SEDA 2024 update: enhancing the SEquence DAtaset builder for seamless integration into automated data analysis pipelines

Autor: Miguel Reboiro-Jato, Daniel Pérez-Rodríguez, Miguel José Da Silva, David Vila-Fernández, Cristina P. Vieira, Jorge Vieira, Hugo López-Fernández

Publikováno v: BMC Bioinformatics, Vol 25, Iss 1, Pp 1-9 (2024)

Abstract Background The initial version of SEDA assists life science researchers without programming skills with the preparation of DNA and protein sequence FASTA files for multiple bioinformatics applications. However, the initial version of SEDA la

Externí odkaz: https://doaj.org/article/ba9b47851a8b41a6b6c4b4f4579d89a0

MyBrain-Seq: A Pipeline for MiRNA-Seq Data Analysis in Neuropsychiatric Disorders

Autor: Daniel Pérez-Rodríguez, Roberto Carlos Agís-Balboa, Hugo López-Fernández

Publikováno v: Biomedicines, Vol 11, Iss 4, p 1230 (2023)

High-throughput sequencing of small RNA molecules such as microRNAs (miRNAs) has become a widely used approach for studying gene expression and regulation. However, analyzing miRNA-Seq data can be challenging because it requires multiple steps, from

Externí odkaz: https://doaj.org/article/c2804862a0e74bab9975f1d0884a7ec5

MiRNA Differences Related to Treatment-Resistant Schizophrenia

Autor: Daniel Pérez-Rodríguez, Maria Aránzazu Penedo, Tania Rivera-Baltanás, Tonatiuh Peña-Centeno, Susanne Burkhardt, Andre Fischer, José M. Prieto-González, José Manuel Olivares, Hugo López-Fernández, Roberto Carlos Agís-Balboa

Publikováno v: International journal of molecular sciences 24(3), 1891 (2023). doi:10.3390/ijms24031891 special issue: "Identifying the Molecular Mechanisms of Psychiatric Disorders to Define New Therapeutic Targets"
International Journal of Molecular Sciences; Volume 24; Issue 3; Pages: 1891

Schizophrenia (SZ) is a serious mental disorder that is typically treated with antipsychotic medication. Treatment-resistant schizophrenia (TRS) is the condition where symptoms remain after pharmacological intervention, resulting in long-lasting func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ba69f450dfc8ade13645a629f6878d
https://doi.org/10.3390/ijms24031891

Microglia: The Real Foe in HIV-1-Associated Neurocognitive Disorders?

Autor: Carlos Fernández-Pereira, David Alonso-Crespo, Roberto Carlos Agís-Balboa, Tania Rivera-Baltanás, Ana Borrajo López, José M. Olivares, Maria Aránzazu Penedo, Daniel Pérez-Rodríguez

Publikováno v: Biomedicines
Biomedicines, Vol 9, Iss 925, p 925 (2021)

The current use of combined antiretroviral therapy (cART) is leading to a significant decrease in deaths and comorbidities associated with human immunodeficiency virus type 1 (HIV-1) infection. Nonetheless, none of these therapies can extinguish the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af81f8b67d2131ad282db789fef06fc
http://europepmc.org/articles/PMC8389599

Application of miRNA-seq in neuropsychiatry: A methodological perspective

Autor: Daniel Pérez-Rodríguez, Roberto Carlos Agís-Balboa, Hugo López-Fernández

Publikováno v: Computers in Biology and Medicine. 135:104603

MiRNAs are emerging as key molecules to study neuropsychiatric diseases. However, despite the large number of methodologies and software for miRNA-seq analyses, there is little supporting literature for researchers in this area. This review focuses o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5408e3206835a936ab2c3c4b0ad20a
https://doi.org/10.1016/j.compbiomed.2021.104603