Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Daniel P Gelain"'
Autor:
Emily Corneo, Rafael Garbelotto, Gabriele Prestes, Carolina Saibro Girardi, Lucas Santos, Jose Claudio Fonseca Moreira, Daniel Pens Gelain, Glauco A. Westphal, Emil Kupek, Roger Walz, Cristiane Ritter, Felipe Dal-Pizzol
Publikováno v:
Thrombosis Journal, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Because severe acute respiratory syndrome coronarivus 2 (SARS-CoV-2) leads to severe conditions and thrombus formation, evaluation of the coagulation markers is important in determining the prognosis and phenotyping of patients wi
Externí odkaz:
https://doaj.org/article/6b0bc9891da442fcb791aa57dc472a62
Autor:
Francis Jackson de Oliveira Paludo, Matheus Augusto de Bittencourt Pasquali, Amanda Rodrigues de Vargas, Iara Bezerra de Oliveira, Luzia Valberligia Batista Gonçalves, Daniel Pens Gelain, José Cláudio Fonseca Moreira
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 142, Iss , Pp 111993- (2021)
Superoxide dismutase 2 (SOD2) is an antioxidant enzyme that appears phylogenetically conserved. However, functional Sod2 polymorphisms have been studied, and the specific polymorphisms are related to activity alterations of the SOD2 enzyme. An exampl
Externí odkaz:
https://doaj.org/article/e128a3dab8674757ad6ba27d00a0589a
Autor:
Camila Tiefensee Ribeiro, Daniel Oppermann Peixoto, Lucas Santos, Carolina Saibro-Girardi, Pedro Ozorio Brum, Flávio Gabriel Carazza-Kessler, Nauana Somensi, Luiza Marques Prates Behrens, Reykla Ramon Bittencourt, Laíssa Santos Soares, Alexandre Kleber Silveira, Jade de Oliveira, José Cláudio Fonseca Moreira, Juciano Gasparotto, Daniel Pens Gelain
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 14, Iss , Pp 100253- (2021)
HSP70 is one of the main molecular chaperones involved in the cellular stress response. Besides its chaperone action, HSP70 also modulates the immune response. Increased susceptibility to toxic insults in intra- and extracellular environments has bee
Externí odkaz:
https://doaj.org/article/3fbb91b0789d4d929b2039c8f432b21c
Autor:
Andreza Fabro de Bem, Rachel Krolow, Hémelin Resende Farias, Victória Linden de Rezende, Daniel Pens Gelain, José Cláudio Fonseca Moreira, João Miguel das Neves Duarte, Jade de Oliveira
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
The incidence of metabolic disorders, as well as of neurodegenerative diseases—mainly the sporadic forms of Alzheimer’s and Parkinson’s disease—are increasing worldwide. Notably, obesity, diabetes, and hypercholesterolemia have been indicated
Externí odkaz:
https://doaj.org/article/aef0c284cf0745f3a0514ac4e7d95fb6
Autor:
Natália Cabral Souza, Eduardo Natan de Oliveira Nascimento, Iara Bezerra de Oliveira, Hugo Miguel Lisboa Oliveira, Eudeson Gustavo Paiva Santos, Mário Eduardo Rangel Moreira Cavalcanti Mata, Daniel Pens Gelain, José Cláudio Fonseca Moreira, Rodrigo Juliani Siqueira Dalmolin, Matheus Augusto de Bittencourt Pasquali
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 128, Iss , Pp 110277- (2020)
The antioxidant and anti-inflammatory properties of Malpighia emarginata D.C (acerola) and Camellia sinensis L. (green tea) have been studied, particularly as an alternative in medicinal approach for different physio pathological conditions. Here we
Externí odkaz:
https://doaj.org/article/0aad1b87de3a451c92b9455afa6cd973
Autor:
Leonardo da Silva Bittencourt, Carlos Eduardo Schnorr, Daniela Copetti Santos, Diana Carolina Rostirolla, Karla Suzana Moresco, Pedro Ozório, Moara Rodrigues Mingori, Luana Heinfarth, Daniel Pens Gelain, José Cláudio Fonseca Moreira
Publikováno v:
Journal of Functional Foods, Vol 65, Iss , Pp 103733- (2020)
Previous studies have reported that acrolein, may exert harmful effects on the brain. However, information regarding the neuroprotective properties of guarana against acrolein is not available. Due to the lack of research, we initiated the current st
Externí odkaz:
https://doaj.org/article/009d7336686849bcb5f44feb605fa7ba
Autor:
Juciano Gasparotto, Camila Tiefensee Ribeiro, Rafael Calixto Bortolin, Nauana Somensi, Thallita Kelly Rabelo, Alice Kunzler, Natália Cabral Souza, Matheus Augusto de Bittencourt Pasquali, José Claudio Fonseca Moreira, Daniel Pens Gelain
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The receptor for advanced glycation endproducts (RAGE) is a pattern-recognition receptor associated with inflammation in most cell types. RAGE up-regulates the expression of proinflammatory mediators and its own expression via activation of
Externí odkaz:
https://doaj.org/article/ffb3602eb03b464ba25e09c194a671bc
Autor:
Nauana Somensi, Pedro Ozorio Brum, Vitor de Miranda Ramos, Juciano Gasparotto, Alfeu Zanotto-Filho, Diana Carolina Rostirolla, Maurilio da Silva Morrone, José Claudio Fonseca Moreira, Daniel Pens Gelain
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 6, Pp 2507-2522 (2017)
Background/Aims: Heat shock protein 70 (HSP70) has been recently described with extracellular actions, where it is actively released in inflammatory conditions. Acting as DAMPs (damage associated molecular pattern), extracellular HSP70 (eHSP70) inter
Externí odkaz:
https://doaj.org/article/946e983d6840408e9d617c9b52a43cdb
Autor:
Hamilton Malfussi, Iara Vidigal Santana, Juciano Gasparotto, Cassia Righy, Cristiane Damiani Tomasi, Daniel Pens Gelain, Fernando A. Bozza, Roger Walz, Felipe Dal-Pizzol, Cristiane Ritter
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
The presence of autoantibodies against neuronal cell surface or synaptic proteins and their relationship to autoimmune encephalitis have recently been characterized. These autoantibodies have been also reported in other pathologic conditions; however
Externí odkaz:
https://doaj.org/article/25d520a79fb44ab9b42422a291cd57d5
Autor:
Grace Anne A. Dória, Anderson R. Santos, Leonardo S. Bittencourt, Rafael C. Bortolin, Paula P. Menezes, Bruno S. Vasconcelos, Rebeca O. Souza, Maria José V. Fonseca, Alan Diego C. Santos, Shanmugam Saravanan, Francilene A. Silva, Daniel P. Gelain, José Cláudio F. Moreira, Ana Paula N. Prata, Lucindo J. Quintans-Júnior, Adriano A. S. Araújo
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 11699-11718 (2015)
Remirea maritima is a tropical plant with a reticulated root system belonging to the family Cyperaceae, also known to have biologically active secondary metabolites. However, very few data on R. maritima’s biological actions are available and there
Externí odkaz:
https://doaj.org/article/da09498fcabb4d41942ffd452536fdb0