Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Daniel P Nickerson"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)
AbstractPlasmid shuttle vectors capable of replication in both Saccharomyces cerevisiaeEscherichia coliin vitroin vivoin vitro and in vivo
Externí odkaz:
https://doaj.org/article/6a21402381e044a1988ce7294ad61d09
Autor:
Matthew L Schwartz, Daniel P Nickerson, Braden T Lobingier, Rachael L Plemel, Mengtong Duan, Cortney G Angers, Michael Zick, Alexey J Merz
Publikováno v:
eLife, Vol 6 (2017)
Zippering of SNARE complexes spanning docked membranes is essential for most intracellular fusion events. Here, we explore how SNARE regulators operate on discrete zippering states. The formation of a metastable trans-complex, catalyzed by HOPS and i
Externí odkaz:
https://doaj.org/article/0baf4a25cfe943f89e532ac2f3d2c013
Publikováno v:
eLife, Vol 3 (2014)
Secretory and endolysosomal fusion events are driven by SNAREs and cofactors, including Sec17/α-SNAP, Sec18/NSF, and Sec1/Munc18 (SM) proteins. SMs are essential for fusion in vivo, but the basis of this requirement is enigmatic. We now report that,
Externí odkaz:
https://doaj.org/article/37bf2c9442994b53942e5c05f6ea59b8
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Plasmid shuttle vectors capable of replication in both Saccharomyces cerevisiae and Escherichia coli and optimized for controlled modification in vitro and in vivo are a key resource supporting yeast as a premier system for genetics research and synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7226c8dfe5b82fe5a31211263d4a9e7b
https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab336
https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab336
Plasmid shuttle vectors capable of replication in both Saccharomyces cerevisiae and Escherichia coli and optimized for controlled modification in vitro and in vivo are a key resource supporting yeast as a premier system for genetics research and synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55f4118b61062e830351ca40530bdd93
https://doi.org/10.1101/2020.11.03.367219
https://doi.org/10.1101/2020.11.03.367219
Gatekeeper helix activates Golgi SM protein Sly1 and directly mediates close-range vesicle tethering
Autor:
B. M. Delgado, Rachael L. Plemel, Joji Mima, Una Nattermann, Mengtong Duan, Elizabeth A. Miller, Alexey J. Merz, Daniel P. Nickerson, T. Takenaka, A. Lin
The essential Golgi protein Sly1 is a member of the SM (Sec1/mammalian Unc-18) family of SNARE chaperones. Sly1 was originally identified through gain-of-function alleles that bypass requirements for diverse vesicle tethering factors. Employing genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a634574df040a47f697b8a5d5d9717
Autor:
Alexey J. Merz, Daniel B. Carr, Brian M. Wasko, Giang T. Ong, Maitreya J. Dunham, Daniel P. Nickerson, Christopher J. Murakami, Matt Kaeberlein, Anna B. Sunshine, Anna Shemorry
Publikováno v:
Aging Cell
Summary Aneuploidy and aging are correlated; however, a causal link between these two phenomena has remained elusive. Here, we show that yeast disomic for a single native yeast chromosome generally have a decreased replicative lifespan. In addition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3c46662219643d04923cdb4aad88c8
http://europepmc.org/articles/PMC4783355
http://europepmc.org/articles/PMC4783355
Autor:
Adrian Mora, Ariel Lin, Daniel P. Nickerson, Monique A. Quinn, Sean Connolly, Chau Vuong, Beatriz Delgado
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7be5dfb9e65395fbcfaeb32bd61f3e4
https://doi.org/10.1096/fasebj.2020.34.s1.07117
https://doi.org/10.1096/fasebj.2020.34.s1.07117
Autor:
Alexey J. Merz, Daniel P. Nickerson
Publikováno v:
Traffic. 16:1318-1329
Endosomes are transportation nodes, mediating selective transport of soluble and transmembrane cargos to and from the Golgi apparatus, plasma membrane and lysosomes. As endosomes mature to become multivesicular bodies (MVBs), Endosomal Sorting Comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99a61c435690535202fea33003625733
https://doi.org/10.1111/tra.12331
https://doi.org/10.1111/tra.12331
Publikováno v:
Molecular Biology of the Cell
Vps9 is a guanine nucleotide exchange factor that activates Rab5 GTPases in the yeast endolysosomal pathway. Ubiquitin binding by its CUE domain is dispensable for Vps9 function. The CUE domain is shown to target Vps9 to endosomes, supporting a model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b775204cf7c378fafcb76dc9f6f1bbe
https://doi.org/10.1091/mbc.e14-06-1156
https://doi.org/10.1091/mbc.e14-06-1156