Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel Qiu"'
Autor:
Christopher Rowbottom, Alicia Pietrasiewicz, Taras Tuczewycz, Richard Grater, Daniel Qiu, Sudarshan Kapadnis, Patrick Trapa
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract Transporters can play a key role in the absorption, distribution, metabolism, and excretion of drugs. Understanding these contributions early in drug discovery allows for more accurate projection of the clinical pharmacokinetics. One method
Externí odkaz:
https://doaj.org/article/103f00bec9d940f988399c1ce77485f6
Autor:
Sudarshan Kapadnis, Patrick Trapa, Richard Grater, Daniel Qiu, Taras Tuczewycz, Christopher Rowbottom, Alicia Pietrasiewicz
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Transporters can play a key role in the absorption, distribution, metabolism, and excretion of drugs. Understanding these contributions early in drug discovery allows for more accurate projection of the clinical pharmacokinetics. One method to assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a2ee10faed30def67aa2b2127bd820
http://europepmc.org/articles/PMC7931226
http://europepmc.org/articles/PMC7931226
Autor:
Alicia Pietrasiewicz, Taras Tuczkewycz, Sudarshan Kapadnis, Richard Grater, Christopher Rowbottom, Daniel Qiu, Doug Burdette, Elvana Viezaj
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f472d5a0170797247e4fe2e3cc05658
https://doi.org/10.1016/j.dmpk.2020.04.132
https://doi.org/10.1016/j.dmpk.2020.04.132
Autor:
Xian-Cheng Jiang, Raj Wadgaonkar, Daniel Qiu, David A. Peake, Hai H. Bui, Kailiu Jiang, Jing Liu, Hongqi Zhang, Guoqing Cao, Tiruneh K. Hailemariam, Zhiqiang Li, Mahua Chakraborty, Ming-Shang Kuo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:850-856
Background— It has been proposed that plasma sphingomyelin (SM) plays a very important role in plasma lipoprotein metabolism and atherosclerosis. Sphingomyelin synthase (SMS) is the last enzyme for SM de novo biosynthesis. Two SMS genes, SMS1 and S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50ad4dc12a32d4a26963d5e34b7714b3
https://doi.org/10.1161/atvbaha.109.185223
https://doi.org/10.1161/atvbaha.109.185223
Autor:
Gerhard, Hannig, Douglas D, Lazarus, Sylvie G, Bernier, Russell M, Karp, Jeanine, Lorusso, Daniel, Qiu, Matthew T, Labenski, Jim D, Wakefield, Charles D, Thompson, William F, Westlin
Publikováno v:
International journal of oncology. 28(4)
Over the past few decades, melanoma has shown the fastest growing incidence rate of all cancers. This malignancy is clinically defined by its potential to rapidly metastasize, and advanced metastatic melanomas are highly resistant to existing therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::212705018d08a4fd526a59fe86fd9986
https://pubmed.ncbi.nlm.nih.gov/16525646
https://pubmed.ncbi.nlm.nih.gov/16525646
Autor:
Riham Carden, Samantha Goodstal, Anderson Clark, Daniel Qiu, Hui Tian, Jamie V. Shaw, Jianguo Ma, Janet Ogden, Hong Zhang
Publikováno v:
Cancer Research. 72:LB-456
MSC2015103 is an orally bio-available, selective, and highly potent small molecule inhibitor of MEK1/2. As a follower to the front-runner MEK inhibitor, pimasertib (MSC1936369/AS703026), a prime objective for the program is to differentiate the two c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb032e298cba48b0ca7783553826fac1
https://doi.org/10.1158/1538-7445.am2012-lb-456
https://doi.org/10.1158/1538-7445.am2012-lb-456