Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Daniel Nemecek"'
Autor:
Lumir Krejci, Mário Špírek, Fletcher E. Bain, Daniel Nemecek, Sarah R. Hengel, Jana Prochazkova, Liping Yu, Brandon G Koch, Maria Spies, Jarmila Mlcouskova, Barbora Stefanovie, Fedor Nikulenkov
Publikováno v:
Nucleic Acids Research
The proper repair of deleterious DNA lesions such as double strand breaks prevents genomic instability and carcinogenesis. In yeast, the Rad52 protein mediates DSB repair via homologous recombination. In mammalian cells, despite the presence of the R
Publikováno v:
Journal of Virology. 86:11616-11624
Bacteriophage ϕ6 is a double-stranded RNA (dsRNA) virus whose genome is packaged sequentially as three single-stranded RNA (ssRNA) segments into an icosahedral procapsid which serves as a compartment for genome replication and transcription. The pro
Autor:
James H. Hurley, Juan S. Bonifacino, Alasdair C. Steven, Christina Schindler, Rodolfo Ghirlando, William J. Smith, Hyung Ho Lee, Daniel Nemecek
Publikováno v:
Journal of Biological Chemistry. 287:5882-5890
BLOC-1 (biogenesis of lysosome-related organelles complex-1) is critical for melanosome biogenesis and has also been implicated in neurological function and disease. We show that BLOC-1 is an elongated complex that contains one copy each of the eight
Autor:
Naiqian Cheng, Leonard Mindich, Jian Qiao, Alasdair C. Steven, Daniel Nemecek, J. Bernard Heymann
Publikováno v:
Journal of Molecular Biology. 414:260-271
The initial assembly product of bacteriophage ϕ6, the procapsid, undergoes major structural transformation during the sequential packaging of its three segments of single-stranded RNA. The procapsid, a compact icosahedrally symmetric particle with d
Publikováno v:
Journal of Structural Biology. 171:389-396
Assembly of dsRNA bacteriophage phi6 involves packaging of the three mRNA strands of the segmented genome into the procapsid, an icosahedrally symmetric particle with recessed vertices. The hexameric packaging NTPase (P4) overlies these vertices, and
Publikováno v:
Biopolymers. 79:1-8
Structural features of mismatched base pairs were studied on four nonamer hybrid duplexes formed between the 5'-d(GTGATATGC)-3' complement and its 5'-r(GCAUNUCAC)-3' (N = A, C, G, U) counterparts. This oligonucleotide set is considered a model molecu
Publikováno v:
Biopolymers. 74:115-119
A set of four 9-mer oligonucleotide duplexes formed between the 5′-GCATNTCAC-3′, N=A,C,T,G, and the 5′-GTGATATGC-3′ complement has been proposed as a model system for the investigation of novel oligonucleotide analogues (candidates for antise