Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Daniel P. Bulte"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Alzheimer’s disease (AD) is the leading cause of dementia, and its prevalence is increasing and is expected to continue to increase over the next few decades. Because of this, there is an urgent requirement to determine a way to diagnose the diseas
Externí odkaz:
https://doaj.org/article/befe2d02f63b42bab4d8ed19973d5fc7
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Cerebral blood flow (CBF) is an important physiological parameter that can be quantified non-invasively using arterial spin labelling (ASL) imaging. Although most ASL studies are based on single-timepoint strategies, multi-timepoint app
Externí odkaz:
https://doaj.org/article/4486597fdcf1445a83382e410ecb9eac
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Vascular smooth muscle cells (VSMCs) are the key moderators of cerebrovascular dynamics in response to the brain’s oxygen and nutrient demands. Crucially, VSMCs may provide a sensitive biomarker for neurodegenerative pathologies where vasculature i
Externí odkaz:
https://doaj.org/article/98fd2fbc651241a0b2fb72bd4d39f260
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Cerebrovascular reactivity (CVR) is defined as the ability of vessels to alter their caliber in response to vasoactive factors, by means of dilating or constricting, in order to increase or decrease regional cerebral blood flow (CBF). Importantly, CV
Externí odkaz:
https://doaj.org/article/e93073f8c05e412aa5301f5c0f02cc83
Cumulative evidence suggests that impaired cerebrovascular reactivity (CVR), a regulatory response critical for maintaining neuronal health, is amongst the earliest pathological changes in dementia. However, we know little about how CVR is affected b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2692f596dcfbf9e7b1e714e770785b
https://ora.ox.ac.uk/objects/uuid:e92cb9e9-9c97-4da0-bc9d-c8e9dc4e9386
https://ora.ox.ac.uk/objects/uuid:e92cb9e9-9c97-4da0-bc9d-c8e9dc4e9386
Publikováno v:
Journal of Magnetic Resonance Imaging. 56:997-1008
Quantitative imaging studies of the pancreas have often targeted the three main anatomical segments, head, body, and tail, using manual region of interest strategies to assess geographic heterogeneity. Existing automated analyses have implemented who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98eebef7eb7729de97cc61cab90aaf4
https://doi.org/10.1002/jmri.28098
https://doi.org/10.1002/jmri.28098
Vascular smooth muscle cells (VSMCs) are the key moderators of cerebrovascular dynamics in response to the brain’s oxygen and nutrient demands. Crucially, VSMCs may provide a sensitive biomarker for neurodegenerative pathologies where vasculature i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857602051883633c6ad338a4f11e4042
https://doi.org/10.3389/fnins.2022.1010164
https://doi.org/10.3389/fnins.2022.1010164
The change in longitudinal relaxation rate (R1 ) produced by oxygen has been used as a means of inferring oxygenation levels in magnetic resonance imaging in numerous applications. The relationship between oxygen partial pressure (pO2 ) and R1 is lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5ded7d8a041501ad540f8738c99ab5
https://doi.org/10.1002/nbm.4625
https://doi.org/10.1002/nbm.4625
Autor:
L. Durrant, Maria A. Hawkins, Daniel P. Bulte, R. Cooke, C. Jacobs, S.M. Ng, C Qi, Rebecca Muirhead, K.Y. Chu, Victoria Y Strauss, Pradeep S. Virdee, Vicky Goh
Publikováno v:
Clinical Oncology. 32:874-883
Aims The use of diffusion-weighted magnetic resonance imaging (DW-MRI) as a prognostic marker of treatment response would enable early individualisation of treatment. We aimed to quantify the changes in mean apparent diffusion coefficient (ΔADC_mean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbcba5fcb0733716ff4c4e6179b3936
https://doi.org/10.1016/j.clon.2020.09.003
https://doi.org/10.1016/j.clon.2020.09.003
Publikováno v:
Journal of magnetic resonance imaging : JMRIReferences. 55(5)
Background:Under normal physiological conditions, the spin–lattice relaxation rate (R1) in blood is influenced by many factors, including hematocrit, field strength, and the paramagnetic effects of deoxyhemoglobin and dissolved oxygen. In addition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94008eef6952482a1a4cecc996cdc682
https://pubmed.ncbi.nlm.nih.gov/34596290
https://pubmed.ncbi.nlm.nih.gov/34596290