Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Daniel P. Tonge"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2020)
Rheumatoid Arthritis (RA) has been increasingly associated with perturbations to the microbial communities that reside in and on the body (the microbiome), in both human and animal studies. To date, such studies have mainly focused on the microbial c
Externí odkaz:
https://doaj.org/article/526f1b0799d74bf0b575f9f86232495e
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225110 (2019)
MethodsThe presence and identity of bacterial and fungal DNA in the synovial fluid of rheumatoid arthritis (RA) patients and healthy control subjects was investigated through amplification and sequencing of the bacterial 16S rRNA gene and fungal inte
Externí odkaz:
https://doaj.org/article/d8c51e2dac764d729f2c2e64efc0dd42
Publikováno v:
International Journal of Biological Macromolecules. 233:123467
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Scientific Reports
Scientific Reports
Asthma is a chronic inflammatory disorder of the airways. Disease presentation varies greatly in terms of cause, development, severity, and response to medication, and thus the condition has been subdivided into a number of asthma phenotypes. There i
Myocardial Infarction Associated Transcript (MIAT) is a subnuclear lncRNA that interferes with alternative splicing and is associated with increased risk of various heart conditions and nervous system tumours. The current study aims to elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3635cfa11407855dc5dc575b86faa5
Publikováno v:
Frontiers in Microbiology, Vol 9 (2019)
Frontiers in Microbiology
Frontiers in Microbiology
The term microbiome describes the genetic material encoding the various microbial populations that inhabit our body. Whilst colonisation of various body niches (e.g. the gut) by dynamic communities of microorganisms is now universally accepted, the e
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225110 (2019)
PLoS ONE
PLoS ONE
The colonisation of specific body sites in contact with the external environment by microorganisms is both well-described and universally accepted, whereas, the existence of microbial evidence in other “classically sterile” locations including th
Publikováno v:
Osteoarthritis and Cartilage. 22(5):609-621
SummaryOsteoarthritis (OA) is an age-related condition and the leading cause of pain, disability and shortening of adult working life in the UK. The incidence of OA increases with age, with 25% of the over 50s population having OA of the knee. Despit
Publikováno v:
ESMO Open. 3:A365-A366
Introduction Of the total human DNA only 1.2% o codes for proteins, with the rest only being transcribed into regulatory RNA, known as non-coding RNA. Long non-coding RNAs (lncRNAs) are non-coding RNAs that have no or limited protein-coding potential
Autor:
Ronald G. Bardsley, Simon W. Jones, Daniel P Tonge, Rose A. Maciewicz, Michael Doherty, Tim Parr
Publikováno v:
Osteoarthritis and Cartilage
Summary Objective To examine whether β2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle can modulate the severity of osteoarthritis (OA) in the rodent meniscectomy (MNX) model. Methods Male Lewis rats were subcutaneously adm