Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Daniel Plano"'
Autor:
Maria Pérez-Araluce, Alessandro Cianciosi, Olalla Iglesias-García, Tomasz Jüngst, Carmen Sanmartín, Íñigo Navarro-Blasco, Felipe Prósper, Daniel Plano, Manuel M. Mazo
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1238 (2024)
The study addresses the challenge of temperature sensitivity in pristine gelatin hydrogels, widely used in biomedical applications due to their biocompatibility, low cost, and cell adhesion properties. Traditional gelatin hydrogels dissolve at physio
Externí odkaz:
https://doaj.org/article/5456ee4b05024801b6faed1f2ee9ce0e
Autor:
Eduardo Angulo-Elizari, Leire Gaviria-Soteras, Irati Zubiri, Sandra Ramos-Inza, Carmen Sanmartin, Daniel Plano
Publikováno v:
Drugs and Drug Candidates, Vol 2, Iss 3, Pp 728-769 (2023)
The Warburg effect (or aerobic glycolysis), which was first described in 1926 by Otto Heinrich Warburg, consists of the change in glucose metabolism in cancer cells. In normal cells, glucose metabolism finalizes in the mitochondria through oxidative
Externí odkaz:
https://doaj.org/article/0b5d1e732c504531b09a1f8b8df39019
Autor:
Nora Astrain-Redin, Niccolò Paoletti, Daniel Plano, Alessandro Bonardi, Paola Gratteri, Andrea Angeli, Carmen Sanmartin, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
In the relentless search for new cancer treatments, organoselenium compounds, and carbonic anhydrase (CA) inhibitors have emerged as promising drug candidates. CA isoforms IX and XII are overexpressed in many types of cancer, and their inhibition is
Externí odkaz:
https://doaj.org/article/7da47668284745f78dcb2e9ab0e624ab
Autor:
Eduardo Angulo-Elizari, Asif Raza, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 272 (2024)
Currently, cancer remains a global health problem. Despite the existence of several treatments, including chemotherapy, immunotherapy, and radiation therapy, the survival rate for most cancer patients, particularly those with metastasis, remains unsa
Externí odkaz:
https://doaj.org/article/098176bff11446df9ff5d299a18bd989
Autor:
Maria Perez-Araluce, Tomasz Jüngst, Carmen Sanmartin, Felipe Prosper, Daniel Plano, Manuel M. Mazo
Publikováno v:
Biomimetics, Vol 9, Iss 1, p 23 (2024)
Oxidative stress is characterized by an increase in reactive oxygen species or a decrease in antioxidants in the body. This imbalance leads to detrimental effects, including inflammation and multiple chronic diseases, ranging from impaired wound heal
Externí odkaz:
https://doaj.org/article/ea7f36909a7d4e228abdb06bc6ea739d
Autor:
Sandra Ramos-Inza, Cesar Aliaga, Ignacio Encío, Asif Raza, Arun K. Sharma, Carlos Aydillo, Nuria Martínez-Sáez, Carmen Sanmartín, Daniel Plano
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1666 (2023)
The introduction of selenium (Se) into organic scaffolds has been demonstrated to be a promising framework in the field of medicinal chemistry. A novel design of nonsteroidal anti-inflammatory drug (NSAID) derivatives based on a bioisosteric replacem
Externí odkaz:
https://doaj.org/article/d34a19d003634a05acc40d2d3b56e764
Publikováno v:
Molecules, Vol 28, Iss 15, p 5845 (2023)
This work describes the design, synthesis, and biological activities of new selenoester derivatives and its homologs thioesters. Thirty-two compounds were developed following an economical synthetic route, achieving small molecules, with structural c
Externí odkaz:
https://doaj.org/article/cab1a412f23e4f82bc1fb6a2013f8207
Autor:
Itziar Galarreta-Rodriguez, Mikel Etxebeste-Mitxeltorena, Esther Moreno, Daniel Plano, Carmen Sanmartín, Saad Megahed, Neus Feliu, Wolfgang J. Parak, Eneko Garaio, Izaskun Gil de Muro, Luis Lezama, Idoia Ruiz de Larramendi, Maite Insausti
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 949 (2023)
In recent years, much effort has been invested into developing multifunctional drug delivery systems to overcome the drawbacks of conventional carriers. Magnetic nanoparticles are not generally used as carriers but can be functionalised with several
Externí odkaz:
https://doaj.org/article/b6a9dc3904f14c1e9b45c9c6c95e865e
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1331 (2023)
Oxidative stress surrounding cancer cells provides them with certain growth and survival advantages necessary for disease progression. In this context, Se-containing molecules have gained attention due to their anticancer and antioxidant activity. In
Externí odkaz:
https://doaj.org/article/968e2e986614404f94f6f29ad21a0354
Autor:
Nora Astrain-Redin, Irene Talavera, Esther Moreno, María J. Ramírez, Nuria Martínez-Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 139 (2023)
Nowadays, oxidative cell damage is one of the common features of cancer and Alzheimer’s disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated strong antioxidant activity, have demonstrated well-established preventive ef
Externí odkaz:
https://doaj.org/article/e910cf08000144dcbd9ce1a4b4028c86