Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Daniel P. Covey"'
Publikováno v:
Cell Reports, Vol 12, Iss 12, Pp 1997-2008 (2015)
Cocaine is a highly addictive drug that acts upon the brain’s reward circuitry via the inhibition of monoamine uptake. Endogenous cannabinoids (eCB) are lipid molecules released from midbrain dopamine (DA) neurons that modulate cocaine’s effects
Externí odkaz:
https://doaj.org/article/ac148901324643cca13e69d92fcfc4e6
Autor:
Yoki Nakamura, Dilyan I Dryanovski, Yuriko Kimura, Shelley N Jackson, Amina S Woods, Yuko Yasui, Shang-Yi Tsai, Sachin Patel, Daniel P Covey, Tsung-Ping Su, Carl R Lupica
Publikováno v:
eLife, Vol 8 (2019)
Cocaine is an addictive drug that acts in brain reward areas. Recent evidence suggests that cocaine stimulates synthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in midbrain, increasing dopamine neuron activity via disinhibition. Although
Externí odkaz:
https://doaj.org/article/d5672a0035594f02ac50125f313e0254