Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel Pauletti"'
Autor:
Peter M. Grob, Janice R. Brickwood, Cheng-Kon Shih, Maryann Hoermann, Julian Adams, Racheline Schwartz, Daniel Pauletti, Eva David, David A. Erickson, Kevin Barringer, Charles L. Cywin, David Joseph, Susan E. Hattox, Janice M. Klunder, Christopher L. Sorge
Publikováno v:
Journal of Medicinal Chemistry. 41:2960-2971
Like other nonnucleoside inhibitors of HIV-1 reverse transcriptase, the dipyridodiazepinone nevirapine (Viramune, 1) selects for drug resistant variants of HIV-1, both in cell culture and in patients. In particular, the mutation of residue 181 from t
Publikováno v:
Current Protocols in Pharmacology
This unit describes a convenient functional uptake assay for GABA transport into cell lines transiently transfected with GABA transporter-1 (GAT-1) and other GAT isoforms. This facile, homogeneous assay allows for the determination of Km, Vmax, and K
Autor:
Allison L. Zulli, Alexander A. Fedorov, Steven C. Almo, Robert L. Hudkins, Daniel Pauletti, Ted L. Underiner, Lisa D. Aimone, Hong Chang, Thelma S. Angeles, Elena V. Fedorov, Sheryl L. Meyer, Bruce Ruggeri
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(11)
A novel series of 8-(2-tetrahydropyranyl)-12,13-dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazoles (THP-DHI) was synthesized and evaluated as dual TIE-2 and VEGF-R2 receptor tyrosine kinase inhibitors. Development of the structure-activity relationships
Autor:
Bruce D. Dorsey, Karen L. Milkiewicz, Gregory J. Wells, Linda Weinberg, Daniel Pauletti, Torsten Herbertz, Alexander A. Federov, Elena Federov, Sheryl L. Meyer, Ted L. Underiner, Steven C. Almo, Jean Husten, Mark A. Ator
Publikováno v:
The FASEB Journal. 23
Publikováno v:
Analytical Biochemistry. 151:540-546
A computer program was developed for use on an Apple IIe that utilized the parameters developed by Hopp and Woods (T. P. Hopp and K. R. Woods, 1983, Mol. Immunol. 20, 483-489) for predicting the hydrophilic regions of a given protein. This program wi
Autor:
James S. Allan, Ronald C. Kennedy, Gordon R. Dreesman, Myron Essex, Daniel Pauletti, Tak H. Lee, R. D. Henkel
Publikováno v:
Science. 231:1556-1559
In a study performed to determine which regions of the human T-cell lymphotrophic virus type III (HTLV-III) may represent vaccine candidates to prevent the acquired immune deficiency syndrome (AIDS), a synthetic peptide corresponding to amino acid se