Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Daniel P, Furkert"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 154 (2024)
Positive allosteric modulators (PAMs) of the cannabinoid CB1 receptor (CB1) offer potential therapeutic advantages in the treatment of neuropathic pain and addiction by avoiding the adverse effects associated with orthosteric CB1 activation. Here, mo
Externí odkaz:
https://doaj.org/article/3caa23ad45eb4c9bb86cba9efa8739a6
Autor:
Bin Lin, Benjamin J. Daniels, Martin J. Middleditch, Daniel P. Furkert, Margaret A. Brimble, Jessie Bong, Jonathan M. Stephens, Kerry M. Loomes
Publikováno v:
ACS Omega, Vol 5, Iss 15, Pp 8858-8866 (2020)
Externí odkaz:
https://doaj.org/article/79d3b7300beb4bb8aeaff4b699d92f01
Publikováno v:
Organic Letters. 25:2895-2900
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44246ac53762d2c116b81c61bbb3139e
https://doi.org/10.1021/acs.orglett.3c00902
https://doi.org/10.1021/acs.orglett.3c00902
Publikováno v:
Organic & Biomolecular Chemistry. 21:1222-1234
This work details a novel approach to access the [7,6]-spirocyclic fragment of 13-desmethyl spirolide C. A more efficient synthesis of the key lactam dienophile is reported, and a comprehensive investigation of the Diels-Alder reaction is included.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f38970b6aa5f5b88a9398542a6171f1b
https://doi.org/10.1039/d2ob01992b
https://doi.org/10.1039/d2ob01992b
Autor:
Genevieve L. Evans, Daniel P. Furkert, Nacim Abermil, Preeti Kundu, Katrina M. de Lange, Emily J. Parker, Margaret A. Brimble, Edward N. Baker, J. Shaun Lott
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 1019-1029 (2017)
There are twenty-five published structures of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (Mtb-AnPRT) that use the same crystallization protocol. The structures include protein complexed with natural and alternative substrates,
Externí odkaz:
https://doaj.org/article/5c6539f806014fd3a63a51b4a3d201bc
Publikováno v:
Chemistry – A European Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa63d77a6516ff001995dff6fd299a13
https://doi.org/10.1002/chem.202301235
https://doi.org/10.1002/chem.202301235
Autor:
Scott A. Lawrence, Hannah F. Robinson, Daniel P. Furkert, Margaret A. Brimble, Monica L. Gerth
Publikováno v:
Molecules, Vol 26, Iss 7, p 1819 (2021)
Phytophthora is a genus of microorganisms that cause devastating dieback and root-rot diseases in thousands of plant hosts worldwide. The economic impact of Phytophthora diseases on crops and native ecosystems is estimated to be billions of dollars p
Externí odkaz:
https://doaj.org/article/c7639e4f1e36402b80656aeb06333eae
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2325-2342 (2016)
Rising resistance to current clinical antibacterial agents is an imminent threat to global public health and highlights the demand for new lead compounds for drug discovery. One such potential lead compound, the peptide antibiotic teixobactin, was re
Externí odkaz:
https://doaj.org/article/c57ef8f6762f46118891477488a80c57
Publikováno v:
Asian Journal of Organic Chemistry. 10:2869-2875
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b37f9593c9f0fe6b8f188cd0547020d2
https://doi.org/10.1002/ajoc.202100445
https://doi.org/10.1002/ajoc.202100445
Publikováno v:
ChemCatChem. 12:5759-5771
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d7999d0c2a7701a38591e42fe33c157
https://doi.org/10.1002/cctc.202001139
https://doi.org/10.1002/cctc.202001139