Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Daniel P. Bradley"'
Autor:
Jeffrey Lin, Maryam Zangi, Tanguturi Venkata Narayana Hajay Kumar, Makala Shakar Reddy, Lingala Vijaya Raghava Reddy, Subir Kumar Sadhukhan, Daniel P. Bradley, Brenda Moreira-Walsh, Tiffany C. Edwards, Austin T. O’Dea, John E. Tavis, Marvin J. Meyers, Maureen J. Donlin
Publikováno v:
ACS Omega, Vol 6, Iss 12, Pp 8477-8487 (2021)
Externí odkaz:
https://doaj.org/article/c5271212d8eb4b289be69aa7fe4eb678
Autor:
Daniel P. Bradley, Jean J. Tessier, Susan E. Ashton, John C. Waterton, Zena Wilson, Philip L. Worthington, Anderson J. Ryan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 5, Pp 382-391 (2007)
Magnetic resonance imaging (MRI) can measure the effects of therapies targeting the tumor vasculature and has demonstrated that vascular-damaging agents (VDA) induce acute vascular shutdown in tumors in human and animal models. However, at subtherape
Externí odkaz:
https://doaj.org/article/15be5b2f830449948ad2cb935294b5c3
Autor:
Niall P. Cooke, Madeleine Murray, Lara M. Cassidy, Valeria Mattiangeli, Kenji Okazaki, Kenji Kasai, Takashi Gakuhari, Daniel G. Bradley, Shigeki Nakagome
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110050- (2024)
Summary: Early modern humans lived as hunter-gatherers for millennia before agriculture, yet the genetic adaptations of these populations remain a mystery. Here, we investigate selection in the ancient hunter-gatherer-fisher Jomon and contrast pre- a
Externí odkaz:
https://doaj.org/article/5e928cd60929496e889c549e4192bc74
Autor:
Jessica K. R. Boult, Jennifer Terkelsen, Simon Walker-Samuel, Daniel P. Bradley, Simon P. Robinson
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/c2170cbfe3454b7882212d1f2eddfa8e
Autor:
Niall P. Cooke, Valeria Mattiangeli, Lara M. Cassidy, Kenji Okazaki, Kenji Kasai, Daniel G. Bradley, Takashi Gakuhari, Shigeki Nakagome
Publikováno v:
Evolutionary Human Sciences, Vol 5 (2023)
A tripartite structure for the genetic origin of Japanese populations states that present-day populations are descended from three main ancestors: (1) the indigenous Jomon hunter–gatherers; (2) a Northeast Asian component that arrived during the ag
Externí odkaz:
https://doaj.org/article/313c0105ff9040c6b7a1ae69e039e6d7
Autor:
Colm Elliott, David A Rudko, Douglas L Arnold, Dumitru Fetco, Ahmed M Elkady, David Araujo, Bing Zhu, Arie Gafson, Zhe Tian, Shibeshih Belachew, Daniel P Bradley, Elizabeth Fisher
Publikováno v:
Multiple Sclerosis Journal. 29:680-690
Background: Paramagnetic rim lesions (PRLs) and slowly expanding lesions (SELs) have been posited as markers of chronic active lesions (CALs). Objective: To assess the lesion-level concordance of PRLs and SELs in MS and to characterize changes in bra
Autor:
Siegfried Janz, Brian Van Ness, Joseph B. Bolen, Mark Manfredi, Erik Kupperman, Allison J. Berger, Vishala T. Neppalli, Mary Carsillo, Paul Hales, Ping Li, Olga Tayber, Zhi Li, Michael Pickard, Ray Liu, Matthew D. Silva, Ozlem Subakan, Daniel P. Bradley, Jennifer Terkelsen, Kristen Bano, Jill Donelan, Bret Bannerman, Michael Fitzgerald, Edmund C. Lee
Purpose: The clinical success of the first-in-class proteasome inhibitor bortezomib (VELCADE) has validated the proteasome as a therapeutic target for treating human cancers. MLN9708 is an investigational proteasome inhibitor that, compared with bort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf51cd992431bfa10c2e6773dbd8053
https://doi.org/10.1158/1078-0432.c.6520107
https://doi.org/10.1158/1078-0432.c.6520107
Autor:
Siegfried Janz, Brian Van Ness, Joseph B. Bolen, Mark Manfredi, Erik Kupperman, Allison J. Berger, Vishala T. Neppalli, Mary Carsillo, Paul Hales, Ping Li, Olga Tayber, Zhi Li, Michael Pickard, Ray Liu, Matthew D. Silva, Ozlem Subakan, Daniel P. Bradley, Jennifer Terkelsen, Kristen Bano, Jill Donelan, Bret Bannerman, Michael Fitzgerald, Edmund C. Lee
PDF file - 108K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fd400a1ca08e8405e5d218dd1e0d4b
https://doi.org/10.1158/1078-0432.22444227.v1
https://doi.org/10.1158/1078-0432.22444227.v1
Publikováno v:
Protein Science. 31
Hepatitis B virus (HBV) replicates by protein-primed reverse transcription. It chronically infects >250 million people, and the dominant anti-HBV drugs are nucleos(t)ide analogs targeting the viral polymerase (P). P has four domains, the terminal pro
Autor:
John E. Tavis, Maureen J. Donlin, Jeffrey Lin, Brenda Moreira-Walsh, Tiffany C. Edwards, Lingala Vijaya Raghava Reddy, Makala Shakar Reddy, Marvin J. Meyers, Maryam Zangi, Austin T O'Dea, Daniel P Bradley, Subir Kumar Sadhukhan, Tanguturi Venkata Narayana Hajay Kumar
Publikováno v:
ACS Omega, Vol 6, Iss 12, Pp 8477-8487 (2021)
Opportunistic fungal infections caused by Cryptococcus neoformans are a significant source of mortality in immunocompromised patients. They are challenging to treat because of a limited number of antifungal drugs, and novel and more effective anticry