Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Daniel Morales Cano"'
Autor:
Kimberley R.G. Cortenbach, Daniel Morales Cano, Jelena Meek, Mark A.J. Gorris, Alexander H.J. Staal, Mangala Srinivas, I. Jolanda M. de Vries, Jacob Fog Bentzon, Roland R.J. van Kimmenade
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 44, Iss , Pp 101111- (2023)
Background: Aim of this study was to investigate immune cells and subsets in different stages of human coronary artery disease with a novel multiplex immunohistochemistry (mIHC) technique. Methods: Human left anterior descending coronary artery speci
Externí odkaz:
https://doaj.org/article/27397b8c5c104c7ab3725aa101aa2d69
Autor:
Sandra Medrano-Garcia, Daniel Morales-Cano, Bianca Barreira, Alba Vera-Zambrano, Rahul Kumar, Djuro Kosanovic, Ralph Theo Schermuly, Brian B. Graham, Francisco Perez-Vizcaino, Alistair Mathie, Rajkumar Savai, Soni Pullamseti, Ghazwan Butrous, Edgar Fernández-Malavé, Angel Cogolludo
Publikováno v:
Cells, Vol 11, Iss 15, p 2414 (2022)
HIV and Schistosoma infections have been individually associated with pulmonary vascular disease. Co-infection with these pathogens is very common in tropical areas, with an estimate of six million people co-infected worldwide. However, the effects o
Externí odkaz:
https://doaj.org/article/ea63a3af06fc4a9ead50b0c65617d7ab
Autor:
María Callejo, Gema Mondejar-Parreño, Bianca Barreira, José L. Izquierdo-Garcia, Daniel Morales-Cano, Sergio Esquivel-Ruiz, Laura Moreno, Ángel Cogolludo, Juan Duarte, Francisco Perez-Vizcaino
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract We have analysed whether pulmonary arterial hypertension (PAH) alters the rat faecal microbiota. Wistar rats were injected with the VEGF receptor antagonist SU5416 (20 mg/kg s.c.) and followed for 2 weeks kept in hypoxia (10% O2, PAH) or inj
Externí odkaz:
https://doaj.org/article/4b82a1856ded4f90ab2d78077a5e9f99
Autor:
Rahul Kumar, Claudia Mickael, Biruk Kassa, Linda Sanders, Dan Koyanagi, Daniel Hernandez‐Saavedra, Scott Freeman, Daniel Morales‐Cano, Angel Cogolludo, Amy S. McKee, Andrew P. Fontenot, Ghazwan Butrous, Rubin M. Tuder, Brian B. Graham
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 15 (2019)
Background Inflammation underlies many forms of pulmonary hypertension (PH), including that resulting from Schistosoma infection, a major cause of PH worldwide. Schistosomiasis‐associated PH is proximately triggered by embolization of parasite eggs
Externí odkaz:
https://doaj.org/article/a6e8e9ca75034f6a817223a5778a472f
Autor:
Daniel Morales-Cano, Maria Callejo, Bianca Barreira, Gema Mondejar-Parreño, Sergio Esquivel-Ruiz, Sonia Ramos, María Ángeles Martín, Angel Cogolludo, Laura Moreno, Francisco Perez-Vizcaino
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211281 (2019)
Diabetes is a very strong predictor of chronic systemic vascular diseases and acute cardiovascular events. Recently, associations between metabolic disorders and pulmonary hypertension have also been reported in both humans and animal models. In orde
Externí odkaz:
https://doaj.org/article/206654d776ce43b58b3fc52b4a633cf6
Autor:
Daniel Morales-Cano, Jose Luis Izquierdo-García, Bianca Barreira, Sergio Esquivel-Ruiz, Maria Callejo, Rachele Pandolfi, Palmira Villa-Valverde, Ignacio Rodríguez, Angel Cogolludo, Jesus Ruiz-Cabello, Francisco Perez-Vizcaino, Laura Moreno
Publikováno v:
Frontiers in Pharmacology. 14
Background: Despite increasing evidence suggesting that pulmonary arterial hypertension (PAH) is a complex disease involving vasoconstriction, thrombosis, inflammation, metabolic dysregulation and vascular proliferation, all the drugs approved for PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0826998e60b7495bbcb3eb7184bfac58
https://doi.org/10.3389/fphar.2023.1021535
https://doi.org/10.3389/fphar.2023.1021535
Autor:
Maria Callejo, Daniel Morales-Cano, Gema Mondejar-Parreño, Bianca Barreira, Sergio Esquivel-Ruiz, Miguel Angel Olivencia, Laura Moreno, Angel Cogolludo, Francisco Perez-Vizcaino
Publikováno v:
Biomolecules, Vol 11, Iss 6, p 795 (2021)
Background: Vitamin D (vitD) deficiency is highly prevalent in patients with pulmonary arterial hypertension (PAH). Moreover, PAH-patients with lower levels of vitD have worse prognosis. We hypothesize that recovering optimal levels of vitD in an ani
Externí odkaz:
https://doaj.org/article/bf589f58ed654b58be33bc7184d98d01
Autor:
Daniel Morales-Cano, Bianca Barreira, Beatriz De Olaiz Navarro, María Callejo, Gema Mondejar-Parreño, Sergio Esquivel-Ruiz, Jose A. Lorente, Laura Moreno, Joan A. Barberá, Ángel Cogolludo, Francisco Perez-Vizcaino
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 155 (2021)
Current approved therapies for pulmonary hypertension (PH) aim to restore the balance between endothelial mediators in the pulmonary circulation. These drugs may exert vasodilator effects on poorly oxygenated vessels. This may lead to the derivation
Externí odkaz:
https://doaj.org/article/27829e363cb446dab0054b648119231b
Autor:
Virginia Chamorro, Daniel Morales-Cano, Javier Milara, Bianca Barreira, Laura Moreno, María Callejo, Gema Mondejar-Parreño, Sergio Esquivel-Ruiz, Julio Cortijo, Ángel Cogolludo, Joan A Barberá, Francisco Perez-Vizcaino
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191239 (2018)
Current treatment with vasodilators for pulmonary hypertension associated with respiratory diseases is limited by their inhibitory effect on hypoxic pulmonary vasoconstriction (HPV) and uncoupling effects on ventilation-perfusion (V'/Q'). Hypoxia is
Externí odkaz:
https://doaj.org/article/2c7850a444eb4281b23240a9aa12e1f2
Autor:
Juan Duarte, Grégoire Manaud, Frédéric Perros, Bianca Barreira, Laura Moreno, Gema Mondejar-Parreño, Daniel Morales-Cano, María Callejo, Sergio Esquivel-Ruiz, Francisco Perez-Vizcaino, Angel Cogolludo, Miguel A Olivencia
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 319:L627-L640
Vitamin D (VitD) receptor regulates the expression of several genes involved in signaling pathways affected in pulmonary hypertension (PH). VitD deficiency is highly prevalent in PH, and low levels are associated with poor prognosis. We investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4afd00390d781ae16ee9a690a2f3076
https://doi.org/10.1152/ajplung.00475.2019
https://doi.org/10.1152/ajplung.00475.2019