Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Daniel P, Aalberts"'
Autor:
Leticia Pollo-Oliveira, Nick K Davis, Intekhab Hossain, Peiying Ho, Yifeng Yuan, Pedro Salguero García, Cécile Pereira, Shane R Byrne, Jiapeng Leng, Melody Sze, Crysten E Blaby-Haas, Agnieszka Sekowska, Alvaro Montoya, Thomas Begley, Antoine Danchin, Daniel P Aalberts, Alexander Angerhofer, John Hunt, Ana Conesa, Peter C Dedon, Valérie de Crécy-Lagard
Publikováno v:
Metallomics : integrated biometal science. 14(9)
Queuosine (Q) is a conserved hypermodification of the wobble base of tRNA containing GUN anticodons but the physiological consequences of Q deficiency are poorly understood in bacteria. This work combines transcriptomic, proteomic and physiological s
Autor:
Daniel P. Aalberts
Publikováno v:
Entropy, Vol 13, Iss 11, Pp 1958-1966 (2011)
The free energy of an RNA fold is a combination of favorable base pairing and stacking interactions competing with entropic costs of forming loops. Here we show how loop entropy, surprisingly, can promote tertiary order. A general formula for the fre
Externí odkaz:
https://doaj.org/article/01bf81f1b76d48e9b0f23f6c23e24a14
Publikováno v:
Journal of Molecular Biology. 434:167578
Expression of mRNA is often regulated by the binding of a small RNA (miRNA, snoRNA, siRNA). While the pairing contribution to the net free energy is well parameterized and can be computed in O(N) time, the cost of removing pre-existing mRNA secondary
Publikováno v:
Microbial Biotechnology
Microbial Biotechnology, Wiley, 2019, 12 (1), pp.44-47. ⟨10.1111/1751-7915.13338⟩
Microbial Biotechnology, Wiley, 2019, 12 (1), pp.44-47. ⟨10.1111/1751-7915.13338⟩
Recombinant proteins are essential for biotechnology. Here we review some of the key points for improving the production of heterologous proteins, and what can be the future of the field.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9e420379ee663cc332c09889e67ccc
https://hal.archives-ouvertes.fr/hal-02324955
https://hal.archives-ouvertes.fr/hal-02324955
Publikováno v:
Biophysical Journal. 118:548a
Synonymous codon choices at the beginning of genes optimize 5′ RNA structures for enhanced translation initiation, but less is known about mechanisms that drive codon optimization downstream within the gene. To understand what determines codon choi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b02ddfa6e958b98e466581b295f02ce
https://europepmc.org/articles/PMC5318996/
https://europepmc.org/articles/PMC5318996/
Autor:
Gaetano T. Montelione, W. Nicholson Price, Mayank Valecha, Reka Letso, Thomas Acton, Kam Ho Wong, Grégory Boël, Helen Neely, Min Su, Daniel P. Aalberts, Jon D. Luff, Rong Xiao, John F. Hunt, John K. Everett
Publikováno v:
Nature
Nature, Nature Publishing Group, 2016, 529 (7586), pp.358-363. ⟨10.1038/nature16509⟩
Nature, Nature Publishing Group, 2016, 529 (7586), pp.358-363. ⟨10.1038/nature16509⟩
Degeneracy in the genetic code, which enables a single protein to be encoded by a multitude of synonymous gene sequences, has an important role in regulating protein expression, but substantial uncertainty exists concerning the details of this phenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601f0018c7fed5372993b756df6c7323
https://hal.archives-ouvertes.fr/hal-02104423
https://hal.archives-ouvertes.fr/hal-02104423
Autor:
Daniel P. Aalberts, Hans F. Stabenau
Publikováno v:
Physica A: Statistical Mechanics and its Applications. 389:2981-2986
We propose a simple physical mechanism to explain the ultrafast first step of vision, a photoinduced cis to trans rotation of retinal. In the ground state, the torsional stability of π bonds is countered by Coulomb interactions acting between the π
Autor:
Daniel P. Aalberts
Publikováno v:
Entropy (Basel, Switzerland)
Entropy
Volume 13
Issue 11
Pages: 1958-1966
Entropy, Vol 13, Iss 11, Pp 1958-1966 (2011)
Entropy
Volume 13
Issue 11
Pages: 1958-1966
Entropy, Vol 13, Iss 11, Pp 1958-1966 (2011)
The free energy of an RNA fold is a combination of favorable base pairing and stacking interactions competing with entropic costs of forming loops. Here we show how loop entropy, surprisingly, can promote tertiary order. A general formula for the fre
Publikováno v:
Biophysical Journal. 84:3212-3217
DNA beacons are short single-stranded chains which can form closed hairpin shapes through complementary base pairing at their ends. Contrary to the common polymer theory assumption that only their loop length matters, experiments show that their clos