Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Daniel P. Szeto"'
Autor:
David Kimelman, Daniel P. Szeto
Publikováno v:
Development. 131:3751-3760
Combinatorial signaling is an important mechanism that allows the embryo to utilize overlapping signaling pathways to specify different territories. In zebrafish, the Wnt and Bmp pathways interact to regulate the formation of the posterior body. In o
Autor:
Wei Wu, David W. Rose, Anatoli S. Gleiberman, Forrest Liu, Christopher K. Glass, Anna Krones, Ron G. Rosenfeld, Daniel P. Szeto, Michael G. Rosenfeld, Ola Hermanson, Katherine L. Pratt, Zhiyong Wang, Thomas Herman
Publikováno v:
Proceedings of the National Academy of Sciences. 97:13549-13554
A family of p160 coactivators was initially identified based on ligand-dependent interactions with nuclear receptors and thought to function, in part, by recruiting CREB-binding protein/p300 to several classes of transcription factors. One of the p16
Autor:
Daniel P. Szeto, Michael G. Rosenfeld, Forrest Liu, Chijen R. Lin, Shawn M. O'Connell, Chrissa Kioussi, Juan Carlos Izpisúa-Belmonte, Paola Briata
Publikováno v:
Nature. 401:279-282
Pitx1 and Pitx2 are highly homologous, bicoid-related transcription factors. Pitx2 was initially identified as the gene responsible for the human Rieger syndrome, an autosomal dominant condition that causes developmental abnormalities. Pitx2 is asymm
Autor:
Daniel P. Szeto, David Kimelman
Publikováno v:
Nature Cell Biology. 8:305-307
Bone Morphogenetic Protein (Bmp) signalling has a critical function in patterning vertebrate and invertebrate embryos. A key regulator of Bmp signalling is Chordin, which binds Bmps and prevents them from interacting with their receptors. Two new pap
Publikováno v:
Gene. 202:177-186
Ras proteins are involved in a number of signal transduction pathways including the mitogen-activated kinase cascade. Activated MAPKs translocate to the nucleus and phosphorylate transcription factors such as c-myc, TCF and AP-1. Recently, a Ras-resp
Publikováno v:
Proceedings of the National Academy of Sciences. 93:7706-7710
A novel OTX-related homeodomain transcription factor has been identified on the basis of its ability to interact with the transactivation domain of the pituitary-specific POU domain protein, Pit-1. This factor, referred to as P-OTX (pituitary OTX-rel
Autor:
Jeffrey M. Holloway, Kathleen M. Scully, Christopher K. Glass, Daniel P. Szeto, Michael G. Rosenfeld
Publikováno v:
Genes & Development. 9:1992-2006
Transcriptional activation of the prolactin and growth hormone genes, occurring in a cell-specific fashion, requires short-range synergistic interactions between the pituitary-specific POU domain factor Pit-1 and other transcription factors, particul
Publikováno v:
Biomedical Optics Express
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Digital holographic microscopy (DHM) has been applied extensively to in vitro studies of different living cells. In this paper, we present a novel application of an off-axis DHM system to in vivo study of the development of zebrafish embryos. Even wi
Autor:
Jamie L. Seebald, Daniel P. Szeto
Publikováno v:
Developmental biology. 349(1)
Zebrafish eve1, a member of the even-skipped related gene family, is expressed initially in the animal pole of late blastula embryo and subsequently restricted to the ventral mesoderm of the gastrula embryo under the signaling control of bone morphog
Autor:
Daniel P. Szeto, David Kimelman
Publikováno v:
Genesdevelopment. 20(14)
The vertebrate musculature is produced from a visually uniform population of mesodermal progenitor cells (MPCs) that progressively bud off somites populating the trunk and tail. How the MPCs are regulated to continuously release cells into the presom