Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Daniel Piehler"'
Autor:
Aline Hillmann, Felicitas Paebst, Walter Brehm, Daniel Piehler, Susanna Schubert, Attila Tárnok, Janina Burk
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218949 (2019)
The immunomodulatory potential of multipotent mesenchymal stromal cells (MSC) provides a basis for current and future regenerative therapies. In this study, we established an approach that allows to address the effects of pro-inflammatory stimulation
Externí odkaz:
https://doaj.org/article/5bebfea281134db0ae981c0456a20e5a
Autor:
Andreas Grahnert, Tina Richter, Daniel Piehler, Maria Eschke, Bianca Schulze, Uwe Müller, Martina Protschka, Gabriele Köhler, Robert Sabat, Frank Brombacher, Gottfried Alber
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87341 (2014)
Cryptococcus neoformans is an opportunistic fungal pathogen that causes lung inflammation and meningoencephalitis in immunocompromised people. Previously we showed that mice succumb to intranasal infection by induction of pulmonary interleukin (IL)-4
Externí odkaz:
https://doaj.org/article/031c667b18dd4953823b2e82aefc9fb4
Autor:
Uwe Müller, Steffen Rossner, Bianca Schulze, Gottfried Alber, Corinna Höfling, Andreas Grahnert, Tina Richter, Maria Eschke, Martina Protschka, Gabriele Köhler, Daniel Piehler
Publikováno v:
European Journal of Immunology. 45:3339-3350
Antiretroviral therapy (ART) has yielded major advances in fighting the HIV pandemic by restoring protective immunity. However, a significant proportion of HIV patients co-infected with the opportunistic fungal pathogen Cryptococcus neoformans parado
Publikováno v:
Veterinary microbiology. 214
Group A porcine rotaviruses are a global threat to animal health in stock breeding. While certain genotypes have shown predominance in other countries, data from Europe's second largest swine population is still scarce. Therefore, porcine rotaviruses
Autor:
Heiner von Buttlar, Gottfried Alber, Bianca Schulze, Gabriele Köhler, Maria Eschke, Daniel Piehler, Tim Sparwasser
Publikováno v:
European Journal of Immunology. 44:3596-3604
The opportunistic fungal pathogen Cryptococcus neoformans causes lung inflammation and fatal meningitis in immunocompromised patients. Regulatory T (Treg) cells play an important role in controlling immunity and homeostasis. However, their functional
Autor:
Felicitas Paebst, Carmen Schroeck, Sandra Heller, Daniel Piehler, Walter Brehm, Janina Burk, Attila Tárnok
Publikováno v:
Cytometry Part A. 85:678-687
Horses are an approved large animal model for therapies of the musculoskeletal system. Especially for tendon disease where cell-based therapy is commonly used in equine patients, the translation of achieved results to human medicine would be a great
Autor:
Daniel Piehler, Gottfried Alber, Tina Richter, Andreas Grahnert, Gabriele Köhler, Maria Eschke, Werner Stenzel
Publikováno v:
Mucosal Immunology. 6:405-414
Interleukin (IL)-33 enhances T helper (Th)2 immunity via its receptor T1/ST2. Infection with the yeast-like pathogen Cryptococcus neoformans is usually controlled by a Th1-mediated immune response. The mechanisms responsible for nonprotective Th2 imm
Autor:
Martina Protschka, Bianca Schulze, Daniel Piehler, Gottfried Alber, Maria Eschke, Laura Heyen, Gabriele Köhler
Publikováno v:
Pathogens and disease. 74(4)
Allergic asthma can be frequently caused and exacerbated by sensitization to ubiquitous fungal allergens associated with pulmonary mucus production, airway hyperresponsiveness and bronchial constriction, resulting in a complex disease that is often d
Autor:
Josephin Held, Maria Eschke, Thomas Kamradt, Frank Brombacher, Gottfried Alber, Andreas Grahnert, Werner Stenzel, Oliver Frey, Gabriele Köhler, Daniel Piehler, Uwe Müller, Tina Richter
Publikováno v:
Mucosal Immunology. 5:299-310
T helper (Th)1 and Th2 cells play decisive roles in the regulation of resistance vs. susceptibility to pulmonary cryptococcosis. To study the function of interleukin (IL)-4 receptor (IL-4R) on Th cells in pulmonary cryptococcosis, we infected mice sp
Autor:
Torsten Schöneberg, Joachim Thiery, Sandra Schmutzler, Antje Wurm, Daniel Piehler, Lars Ritscher, Eva Engemaier, Uwe Müller, Katrin Sangkuhl, Frank W. Albert, Kathrin M. Engel, Herbert Fuhrmann, Angela Schulz, Daniel Teupser, Albert M. Ricken, Doreen Thor, Ines Liebscher, Andreas Reichenbach
Publikováno v:
Journal of Biological Chemistry. 286:2101-2110
The X-chromosomal GPR34 gene encodes an orphan G(i) protein-coupled receptor that is highly conserved among vertebrates. To evaluate the physiological relevance of GPR34, we generated a GPR34-deficient mouse line. GPR34-deficient mice were vital, rep