb3406
https://doi.org/10.1158/1535-7163.22505263
https://doi.org/10.1158/1535-7163.22505263