Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Daniel P Regan"'
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200658 (2018)
Pancreatic cancer is the third leading cause of cancer deaths in the United States with more than 53,000 expected to be diagnosed with the disease in 2018. The median survival time after diagnosis is four to six months. The poor survival statistics a
Externí odkaz:
https://doaj.org/article/dfd6affebdec44d3b23e1db87dde52e3
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187552 (2017)
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading forms of cancer related deaths in the United States. With limited treatment options and unreliable diagnostic methods, long-term survival rates following a diagnosis of pancreatic cancer r
Externí odkaz:
https://doaj.org/article/3843ac6ec07f460188fecf56d2b3de6d
Autor:
Dylan T. Ammons, Leone S. Hopkins, Kathryn E. Cronise, Jade Kurihara, Daniel P. Regan, Steven Dow
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Osteosarcoma (OS) is a heterogeneous, aggressive malignancy of the bone that disproportionally affects children and adolescents. Therapeutic interventions for OS are limited, which is in part due to the complex tumor microenvironment (TME).
Externí odkaz:
https://doaj.org/article/a117ed88309245d08834c3feb15089c6
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/ba34439850834459b1ba01f2e381222c
Autor:
Ron C. Gaba, Lobna Elkhadragy, Thomas Pennix, Kyle M. Schachtschneider, Courtni R. Bolt, Aaron Anderson, Shreyan Majumdar, Denise Weber, Herbert E. Whiteley, Daniel P. Regan, Lawrence B. Schook, Bradley P. Sutton
Publikováno v:
Diagnostics, Vol 14, Iss 17, p 1880 (2024)
This pilot study investigated the feasibility of using magnetic resonance elastography (MRE) for the non-invasive detection and quantification of liver fibrosis in the Oncopig cancer model. Seven 8-week-old Oncopigs underwent alcoholic liver fibrosis
Externí odkaz:
https://doaj.org/article/197dca49ea0e450e8b217f70652e1cbb
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Soft tissue sarcomas (STS) are a heterogenous group of mesenchymal tumors representing over 50 distinct types with overlapping histological features and non-specific anatomical locations. Currently, localized sarcomas are treated with surger
Externí odkaz:
https://doaj.org/article/72be33ec9b314d078fe5be7813f778cc
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
IntroductionImproving outcomes for oral squamous cell carcinoma (OSCC) patients has been hindered by a lack of effective predictive animal models. Spontaneously occurring canine OSCC could help fill this gap. The objective of this study was to charac
Externí odkaz:
https://doaj.org/article/5307aa3f356a4a569e481c07ddfec441
Autor:
Sunetra Das, Rupa Idate, Daniel P. Regan, Jared S. Fowles, Susan E. Lana, Douglas H. Thamm, Daniel L. Gustafson, Dawn L. Duval
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Sunetra Das et al. combine genetic and immunohistochemistry data to characterize mutation and expression profiles of canine osteosarcoma and its association with clinical outcomes. Their results provide further insight into the pathogenesis and poten
Externí odkaz:
https://doaj.org/article/40f18b0edf8e479584b48c155d3b6eee
Autor:
Benjamin C. Gadomski, Kevin M. Labus, Christian M. Puttlitz, Kirk C. McGilvray, Daniel P. Regan, Brad Nelson, Howard B. Seim III, Jeremiah T. Easley
Publikováno v:
JOR Spine, Vol 4, Iss 3, Pp n/a-n/a (2021)
Abstract Background context While the clinical effectiveness of recombinant human Platelet Derived Growth Factor‐B chain homodimer combined with collagen and β‐tricalcium phosphate (rhPDGF‐BB + collagen/β‐TCP) treatment for indications invo
Externí odkaz:
https://doaj.org/article/bee490f818d445bc9c3a30163cffa4e3
Autor:
Dylan T. Ammons, Amanda Guth, Aaron J. Rozental, Jade Kurihara, Angela J. Marolf, Lyndah Chow, John F. Griffin, Rebecca Makii, Brittany MacQuiddy, Mary-Keara Boss, Daniel P. Regan, Chad Frank, Stephanie McGrath, Rebecca A. Packer, Steven Dow
Publikováno v:
Cancer Research Communications. 2:1657-1667
Purpose: Malignant gliomas have a highly immune-suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics. Therefore, the current study evaluated a therapeutic protocol designed to overcome the immu