Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Daniel Mulhern"'
Autor:
Joao A. Paulo, Sean A. Beausoleil, Daniel Mulhern, Steven P. Gygi, Ailan Guo, Anthony Possemato
Publikováno v:
Journal of Proteome Research. 16:1506-1514
A comprehensive view of protein phosphorylation remains an unmet challenge in the field of cell biology. Mass spectrometry-based proteomics is one of the most promising approaches for identifying thousands of phosphorylation events in a single experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12554f89af4b740f8ab81d69a6079e28
https://doi.org/10.1021/acs.jproteome.6b00905
https://doi.org/10.1021/acs.jproteome.6b00905
Autor:
Daniel Mulhern, Radha Uppala, Timothy Riiff, John C. Newman, Bradford W. Gibson, Lei Zhu, Robert Stevens, Wenjuan He, Alexandria K. Sahu, Eric Verdin, Philipp Gut, Matthew P. Jacobson, Yuya Nishida, Christopher B. Newgard, Chris Carrico, Steven R. Danielson, Eric S. Goetzman, Mark Fitch, Marc K. Hellerstein, Biao Li, Ailan Guo, Matthew J. Rardin, Jing Zhou, Olga Ilkayeva
Publikováno v:
Cell metabolism, vol 18, iss 6
SummaryReversible posttranslational modifications are emerging as critical regulators of mitochondrial proteins and metabolism. Here, we use a label-free quantitative proteomic approach to characterize the lysine succinylome in liver mitochondria and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3953d7e3d4a2eb3c49e07d413fdda4
https://europepmc.org/articles/PMC4105152/
https://europepmc.org/articles/PMC4105152/
Autor:
Sean A. Beausoleil, Vicky Yang, Xiaoying Jia, Jon M. Kornhauser, Jeffrey C. Silva, Kimberly Lee, Jianmin Ren, Jing Zhou, Daniel Mulhern, Mike Aguiar, Hongbo Gu, Vidyasiri Vemulapalli, Mark T. Bedford, Michael J. Comb, Ailan Guo, Yi Wang
Publikováno v:
Molecular & Cellular Proteomics : MCP
Protein methylation is a common posttranslational modification that mostly occurs on arginine and lysine residues. Arginine methylation has been reported to regulate RNA processing, gene transcription, DNA damage repair, protein translocation, and si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a964e3fc2d97938479d6d31a9abf0cfc
https://pubmed.ncbi.nlm.nih.gov/24129315
https://pubmed.ncbi.nlm.nih.gov/24129315
Autor:
Anthony Possemato, Yi Wang, Michael J. Comb, Lonning Scott Michael, Sean A. Beausoleil, Caroline Keroack, Ailan Guo, Joan Macneil, Tyler Levy, Klarisa Rikova, Daniel Mulhern, Kimberly Lee, Benjamin Hall, Jian M. Ren
Publikováno v:
Molecular Cancer Therapeutics. 12:B197-B197
Recent genomic-based studies have suggested ovarian cancer is a disease of copy instability, with 63 regions of focal amplification, rather than a disease driven by mutation. However, this analysis has been unable to identify changes in protein expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75603db7a749a177bbf52f442447142b
https://doi.org/10.1158/1535-7163.targ-13-b197
https://doi.org/10.1158/1535-7163.targ-13-b197
Autor:
Yi Wang, Daniel Mulhern, Keri Mroszczyk, Kimberly Lee, Sean A. Beausoleil, Joan MacNeill, Anthony Possemato, Michael J. Comb, Benjamin Hall, Klarisa Rikova, Jian Min Ren, Ailan Guo
Publikováno v:
Molecular Cancer Therapeutics. 12:A94-A94
Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, afflicting nearly 200,000 people in the United States each year. Abnormal ALK is found in about 5% of NSCLC cases, meaning more than 5,000 new patients could benefit from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a1b2180315b5e4abcf5c1ea476ac8b8
https://doi.org/10.1158/1535-7163.targ-13-a94
https://doi.org/10.1158/1535-7163.targ-13-a94
Autor:
Klarisa Rikova, Anthony Possemato, Keri Mroszczyk, Kimberly Lee, Daniel Mulhern, Yi Wang, Benjamin Hall, Sean A. Beausoleil, Jian Min Ren, Ailan Guo, Michael J. Comb
Publikováno v:
Cancer Research. 73:4278-4278
In virtually all epithelial tumors, growth factor receptor activity is deregulated by activated mutations, genomic amplification, and autocrine loops. The dependence of tumor cell survival upon the driving oncogene has been called “oncogene addicti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60b0e93b639621789ef8e989470b2f02
https://doi.org/10.1158/1538-7445.am2013-4278
https://doi.org/10.1158/1538-7445.am2013-4278