Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Daniel Nava-Rodrigues"'
Autor:
Johann S. deBono, Jeffrey R. Harris, Saskia M. Burm, Adriaan Vanderstichele, Mischa A. Houtkamp, Saida Aarass, Ruth Riisnaes, Ines Figueiredo, Daniel Nava Rodrigues, Rossitza Christova, Siel Olbrecht, Hans W. M. Niessen, Sigrid R. Ruuls, Danita H. Schuurhuis, Jeroen J. Lammerts van Bueren, Esther C. W. Breij, Ignace Vergote
Publikováno v:
Cancer Reports, Vol 6, Iss 2, Pp n/a-n/a (2023)
Abstract Background Elevated tissue factor (TF) expression, although restricted in normal tissue, has been reported in multiple solid cancers, and expression has been associated with poor prognosis. This manuscript compares TF expression across vario
Externí odkaz:
https://doaj.org/article/0e98ad51ac3645c9bafd82abf01d3681
Autor:
María Dolores Fenor de la Maza, Khobe Chandran, Jan Rekowski, Irene M. Shui, Bora Gurel, Emily Cross, Suzanne Carreira, Wei Yuan, Daniel Westaby, Susana Miranda, Ana Ferreira, George Seed, Mateus Crespo, Ines Figueiredo, Claudia Bertan, Veronica Gil, Ruth Riisnaes, Adam Sharp, Daniel Nava Rodrigues, Pasquale Rescigno, Nina Tunariu, Xiao Qiao Liu, Razvan Cristescu, Charles Schloss, Christina Yap, Johann S. de Bono
Publikováno v:
European Urology Oncology. 5:659-667
Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease in which molecular stratification is needed to improve clinical outcomes. The identification of predictive biomarkers can have a major impact on the care of these pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b3b7049add6ef405b58e662904596b
https://doi.org/10.1016/j.euo.2022.04.004
https://doi.org/10.1016/j.euo.2022.04.004
Autor:
Andreas Heindl, Adnan Mujahid Khan, Daniel Nava Rodrigues, Katherine Eason, Anguraj Sadanandam, Cecilia Orbegoso, Marco Punta, Andrea Sottoriva, Stefano Lise, Susana Banerjee, Yinyin Yuan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cancer cells can actively engage in overcoming microenvironmental constraints such as tissue stiffness through adapting their shapes; however it is unclear how microenvironmental cells shape cancer nuclear morphology in human tumors in situ. Here the
Externí odkaz:
https://doaj.org/article/80aafabf129a42f2a86063973bcb2266
Autor:
Adam G. Sowalsky, Ines Figueiredo, Rosina T. Lis, Ilsa Coleman, Bora Gurel, Denisa Bogdan, Wei Yuan, Joshua W. Russo, John R. Bright, Nichelle C. Whitlock, Shana Y. Trostel, Anson T. Ku, Radhika A. Patel, Lawrence D. True, Jonathan Welti, Juan M. Jimenez-Vacas, Daniel Nava Rodrigues, Ruth Riisnaes, Antje Neeb, Cynthia T. Sprenger, Amanda Swain, Scott Wilkinson, Fatima Karzai, William L. Dahut, Steven P. Balk, Eva Corey, Peter S. Nelson, Michael C. Haffner, Stephen R. Plymate, Johann S. de Bono, Adam Sharp
Publikováno v:
Clin Cancer Res
Purpose: Therapies targeting the androgen receptor (AR) have improved the outcome for patients with castration-sensitive prostate cancer (CSPC). Expression of the constitutively active AR splice variant-7 (AR-V7) has shown clinical utility as a predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb056e552b2301f63ba44bb13d249e4
https://doi.org/10.1158/1078-0432.ccr-22-0851
https://doi.org/10.1158/1078-0432.ccr-22-0851
Autor:
Johann S. de Bono, Yvette Drew, Juanita S. Lopez, Bristi Basu, Ruth Plummer, Udai Banerji, Christopher J. Lord, Andrew Foxley, Justin P.O. Lindemann, Paul Rugman, Emma Hall, Laura Finneran, Karen E. Swales, Shaun Decordova, Florence I. Raynaud, Ruth Ruddle, Nicholas C. Turner, Heidrun Gevensleben, Neha Chopra, Nina Tunariu, Alison Turner, Mona Parmar, Ruth Matthews, Sarah Ward, Daniel Nava Rodrigues, Ines Figueiredo, Susana Miranda, Ruth Riisnaes, Rowan Miller, Desamparados Roda, Suzanne Carreira, Joline S.J. Lim, Stephen J. Pettitt, Vasiliki Michalarea, Rebecca Kristeleit, Timothy A. Yap
Preclinical studies have demonstrated synergy between PARP and PI3K/AKT pathway inhibitors in BRCA1 and BRCA2 (BRCA1/2)–deficient and BRCA1/2-proficient tumors. We conducted an investigator-initiated phase I trial utilizing a prospective intrapatie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e33adbfd1faf3496d00cefbd4e1d17
https://doi.org/10.1158/2159-8290.c.6547955.v1
https://doi.org/10.1158/2159-8290.c.6547955.v1
Autor:
Johann S. de Bono, Yvette Drew, Juanita S. Lopez, Bristi Basu, Ruth Plummer, Udai Banerji, Christopher J. Lord, Andrew Foxley, Justin P.O. Lindemann, Paul Rugman, Emma Hall, Laura Finneran, Karen E. Swales, Shaun Decordova, Florence I. Raynaud, Ruth Ruddle, Nicholas C. Turner, Heidrun Gevensleben, Neha Chopra, Nina Tunariu, Alison Turner, Mona Parmar, Ruth Matthews, Sarah Ward, Daniel Nava Rodrigues, Ines Figueiredo, Susana Miranda, Ruth Riisnaes, Rowan Miller, Desamparados Roda, Suzanne Carreira, Joline S.J. Lim, Stephen J. Pettitt, Vasiliki Michalarea, Rebecca Kristeleit, Timothy A. Yap
Supplementary Tables 1-7; Supplementary Figures 1-2; Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b42dc1c2ce5b8015019651ef216b42
https://doi.org/10.1158/2159-8290.22535825
https://doi.org/10.1158/2159-8290.22535825
Autor:
Johann S. de Bono, Suzanne Carreira, Arul M. Chinnaiyan, Emma Hall, Christopher J. Lord, Alexa Gillman, Diletta Bianchini, Nina Tunariu, Adam Sharp, Zafeiris Zafeiriou, Pasquale Rescigno, Semini Sumanasuriya, Ruth Riisnaes, Ines Figueiredo, Mateus Crespo, Matthew Clarke, Mark Atkin, Claudia Bertan, Gunther Boysen, Daniel Nava Rodrigues, George Seed, Penny Flohr, Berni Ebbs, Gemma Fowler, Shahneen Sandhu, Dan R. Robinson, David Dolling, Raquel Perez-Lopez, Susana Miranda, Nuria Porta, Helen Mossop, Wei Yuan, Joaquin Mateo, Jane Goodall
Plots showing percentage changes in total cfDNA concentration for each patient at weeks 4 and 8 of treatment, compared to same-patient baseline value. The left plot includes non-responding patients and the right plot includes patients who responded t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ee078515e95060afc2ec08c429ee52
https://doi.org/10.1158/2159-8290.22531838.v1
https://doi.org/10.1158/2159-8290.22531838.v1
Autor:
Johann S. de Bono, Leon W.M.M. Terstappen, Nikolas H. Stoecklein, Kiki Andree, Joost Swennenhuis, Rui P. Neves, Lucy Hamilton, Deirdre Moloney, Joanne Hunt, Zafeiris Zafeiriou, Pasquale Rescigno, Diletta Bianchini, Suzanne Carreira, Gunther Boysen, Jane Goodall, Adam Sharp, Daniel Nava Rodrigues, Ruth Riisnaes, Ines Figueiredo, Claudia Bertan, Rita Pereira, Ana Ferreira, Alan Mackay, Wei Yuan, Susana Miranda, Penny Flohr, Berni Ebbs, Gemma Fowler, Niven Mehra, Rob Chandler, Mariane Fontes, Mateus Crespo, Veronica Gil, Semini Sumanasuriya, George Seed, Maryou B. Lambros
Clinical data: a) Summary of prior treatments of all 14 patients prior to apheresis. b) A histogram presenting the lymphocyte and neutrophil counts (x109/L) in peripheral blood pre- and post-apheresis procedures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde2210292300e5e165a72cb15410ce9
https://doi.org/10.1158/1078-0432.22469411.v1
https://doi.org/10.1158/1078-0432.22469411.v1
Autor:
Johann S. de Bono, Adam Sharp, Stephen R. Plymate, Christopher J. Schofield, Bissan Al-Lazikani, Andrea Alimonti, Nina Tunariu, Suzanne Carreira, Maryou B. Lambros, Susana Miranda, Mateus Crespo, Lorenzo Buroni, Veronica S. Gil, Rossitza Christova, Bora Gurel, Akane Kawamura, Martine Abboud, Marc A. Moesser, Md. Saiful Islam, Anthony Tumber, Patrizio Di Micco, Takuma Uo, Soojin Kim, Juan M. Jiménez-Vacas, Daniel Nava Rodrigues, Ruth Riisnaes, Ana Ferreira, Rita Pereira, Ines Figueiredo, Wei Yuan, Antje J. Neeb, Jonathan Welti, Alec Paschalis
Supplementary Figure from JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc8fda216d27d81ffbe7ee2ca708e6
https://doi.org/10.1158/0008-5472.22427590.v1
https://doi.org/10.1158/0008-5472.22427590.v1
Autor:
Johann S. de Bono, Leon W.M.M. Terstappen, Nikolas H. Stoecklein, Kiki Andree, Joost Swennenhuis, Rui P. Neves, Lucy Hamilton, Deirdre Moloney, Joanne Hunt, Zafeiris Zafeiriou, Pasquale Rescigno, Diletta Bianchini, Suzanne Carreira, Gunther Boysen, Jane Goodall, Adam Sharp, Daniel Nava Rodrigues, Ruth Riisnaes, Ines Figueiredo, Claudia Bertan, Rita Pereira, Ana Ferreira, Alan Mackay, Wei Yuan, Susana Miranda, Penny Flohr, Berni Ebbs, Gemma Fowler, Niven Mehra, Rob Chandler, Mariane Fontes, Mateus Crespo, Veronica Gil, Semini Sumanasuriya, George Seed, Maryou B. Lambros
Baseline characteristics of study patients (n=14). *All values given are at time of apheresis unless otherwise specified. â^§The Eastern Cooperative Oncology Group (ECOG) performance status score ranges from 0 to 5, with 0 indicating no symptoms an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4023f9f26ab16f0be183c8b9c7b25dab
https://doi.org/10.1158/1078-0432.22469393
https://doi.org/10.1158/1078-0432.22469393