Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Daniel P, Cahill"'
Autor:
Syeda Maheen Batool, Ana K. Escobedo, Tiffaney Hsia, Emil Ekanayake, Sirena K. Khanna, Austin S. Gamblin, Hui Zheng, Johan Skog, Julie J. Miller, Anat O. Stemmer-Rachamimov, Daniel P. Cahill, Leonora Balaj, Bob S. Carter
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Glioma represents the most common central nervous system neoplasm in adults. Current classification scheme utilizes molecular alterations, particularly IDH1.R132H, to stratify lesions into distinct prognostic groups. Identification of the si
Externí odkaz:
https://doaj.org/article/d6294d2e360d4950ac3797fa6fafc364
Autor:
Tikvah K. Hayes, Elisa Aquilanti, Nicole S. Persky, Xiaoping Yang, Erica E. Kim, Lisa Brenan, Amy B. Goodale, Douglas Alan, Ted Sharpe, Robert E. Shue, Lindsay Westlake, Lior Golomb, Brianna R. Silverman, Myshal D. Morris, Ty Running Fisher, Eden Beyene, Yvonne Y. Li, Andrew D. Cherniack, Federica Piccioni, J. Kevin Hicks, Andrew S. Chi, Daniel P. Cahill, Jorg Dietrich, Tracy T. Batchelor, David E. Root, Cory M. Johannessen, Matthew Meyerson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The epidermal growth factor receptor, EGFR, is frequently activated in lung cancer and glioblastoma by genomic alterations including missense mutations. The different mutation spectra in these diseases are reflected in divergent responses to
Externí odkaz:
https://doaj.org/article/0edde2f4b771457398e829246efe16d1
Autor:
Kensuke Tateishi, Yohei Miyake, Taishi Nakamura, Hiromichi Iwashita, Takahiro Hayashi, Akito Oshima, Hirokuni Honma, Hiroaki Hayashi, Kyoka Sugino, Miyui Kato, Kaishi Satomi, Satoshi Fujii, Takashi Komori, Tetsuya Yamamoto, Daniel P. Cahill, Hiroaki Wakimoto
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract In IDH-mutant astrocytoma, IDH2 mutation is quite rare and biological mechanisms underlying tumor progression in IDH2-mutant astrocytoma remain elusive. Here, we report a unique case of IDH2 mutant astrocytoma, CNS WHO grade 3 that developed
Externí odkaz:
https://doaj.org/article/bbe8b7243e7e40e29827ce3987261302
Autor:
Atsushi M. Takahashi, Jitendra Sharma, David O. Guarin, Julie Miller, Hiroaki Wakimoto, Daniel P. Cahill, Yi-Fen Yen
Publikováno v:
Journal of Magnetic Resonance Open, Vol 16, Iss , Pp 100123- (2023)
We report several inductively coupled RF coil designs that are very easy to construct, produce high signal-to-noise ratio (SNR) and high spatial resolution while accommodating life support, anesthesia and monitoring in small animals. Inductively coup
Externí odkaz:
https://doaj.org/article/34f6af13f1754c5eb6d75c801352888f
Autor:
Tikvah K. Hayes, Elisa Aquilanti, Nicole S. Persky, Xiaoping Yang, Erica E. Kim, Lisa Brenan, Amy B. Goodale, Douglas Alan, Ted Sharpe, Robert E. Shue, Lindsay Westlake, Lior Golomb, Brianna R. Silverman, Myshal D. Morris, Ty Running Fisher, Eden Beyene, Yvonne Y. Li, Andrew D. Cherniack, Federica Piccioni, J. Kevin Hicks, Andrew S. Chi, Daniel P. Cahill, Jorg Dietrich, Tracy T. Batchelor, David E. Root, Cory M. Johannessen, Matthew Meyerson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/c60cde2e831e452ca04b334e2136cd27
Autor:
Priscilla K. Brastianos, Albert E. Kim, Anita Giobbie-Hurder, Eudocia Quant Lee, Nancy Wang, April F. Eichler, Ugonma Chukwueke, Deborah A. Forst, Isabel C. Arrillaga-Romany, Jorg Dietrich, Zachary Corbin, Jennifer Moliterno, Joachim Baehring, Michael White, Kevin W. Lou, Juliana Larson, Magali A. de Sauvage, Kathryn Evancic, Joana Mora, Naema Nayyar, Jay Loeffler, Kevin Oh, Helen A. Shih, William T. Curry, Daniel P. Cahill, Fred G. Barker, Elizabeth R. Gerstner, Sandro Santagata
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
Abstract High-grade meningiomas are associated with neuro-cognitive morbidity and have limited treatments. High-grade meningiomas harbor an immunosuppressive tumor microenvironment (TME) and programmed death-ligand 1 (PD-L1) expression may contribute
Externí odkaz:
https://doaj.org/article/151a61114ef3419098315fb6862b5008
Autor:
Sanjay M. Prakadan, Christopher A. Alvarez-Breckenridge, Samuel C. Markson, Albert E. Kim, Robert H. Klein, Naema Nayyar, Andrew W. Navia, Benjamin M. Kuter, Kellie E. Kolb, Ivanna Bihun, Joana L. Mora, Mia Solana Bertalan, Brian Shaw, Michael White, Alexander Kaplan, Jackson H. Stocking, Marc H. Wadsworth, Eudocia Q. Lee, Ugonma Chukwueke, Nancy Wang, Megha Subramanian, Denisse Rotem, Daniel P. Cahill, Viktor A. Adalsteinsson, Jeffrey W. Miller, Ryan J. Sullivan, Scott L. Carter, Priscilla K. Brastianos, Alex K. Shalek
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Leptomeningeal disease (LMD) is a serious complication of metastatic solid tumors with a poor prognosis. Here, by using single-cell RNA sequencing of cerebrospinal fluid, the authors report genomic and immune correlates of response to immunotherapy i
Externí odkaz:
https://doaj.org/article/687017c072604770afffff35e85435f2
Autor:
Priscilla K. Brastianos, Matthew R. Strickland, Eudocia Quant Lee, Nancy Wang, Justine V. Cohen, Ugonma Chukwueke, Deborah Anne Forst, April Eichler, Beth Overmoyer, Nancy U. Lin, Wendy Y. Chen, Aditya Bardia, Dejan Juric, Ibiayi Dagogo-Jack, Michael D. White, Jorg Dietrich, Naema Nayyar, Albert E. Kim, Christopher Alvarez-Breckenridge, Maura Mahar, Joana L. Mora, Brian V. Nahed, Pamela S. Jones, Helen A. Shih, Elizabeth R. Gerstner, Anita Giobbie-Hurder, Scott L. Carter, Kevin Oh, Daniel P. Cahill, Ryan J. Sullivan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Leptomeningeal metastases from solid tumors are a rare complication with a very poor prognosis. Here the authors report the efficacy and safety of combined ipilimumab and nivolumab in patients with leptomeningeal carcinomatosis.
Externí odkaz:
https://doaj.org/article/b04f3eeb51ed4432b18eeaf9f4a73076
Autor:
Tareq A. Juratli, Insa Prilop, Felix C. Saalfeld, Sylvia Herold, Matthias Meinhardt, Carina Wenzel, Silke Zeugner, Daniela E. Aust, Fred G. Barker, Daniel P. Cahill, Priscilla K. Brastianos, Sandro Santagata, Gabriele Schackert, Thomas Pinzer
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/1e680a3127184b6993515635f457bbbd
Autor:
Erik A. Williams, Sandro Santagata, Hiroaki Wakimoto, Ganesh M. Shankar, Fred G. Barker, Radwa Sharaf, Abhinav Reddy, Phoebe Spear, Brian M. Alexander, Jeffrey S. Ross, Priscilla K. Brastianos, Daniel P. Cahill, Shakti H. Ramkissoon, Tareq A. Juratli
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-10 (2020)
Abstract Background Genomic studies of high-grade/progressive meningiomas have reported a heterogeneous mutation spectrum, identifying few recurrently mutated genes. Most studies have been underpowered to detect genomic subclasses of aggressive menin
Externí odkaz:
https://doaj.org/article/35b60a8f99044ddca1ea6cdff6638aa2