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of 9
pro vyhledávání: '"Daniel O'Donovan"'
Autor:
Saatviga Sudhahar, Bugra Ozer, Jiakang Chang, Wayne Chadwick, Daniel O’Donovan, Aoife Campbell, Emma Tulip, Neil Thompson, Ian Roberts
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Explaining predictions for drug repositioning with biological knowledge graphs is a challenging problem. Graph completion methods using symbolic reasoning predict drug treatments and associated rules to generate evidence representing the the
Externí odkaz:
https://doaj.org/article/a3a9e69ec3314471b6379af78138ae76
Autor:
Damian M. Bailey, George A. Rose, Daniel O'Donovan, Dafydd Locker, Ian R. Appadurai, Richard G. Davies, Richard J. Whiston, Mohamad Bashir, Michael H. Lewis, Ian M. Williams
Publikováno v:
Aorta (Stamford, Conn.). 10(5)
Background In the United Kingdom, the most common surgical approach for repair of open abdominal aortic aneurysms (AAAs) is transperitoneal (TP). However, retroperitoneal (RP) approach is favored in those with more complex vascular anatomy often requ
Autor:
Daniel O'Donovan, Axel T. Brunger, Ian Stokes-Rees, Stephen C. Blacklow, Yunsun Nam, Gunnar F. Schröder, Piotr Sliz
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
The deformable elastic network (DEN) method for reciprocal-space crystallographic refinement improves crystal structures, especially at resolutions lower than 3.5 Å. The DEN web service presented here intends to provide structural biologists with ac
Autor:
Masahiro Shirakawa, Tsutomu Mikawa, Daniel O'Donovan, Ernest D. Laue, Brian O. Smith, Teppei Ikeya, Takashi Tanaka, Takahiro Shirai, Yuichiro Hourai, Yutaka Ito, Jumpei Hamatsu, Wayne Boucher, Masaki Mishima
Publikováno v:
Journal of the American Chemical Society. 135(5)
Recent developments in in-cell NMR techniques have allowed us to study proteins in detail inside living eukaryotic cells. In order to complement the existing protocols, and to extend the range of possible applications, we introduce a novel approach f
Publikováno v:
eScience
The SBGrid Science Portal provides multi-modal access to computational infrastructure, data storage, and data analysis tools for the structural biology community. It incorporates features not previously seen in cyberinfrastructure science gateways. I
Autor:
Stephen C. Blacklow, Thomas E. Wales, Sung Hee Choi, Yunsun Nam, John R. Engen, Daniel O'Donovan, Piotr Sliz
Publikováno v:
Structure (London, England : 1993). 20(2)
Summary The Notch intracellular domain (NICD) forms a transcriptional activation complex with the DNA-binding factor CSL and a transcriptional co-activator of the Mastermind family (MAML). The "RAM" region of NICD recruits Notch to CSL, facilitating
Autor:
Daniel O'Donovan, Pascal O'Connor
Publikováno v:
SPIE Proceedings.
The advent of low-cost charge coupled device (CCD) cameras offers an alternative approach to the construction of visual inspection systems in the manufacturing industry. An array of such cameras may be arranged such that a panoramic view may be achie
Autor:
Daniel O'Donovan, Edward Leete
Publikováno v:
Journal of the American Chemical Society. 85:461-463
A mixture of Di-tryptophan- BETA -C14 and DL-tryptophan- BETA H3 was fed to barley seedlings and resulted in the formation of radioactive gramine, which was labeled solely on the methylene group of the side chain with C14 and tritium. The ratio of C1
Conference
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