Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Daniel P. Regan"'
Autor:
Dylan T. Ammons, Leone S. Hopkins, Kathryn E. Cronise, Jade Kurihara, Daniel P. Regan, Steven Dow
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Osteosarcoma (OS) is a heterogeneous, aggressive malignancy of the bone that disproportionally affects children and adolescents. Therapeutic interventions for OS are limited, which is in part due to the complex tumor microenvironment (TME).
Externí odkaz:
https://doaj.org/article/a117ed88309245d08834c3feb15089c6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Soft tissue sarcomas (STS) are a heterogenous group of mesenchymal tumors representing over 50 distinct types with overlapping histological features and non-specific anatomical locations. Currently, localized sarcomas are treated with surger
Externí odkaz:
https://doaj.org/article/72be33ec9b314d078fe5be7813f778cc
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
IntroductionImproving outcomes for oral squamous cell carcinoma (OSCC) patients has been hindered by a lack of effective predictive animal models. Spontaneously occurring canine OSCC could help fill this gap. The objective of this study was to charac
Externí odkaz:
https://doaj.org/article/5307aa3f356a4a569e481c07ddfec441
Autor:
Sunetra Das, Rupa Idate, Daniel P. Regan, Jared S. Fowles, Susan E. Lana, Douglas H. Thamm, Daniel L. Gustafson, Dawn L. Duval
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Sunetra Das et al. combine genetic and immunohistochemistry data to characterize mutation and expression profiles of canine osteosarcoma and its association with clinical outcomes. Their results provide further insight into the pathogenesis and poten
Externí odkaz:
https://doaj.org/article/40f18b0edf8e479584b48c155d3b6eee
Autor:
Benjamin C. Gadomski, Kevin M. Labus, Holly L. Stewart, Katie T. Bisazza, Brad B. Nelson, Christian M. Puttlitz, Kirk C. McGilvray, Daniel P. Regan, Jeremiah T. Easley
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Trauma to the soft tissues of the ankle joint distal syndesmosis often leads to syndesmotic instability, resulting in undesired movement of the talus, abnormal pressure distributions, and ultimately arthritis if deterioration progresses without treat
Externí odkaz:
https://doaj.org/article/69afb2fb86d4444ab8ebec5a9ce8a93c
Autor:
Benjamin C. Gadomski, Kevin M. Labus, Christian M. Puttlitz, Kirk C. McGilvray, Daniel P. Regan, Brad Nelson, Howard B. Seim III, Jeremiah T. Easley
Publikováno v:
JOR Spine, Vol 4, Iss 3, Pp n/a-n/a (2021)
Abstract Background context While the clinical effectiveness of recombinant human Platelet Derived Growth Factor‐B chain homodimer combined with collagen and β‐tricalcium phosphate (rhPDGF‐BB + collagen/β‐TCP) treatment for indications invo
Externí odkaz:
https://doaj.org/article/bee490f818d445bc9c3a30163cffa4e3
Autor:
Dylan T. Ammons, Amanda Guth, Aaron J. Rozental, Jade Kurihara, Angela J. Marolf, Lyndah Chow, John F. Griffin, Rebecca Makii, Brittany MacQuiddy, Mary-Keara Boss, Daniel P. Regan, Chad Frank, Stephanie McGrath, Rebecca A. Packer, Steven Dow
Publikováno v:
Cancer Research Communications. 2:1657-1667
Purpose: Malignant gliomas have a highly immune-suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics. Therefore, the current study evaluated a therapeutic protocol designed to overcome the immu
Autor:
Antonio Cadiz Diaz, Anthony M Cirrincione, Natalie A Schmidt, Marie J Ugo, Maria Celina Amaya Sanchez, Cassandra A. Reimonn, Stefan Wuchty, Adriana D Pellegrini, Leah RK Rude, Leah G Pappalardo, Daniel P Regan, Caitlin Howell, Sybil Hrstka, Surendra Dasari, Thomas S Lisse, Benjamin J Harrison, Mike Xiangxi Xu, Nathan P Staff, Sandra Rieger
Taxanes are chemotherapeutic agents that induce microtubule modifications in cancer cells, resulting in cell cycle modifications and tumor remission. Here we show that paclitaxel, a widely used taxane, also induces microtubule modifications in health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4a1b53cb9de99aea313fbb3da53dc17
https://doi.org/10.1101/2023.05.22.541784
https://doi.org/10.1101/2023.05.22.541784
Autor:
Steven Dow, Rebecca A. Packer, Stephanie McGrath, Chad Frank, Daniel P. Regan, Mary-Keara Boss, Brittany MacQuiddy, Rebecca Makii, John F. Griffin, Lyndah Chow, Angela J. Marolf, Jade Kurihara, Aaron J. Rozental, Amanda Guth, Dylan T. Ammons
Purpose:Malignant gliomas have a highly immune-suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics. Therefore, the current study evaluated a therapeutic protocol designed to overcome the immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35de3fc18082f50224dfe7a057d8b883
https://doi.org/10.1158/2767-9764.c.6551091
https://doi.org/10.1158/2767-9764.c.6551091
Autor:
Daniel V. LaBarbera, Wells A. Messersmith, Daniel L. Gustafson, Aik Choon Tan, Daniel P. Regan, Todd M. Pitts, Paul J. Lunghofer, Dominique A. Ramirez, Adedoyin D. Abraham, Sébastien Rinaldetti, Travis P. Broneske, Laura Pike, Hector Esquer, Qiong Zhou, Joshua M. Abbott
Supplementary Information Section, including: materials, tables, figures, and compound characterization data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1ef5f1ce67232b9d2051043ecb1b5c
https://doi.org/10.1158/1535-7163.22521757
https://doi.org/10.1158/1535-7163.22521757