Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Daniel R, Leff"'
Indocyanine green fluorescence image processing techniques for breast cancer macroscopic demarcation
Autor:
Maria Leiloglou, Martha S. Kedrzycki, Vadzim Chalau, Nicolas Chiarini, Paul T. R. Thiruchelvam, Dimitri J. Hadjiminas, Katy R. Hogben, Faiza Rashid, Rathi Ramakrishnan, Ara W. Darzi, Daniel R. Leff, Daniel S. Elson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Re-operation due to disease being inadvertently close to the resection margin is a major challenge in breast conserving surgery (BCS). Indocyanine green (ICG) fluorescence imaging could be used to visualize the tumor boundaries and help surg
Externí odkaz:
https://doaj.org/article/182d4c90c41f4d4a8af233e350c1cf1e
Autor:
Mary Goble, Virginia Caddick, Ronak Patel, Hemel Modi, Ara Darzi, Felipe Orihuela-Espina, Daniel R. Leff
Publikováno v:
Frontiers in Neuroergonomics, Vol 4 (2023)
IntroductionFunctional near-infrared spectroscopy (fNIRS) is a non-invasive optical neuroimaging technique used to assess surgeons' brain function. The aim of this narrative review is to outline the effect of expertise, stress, surgical technology, a
Externí odkaz:
https://doaj.org/article/bd8bea261aff48078f48088bf55f18e2
Autor:
Dhurka Shanthakumar, Maria Leiloglou, Colm Kelliher, Ara Darzi, Daniel S. Elson, Daniel R. Leff
Publikováno v:
Cancers, Vol 15, Iss 11, p 2884 (2023)
Up to 19% of patients require re-excision surgery due to positive margins in breast-conserving surgery (BCS). Intraoperative margin assessment tools (IMAs) that incorporate tissue optical measurements could help reduce re-excision rates. This review
Externí odkaz:
https://doaj.org/article/1fb120720bc54cf9b55aa7340996c07c
Autor:
Simon D. Dryden, Salzitsa Anastasova, Giovanni Satta, Alex J. Thompson, Daniel R. Leff, Ara Darzi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Urinary tract infection is one of the most common bacterial infections leading to increased morbidity, mortality and societal costs. Current diagnostics exacerbate this problem due to an inability to provide timely pathogen identification. S
Externí odkaz:
https://doaj.org/article/77be74fc3a4f499db43852898daad0af
Publikováno v:
Brain Stimulation, Vol 13, Iss 6, Pp 1834-1841 (2020)
Background: Studies applying transcranial direct-current stimulation (tDCS) to motor regions to enhance surgical skills have observed modest benefits in performance. Early surgical skills acquisition is known to be dependent on the prefrontal cortex
Externí odkaz:
https://doaj.org/article/34fc3b27eaf249d69aadb00682cfd3df
Autor:
Ronak Patel, Amar Rai, Frank Thornton-Wood, Aimee Wilkinson, Ara Darzi, Harsimrat Singh, Daniel R. Leff
Publikováno v:
Brain Stimulation, Vol 14, Iss 3, Pp 616-618 (2021)
Externí odkaz:
https://doaj.org/article/c48dad14346c4bea92897501fb6e3547
Publikováno v:
Data in Brief, Vol 35, Iss , Pp 106905- (2021)
Transcranial direct-current stimulation (tDCS) has previously demonstrated promising effects in improving surgical performance with motor region stimulation [1–4]. However, extensive prior research has revealed an important role of the prefrontal c
Externí odkaz:
https://doaj.org/article/d913deb4374b44509fdface7ccb288d9
Autor:
Amy R. Godden, Aikaterini Micha, Rachel L. O'Connell, Kabir Mohammed, Anna M. Kirby, Paul T.R. Thiruchelvam, Daniel R. Leff, Fiona A. MacNeill, Jennifer E. Rusby, Susan Cleator, Amy Godden, Dorothy Gujral, Dimitri Hadjiminas, Stuart E. James, Aadil Khan, Neill Patani, Gillian Ross, Navita Somaiah, Paul TR Thiruchelvam, Simon H Wood
Publikováno v:
Journal of Plastic, Reconstructive & Aesthetic Surgery. 78:19-28
Autor:
Edward R. St John, Julia Balog, James S. McKenzie, Merja Rossi, April Covington, Laura Muirhead, Zsolt Bodai, Francesca Rosini, Abigail V. M. Speller, Sami Shousha, Rathi Ramakrishnan, Ara Darzi, Zoltan Takats, Daniel R. Leff
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-14 (2017)
Abstract Background Re-operation for positive resection margins following breast-conserving surgery occurs frequently (average = 20–25%), is cost-inefficient, and leads to physical and psychological morbidity. Current margin assessment techniques a
Externí odkaz:
https://doaj.org/article/2f8f974a073943a883917cb74ab7f0c9
Autor:
Zoltan Takats, Daniel R. Leff, Vikneswaran Raj Nagarajan, Corrina Wright, Swathica Kumar, Hutan Ashrafian, Dimitri Hadjiminas, Rishikesh Gandhewar, Natasha Jiwa, Hemali Chauhan
Publikováno v:
Annals of Surgical Oncology
Background Nipple discharge is the third most frequent complaint of women attending rapid diagnostic breast clinics. Nipple smear cytology remains the single most used diagnostic method for investigating fluid content. This study aimed to conduct a s