Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Daniel P Carter"'
Autor:
Hilary Bower, Mubarak El Karsany, Abd Alhadi Adam Hussein Adam, Mubarak Ibrahim Idriss, Ma'aaza Abasher Alzain, Mohamed Elamin Ahmed Alfakiyousif, Rehab Mohamed, Iman Mahmoud, Omer Albadri, Suha Abdulaziz Alnour Mahmoud, Orwa Ibrahim Abdalla, Mawahib Eldigail, Nuha Elagib, Ulrike Arnold, Bernardo Gutierrez, Oliver G Pybus, Daniel P Carter, Steven T Pullan, Shevin T Jacob, Tajeldin Mohammedein Abdallah, Benedict Gannon, Tom E Fletcher
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009387 (2021)
BackgroundThe public health impact of Chikungunya virus (CHIKV) is often underestimated. Usually considered a mild condition of short duration, recent outbreaks have reported greater incidence of severe illness, fatality, and longer-term disability.
Externí odkaz:
https://doaj.org/article/cc6646bf211b4466b1167ed4beff6a79
Autor:
Jayne E. Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J. Gifford, Jamie I. Fletcher, Chengyuan Xue, Nisitha Jayatilleke, Firoozeh Salehzadeh, Laura D. Gamble, Jourdin R. C. Rouaen, Daniel R. Carter, Helen Forgham, Eric O. Sekyere, Joanna Keating, Georgina Eden, Sophie Allan, Stephanie Alfred, Frances K. Kusuma, Ashleigh Clark, Hannah Webber, Amanda J. Russell, Antoine de Weck, Benjamin T. Kile, Martina Santulli, Piergiuseppe De Rosa, Emmy D. G. Fleuren, Weiman Gao, Lorna Wilkinson-White, Jason K. K. Low, Joel P. Mackay, Glenn M. Marshall, Douglas J. Hilton, Federico M. Giorgi, Jan Koster, Giovanni Perini, Michelle Haber, Murray D. Norris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract MYCN oncogene amplification is frequently observed in aggressive childhood neuroblastoma. Using an unbiased large-scale mutagenesis screen in neuroblastoma-prone transgenic mice, we identify a single germline point mutation in the transcript
Externí odkaz:
https://doaj.org/article/ee532e0c05a8415d9de099a04d9f475c
Autor:
Giulia Maria Porro, Italo Lorandi, Xueying Liu, Kazunori Kataoka, Giuseppe Battaglia, Daniel Gonzalez-Carter
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Current strategies to identify ligands for brain delivery select candidates based on preferential binding to cell-membrane components (CMC) on brain endothelial cells (EC). However, such strategies generate ligands with inherent brain specif
Externí odkaz:
https://doaj.org/article/5e295844e27441a8a876f87cb589ebb9
Autor:
Brian Rice, Ana Maria Buller, Delia Boccia, Cesar Bazan, Rafael Miranda, Ximena Cea, Rodrigo Laro, Miguel Fontes, Rosalie Hayes, Mariken de Wit, Daniel J. Carter, Alexandra Plowright, Matthew Chadwick, Mitzy Gafos
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background The global mining industry is an important partner in advancing the 2030 Agenda for Sustainable Development. In 2018, Anglo American plc published their Sustainable Mining Plan, containing a goal for improving health and wellbeing
Externí odkaz:
https://doaj.org/article/0f9cfb18edb54d259877dc0a9ab00abf
Autor:
Lei Zhai, Anushree Balachandran, Rebecca Larkin, Janith A. Seneviratne, Sylvia A. Chung, Amit Lalwani, Shoma Tsubota, Dominik Beck, Kenji Kadomatsu, Anneleen Beckers, Kaat Durink, Katleen De Preter, Frank Speleman, Michelle Haber, Murray D. Norris, Alexander Swarbrick, Belamy B. Cheung, Glenn M. Marshall, Daniel R. Carter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15571 (2023)
MYCN amplification occurs in approximately 20–30% of neuroblastoma patients and correlates with poor prognosis. The TH-MYCN transgenic mouse model mimics the development of human high-risk neuroblastoma and provides strong evidence for the oncogeni
Externí odkaz:
https://doaj.org/article/d559d7b12c324b4bb5d46cc7f02c2a1c
Autor:
Brian Rice, Delia Boccia, Daniel J. Carter, Renay Weiner, Lebohang Letsela, Mariken de Wit, Rebecca Pursell, Michael Jana, Ana Maria Buller, Mitzy Gafos
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background The global mining industry has an opportunity to mobilize resources to advance progress against the Sustainable Development Goals (SDGs). In 2018, the Anglo-American Group outlined aspirations for mining host communities to meet t
Externí odkaz:
https://doaj.org/article/c2af8fc5006c4270aeac1830a6a99842
Autor:
Xiaojun Yuan, Janith A. Seneviratne, Shibei Du, Ying Xu, Yijun Chen, Qianya Jin, Xuanxuan Jin, Anushree Balachandran, Shihao Huang, Yanli Xu, Yue Zhai, Liumei Lu, Mengjie Tang, Yushuang Dong, Belamy B. Cheung, Glenn M. Marshall, Weiyang Shi, Daniel R. Carter, Chao Zhang
Publikováno v:
Cell Reports, Vol 41, Iss 1, Pp 111455- (2022)
Summary: Peripheral neuroblastic tumors (PNTs) represent a spectrum of neural-crest-derived tumors, including neuroblastoma, ganglioneuroblastoma, and ganglioneuroma. Malignant cells in PNTs are theorized to interconvert between adrenergic/noradrener
Externí odkaz:
https://doaj.org/article/8ca94de93e7e43f69b531c80e9140074
Autor:
Quentin Van Thillo, Jolien De Bie, Janith A. Seneviratne, Sofie Demeyer, Sofia Omari, Anushree Balachandran, Vicki Zhai, Wai L. Tam, Bram Sweron, Ellen Geerdens, Olga Gielen, Sarah Provost, Heidi Segers, Nancy Boeckx, Glenn M. Marshall, Belamy B. Cheung, Kiyotaka Isobe, Itaru Kato, Junko Takita, Timothy G. Amos, Ira W. Deveson, Hannah McCalmont, Richard B. Lock, Ethan P. Oxley, Maximilian M. Garwood, Ross A. Dickins, Anne Uyttebroeck, Daniel R. Carter, Jan Cools, Charles E. de Bock
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
SPI1 fusion genes in T-cell acute lymphoblastic leukemia (T-ALL) are commonly found with co-occurring NRAS mutations. Here, the authors show that the combination of these oncogenes is necessary to drive T-ALL in a murine model and that the oncogenic
Externí odkaz:
https://doaj.org/article/097bfb27edca4477bb37a09172ff1f71
Autor:
Jack M. Crook, Ivana Murphy, Daniel P. Carter, Steven T. Pullan, Miles Carroll, Richard Vipond, Andrew A. Cunningham, Diana Bell
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The source of the COVID-19 pandemic is unknown, but the natural host of the progenitor sarbecovirus is thought to be Asian horseshoe (rhinolophid) bats. We identified and sequenced a novel sarbecovirus (RhGB01) from a British horseshoe bat,
Externí odkaz:
https://doaj.org/article/a1019b0ed0ad43a695e4866f7a28a6e9
Autor:
Zsuzsanna Nagy, Janith A. Seneviratne, Maxwell Kanikevich, William Chang, Chelsea Mayoh, Pooja Venkat, Yanhua Du, Cizhong Jiang, Alice Salib, Jessica Koach, Daniel R. Carter, Rituparna Mittra, Tao Liu, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Neuroblastoma (NB) is often driven by MYCN amplification. Here, the authors show that the most frequent genetic lesion, gain of 17q21-ter in NB leads to overexpression of ALYREF, which forms a complex with MYCN, regulating MYCN stability via the deub
Externí odkaz:
https://doaj.org/article/9758c1cb40dc42078fa4de67f4245a4d