Výsledky vyhledávání - "Daniel P. Bednarik"

Genomics, Transcriptional Profiling, and Heart Failure

Autor: Kenneth B. Margulies, Daniel P. Bednarik, Daniel L. Dries

Publikováno v: Journal of the American College of Cardiology. 53:1752-1759

Associated with technological progress in deoxyribonucleic acid and messenger ribonucleic acid profiling, advances in basic biology have led to a more complete and sophisticated understanding of interactions among genes, environment, and affected tis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e5aa07b5468b9373a39ceb11cdcdfb
https://doi.org/10.1016/j.jacc.2008.12.064

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Pharmacological Effects of ATI22-107 [2-(2-{2-[2-Chloro-4-(6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenoxy]-acetylamino}-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic Acid Dimethyl Ester)], a Novel Dual Pharmacophore, on Myocyte Calcium Cycling and Contractility

Autor: Steven R. Houser, Albert S. Jung, Kenneth B. Margulies, Geoffrey Mills, Michael P. Quaile, Daniel P. Bednarik

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 312:517-524

Historically, inhibitors of type III phosphodiesterases (PDE-III) have been effective inotropes in mammalian myocardium, but their clinical utility has been limited by adverse events, including arrhythmias that are considered to be due to Ca(2+) over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e44e3007fdc28af26f0981f1ed1385
https://doi.org/10.1124/jpet.104.075895

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Expression and function of periostin-isoforms in bone

Autor: Fayez F. Safadi, Hugh Devlin, Daniel P. Bednarik, Kiyoko Lehmann, Judith Litvin, Abdulhafez Selim, Michael O. Montgomery, Mario C. Rico

Publikováno v: Journal of Cellular Biochemistry. 92:1044-1061

Periostin was originally identified in MC3T3-E1 osteoblast-like cells. We have identified an isoform of periostin referred to as periostin-like-factor (PLF). It is homologous to other proteins such as fasciclin I (fas I), MPB70, βIG-H3, and Algal-CA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996503f1d346b1887cf9940d021b2c1d
https://doi.org/10.1002/jcb.20115

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Mixed messages: transcription patterns in failing and recovering human myocardium

Autor: Kenneth B. Margulies, Carla Cornejo, William A. Craven, Sunil Matiwala, Daniel P. Bednarik, Henrik S. Olsen

Publikováno v: Circulation research. 96(5)

In previous studies, mechanical support of medically refractory hearts with a left ventricular assist device (LVAD) has induced regression of many morphological and functional abnormalities characteristic of failing human hearts. To identify transcri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521bbc9333d7278d87729930cb7a63e1
https://pubmed.ncbi.nlm.nih.gov/15718504

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Development of a novel quantitative assay for the measurement of chloramphenicol acetyl transferase (CAT) mRNA

Autor: Thomas M. Folks, Daniel P. Bednarik, Aftab A. Ansari, Marlyse C. Knuchel, Francois Villinger, Nathaniel F. Chikkala

Publikováno v: Journal of virological methods. 48(2-3)

Most host cells transfected with chloramphenicol acetyl transferase (CAT) expressing plasmids display relatively low levels of constitutive CAT activity. While this is ideal to study factors that enhance gene transcription, decreases in CAT levels ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eaf69e0801bd4c26eda21c20e5e030
https://pubmed.ncbi.nlm.nih.gov/7989447

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DNA Methylation and retrovirus expression

Autor: Daniel P. Bednarik

Publikováno v: DNA Methylation ISBN: 9783034899154

The methylation of cytosine in mammalian DNA has proven to be an enigma to scientists since its discovery more than 30 years ago. There are several apparent roles for the methylation of DNA in eukaryotic cells, the exceptions being Drosophila yeast.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43bca274fef1496d73e8afe5aea85678
https://doi.org/10.1007/978-3-0348-9118-9_13

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Mechanisms of HIV-1 latency

Autor: Daniel P. Bednarik, Thomas M. Folks

Publikováno v: AIDS (London, England). 6(1)

This review describes some of the virus-cell relationships that might contribute to the state of latency observed in HIV infection. Viruses use many mechanisms to persist in their host, and the molecular interactions evoked by the virus and the cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08356889c728e467f04b1fed9f1fd7a1
https://pubmed.ncbi.nlm.nih.gov/1543563

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