Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel P Worrall"'
Autor:
Ryutaro Tanno, Daniel E. Worrall, Enrico Kaden, Aurobrata Ghosh, Francesco Grussu, Alberto Bizzi, Stamatios N. Sotiropoulos, Antonio Criminisi, Daniel C. Alexander
Publikováno v:
NeuroImage, Vol 225, Iss , Pp 117366- (2021)
Deep learning (DL) has shown great potential in medical image enhancement problems, such as super-resolution or image synthesis. However, to date, most existing approaches are based on deterministic models, neglecting the presence of different source
Externí odkaz:
https://doaj.org/article/4d9d593fbc604b66afc012d07795da75
Autor:
Abbas Mohammadi, Behzad Etemad, Xin Zhang, Yijia Li, Gregory J. Bedwell, Radwa Sharaf, Autumn Kittilson, Meghan Melberg, Colline Wong, Jesse Fajnzylber, Daniel P. Worrall, Alex Rosenthal, Hannah Jordan, Nikolaus Jilg, Clarety Kaseke, Francoise Giguel, Xiaodong Lian, Rinki Deo, Elisabeth Gillespie, Rida Chishti, Sara Abrha, Taylor Adams, Abigail Siagian, Peter L. Anderson, Steven G. Deeks, Michael M. Lederman, Sigal Yawetz, Daniel R. Kuritzkes, Mathias D. Lichterfeld, Athe Tsibris, Mary Carrington, Zabrina L. Brumme, Jose R. Castillo-Mancilla, Alan N. Engelman, Gaurav D. Gaiha, Jonathan Z. Li
Publikováno v:
medRxiv
Non-suppressible HIV-1 viremia (NSV) can occur in persons with HIV despite adherence to combination antiretroviral therapy (ART) and in the absence of significant drug resistance. Here, we show that plasma NSV sequences are comprised primarily of lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75847d2fb3febe87ea10a0dca41c2f88
https://europepmc.org/articles/PMC10081408/
https://europepmc.org/articles/PMC10081408/
Autor:
Daniel R. Kuritzkes, Katrina Armstrong, Michael Dougan, Colline Wong, Rebecca M. Baron, Kathryn T. Hall, Edward T. Ryan, Alicja Piechocka-Trocha, Kendyll Coxen, Dusan Hanidziar, Caroline Atyeo, Stephanie Fischinger, Jonathan Z. Li, Athe M. N. Tsibris, Bruce D. Walker, Xu G. Yu, Andrew T. Chan, Lindsey R. Baden, Nikolaus Jilg, Yijia Li, Elizabeth Gillespie, Daniel P Worrall, Galit Alter, Francoise Giguel, Rida Chishti, Keith T. Flaherty, Heather Corry, James Regan, Alexandra Rosenthal, Jesse Fajnzylber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus disease 2019 (COVID-19). Here, we quantify SARS-CoV-2 viral load from participants with a diverse range of COVID-19 disease severi
Autor:
David R. Collins, Michael T. Waring, Gaurav D. Gaiha, Olivia Mae Waring, Todd M. Allen, Bruce D. Walker, Karen A. Power, Jonathan M. Urbach, Musie Ghebremichael, Daniel P Worrall, Elizabeth J. Rossin, James Chodosh, Itai Muzhingi, Chioma Nwonu, Melis N. Anahtar, Christian Landeros, Alicja Piechocka-Trocha, Ruchi M. Newman
Publikováno v:
Science. 364:480-484
Structure-based immunogen design Vaccine design for highly mutable pathogens is hindered by a paucity of conserved immunogenic epitopes. Gaiha et al. employed a structure-based technique using network theory to assign scores to protein structure in o
Autor:
Xu G. Yu, Diane Mathis, Silvia Galván-Peña, Daniel P Worrall, Daniel A Michelson, Juliette Leon, Alicja Piechocka-Trocha, Bruce D. Walker, Christophe Benoist, Kaitavjeet Chowdhary, Jonathan Z. Li, Musie Ghebremichael, Felicia Chen, Liang Yang, Kathryn E Hall, Zachary Manickas-Hill, Brinda Vijaykumar, Angela Magnuson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
bioRxiv
bioRxiv
Significance Regulatory T cells (Tregs) are responsible for restraining excessive inflammation, a hallmark of COVID-19. We identified a striking phenotype in Tregs from patients with severe disease, as well as an interesting role for interleukin (IL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ddf4f9d210a708c6c959f65a15d242
https://doi.org/10.1101/2020.12.11.416180
https://doi.org/10.1101/2020.12.11.416180
Autor:
Gaurav D, Gaiha, Elizabeth J, Rossin, Jonathan, Urbach, Christian, Landeros, David R, Collins, Chioma, Nwonu, Itai, Muzhingi, Melis N, Anahtar, Olivia M, Waring, Alicja, Piechocka-Trocha, Michael, Waring, Daniel P, Worrall, Musie S, Ghebremichael, Ruchi M, Newman, Karen A, Power, Todd M, Allen, James, Chodosh, Bruce D, Walker
Publikováno v:
Science (New York, N.Y.). 364(6439)
Mutationally constrained epitopes of variable pathogens represent promising targets for vaccine design but are not reliably identified by sequence conservation. In this study, we employed structure-based network analysis, which applies network theory