Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Daniel N. Cox"'
Autor:
Erin N. Lottes, Feyza Ciger, Shatabdi Bhattacharjee, Emily A. Timmins, Benoit Tete, Tommy Tran, Jais Matta, Atit A. Patel, Daniel N. Cox
Publikováno v:
Cells, Vol 13, Iss 12, p 1029 (2024)
The development of cell-type-specific dendritic arbors is integral to the proper functioning of neurons within their circuit networks. In this study, we examine the regulatory relationship between the cytosolic chaperonin CCT, key insulin pathway gen
Externí odkaz:
https://doaj.org/article/e965ea5123ea44cebe87ec4c2ddc1557
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108243- (2023)
Summary: Neuropeptides are packed into large dense core vesicles (LDCVs) that are transported from the soma out into their processes. Limited information exists regarding mechanisms regulating LDCV trafficking, particularly during challenges to bodil
Externí odkaz:
https://doaj.org/article/8086a6849ee34278a14732ec6ae1838f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14638 (2023)
Temperature sensation involves thermosensitive TRP (thermoTRP) and non-TRP channels. Drosophila larval Class III (CIII) neurons serve as the primary cold nociceptors and express a suite of thermoTRP channels implicated in noxious cold sensation. How
Externí odkaz:
https://doaj.org/article/0b7cc4a31cd943868d9aaab4fbec8541
Autor:
Shatabdi Bhattacharjee, Erin N. Lottes, Sumit Nanda, Andre Golshir, Atit A. Patel, Giorgio A. Ascoli, Daniel N. Cox
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Uncovering molecular mechanisms regulating dendritic diversification is essential to understanding the formation and modulation of functional neural circuitry. Transcription factors play critical roles in promoting dendritic diversity and here, we id
Externí odkaz:
https://doaj.org/article/dbd647b406444016abc97f8817014f36
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101510- (2022)
Summary: Here, we outline protocols to study cold acclimation in Drosophila from a neurobiological perspective, starting with fictive cold acclimation using a custom-built optogenetics-housing apparatus we call the OptoBox. We also provide detailed s
Externí odkaz:
https://doaj.org/article/2b4726ec2d83490e80e415c2586181ad
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Calcium (Ca2+) plays a pivotal role in modulating neuronal-mediated responses to modality-specific sensory stimuli. Recent studies in Drosophila reveal class III (CIII) multidendritic (md) sensory neurons function as multimodal sensors regulating dis
Externí odkaz:
https://doaj.org/article/041e5e2f4b394e718aadcd0920267572
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Coding noxious cold signals, such as the magnitude and rate of temperature change, play essential roles in the survival of organisms. We combined electrophysiological and computational neuroscience methods to investigate the neural dynamics of Drosop
Externí odkaz:
https://doaj.org/article/3f49ba1595c2460bb003f4bfb775bdf0
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6741 (2023)
Dendritic morphology underlies the source and processing of neuronal signal inputs. Morphology can be broadly described by two types of geometric characteristics. The first is dendrogram topology, defined by the length and frequency of the arbor bran
Externí odkaz:
https://doaj.org/article/28f388b186dd45a682398102ad2eb831
Autor:
Shatabdi Bhattacharjee, Eswar Prasad R. Iyer, Srividya Chandramouli Iyer, Sumit Nanda, Myurajan Rubaharan, Giorgio A. Ascoli, Daniel N. Cox
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6344 (2023)
Dendrites are the primary points of sensory or synaptic input to a neuron and play an essential role in synaptic integration and neural function. Despite the functional importance of dendrites, relatively less is known about the underlying mechanisms
Externí odkaz:
https://doaj.org/article/5987d1de36c9469aa7e2ffd3bc8bc3bd
Autor:
Ferdinand Althammer, Hildebrando Candido Ferreira-Neto, Myurajan Rubaharan, Ranjan K. Roy, Atit A. Patel, Daniel N. Cox, Javier E. Stern
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)
Abstract Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, de
Externí odkaz:
https://doaj.org/article/5dc52cfc25e549bd962955445536ae20