Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Daniel P. Gaile"'
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141365 (2015)
Stem cell differentiation involves multiple cascades of transcriptional regulation that govern the cell fate. To study the real-time dynamics of this complex process, quantitative and high throughput live cell assays are required. Herein, we develope
Externí odkaz:
https://doaj.org/article/232458ff2daa4fb0b07877348edbf8d4
Autor:
Ganesh Shankar, Michael R. Rossi, Devin E. McQuaid, Jeffrey M. Conroy, Daniel G. Gaile, John K. Cowell, Norma J. Nowak, Ping Liang
Publikováno v:
Cancer Informatics, Vol 2, Pp 36-43 (2006)
Array-Comparative Genomic Hybridization (aCGH) is a powerful high throughput technology for detecting chromosomal copy number aberrations (CNAs) in cancer, aiming at identifying related critical genes from the affected genomic regions. However, advan
Externí odkaz:
https://doaj.org/article/bcc6800c190a44c8ad47e59ab6d12e88
Autor:
Sai Chen, Shile Zhang, Tingting Jiang, Jennifer Yen, Yupeng He, Ariel Jaimovich, Yvonne Kim, Dustin Ma, Giao Tran, Daniel P. Gaile, Rebecca J. Nagy, Elena Helman, Han-Yu Chuang
Publikováno v:
Cancer Research. 82:3763-3763
Introduction: The ability to detect genome-wide epigenetic changes, such as DNA methylation, has expanded translational applications in oncology settings. Because these changes occur early in carcinogenesis, they can be used for early cancer detectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc259a48f4bc6997b25fc8ad1bbd8d4d
https://doi.org/10.1158/1538-7445.am2022-3763
https://doi.org/10.1158/1538-7445.am2022-3763
Autor:
William W. Greenwald, Yupeng He, Sai Chen, Tingting Jiang, Anton Valouev, Jun Min, Catalin Barbacioru, Daniel P. Gaile, Dustin Ma, Yvonne Kim, Giao Tran, Indira Wu, Ariel Jaimovich, Victoria Raymond, Rebecca J. Nagy, Han-Yu Chuang
Publikováno v:
Cancer Research. 82:3758-3758
Background: Liquid biopsy offers a rapid and non-invasive alternative to tissue biopsy for identifying biomarkers. More recently, its application has broadened to include assessment of early response to therapy (i.e. molecular response) and in the ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d46a5135e7e22152ffcf1e3802c2ca1
https://doi.org/10.1158/1538-7445.am2022-3758
https://doi.org/10.1158/1538-7445.am2022-3758
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Cancer is a major health problem with high mortality rates. In the post-genome era, investigators have access to massive amounts of rapidly accumulating high-throughput data in publicly available databases, some of which are exclusively devoted to ho
Externí odkaz:
https://doaj.org/article/621b76ccb08044fd9789aa1db9836779
Publikováno v:
Statistics & Probability Letters. 130:105-110
In this note we provide a novel straightforward approach to calculating the significance for higher criticism statistics using a general result due to Steck (1971) coined Steck’s determinant. This result allows users to directly assess higher criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58d819e0daddb71ec38bf491463863b5
https://doi.org/10.1016/j.spl.2017.07.009
https://doi.org/10.1016/j.spl.2017.07.009
Publikováno v:
Journal of Leukocyte Biology. 102:1411-1420
Sjögren's syndrome (SS) is an autoimmune disease that often results in diminished exocrine gland function. SS patients also experience systemic disease manifestations, including hypergammaglobulinemia and pulmonary and renal pathoses. MyD88 is a ubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56185199424f573e5e6490d71faa93e
https://doi.org/10.1189/jlb.3a0717-311r
https://doi.org/10.1189/jlb.3a0717-311r
Autor:
Yichen Liang, Lakshmanan Suresh, Daniel P. Gaile, Long Shen, Jeremy Kiripolsky, Quan Zhen Li, Alisa Li, Jill M. Kramer, Yun Lian
Animal models that recapitulate human disease are crucial for the study of Sjogren's Syndrome (SS). While several SS mouse models exist, there are few primary SS (pSS) models that mimic systemic disease manifestations seen in humans. Similar to pSS p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2e36cb2ce3e5befcc74e69dd3beb7c
https://europepmc.org/articles/PMC6082154/
https://europepmc.org/articles/PMC6082154/
Publikováno v:
Statistical applications in genetics and molecular biology. 15(1)
It is often of scientific interest to find a set of genes that may represent an independent functional module or network, such as a functional gene expression module causing a biological response, a transcription regulatory network, or a constellatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9801760a89d62f12a87668181b5f598d
https://pubmed.ncbi.nlm.nih.gov/26756095
https://pubmed.ncbi.nlm.nih.gov/26756095
Publikováno v:
Statistical Applications in Genetics and Molecular Biology. 15
Graphical models have proven to be a valuable tool for connecting genotypes and phenotypes. Structural learning of phenotype-genotype networks has received considerable attention in the post-genome era. In recent years, a dozen different methods have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279bb6aa3a78908e3d04e0fd9354ce47
https://doi.org/10.1515/sagmb-2015-0058
https://doi.org/10.1515/sagmb-2015-0058