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Autor:
Dino Nisato, Jean Wagnon, Claude Plouzane, Vladimir Pliška, Georges Callet, Bernard Tonnerre, Jean Louis Assens, Jean Luc Fauchere, Daniel Mettefeu
Publikováno v:
Journal of medicinal chemistry. 30(12)
Free-Wilson and correlation analysis were combined to study a series of 34 pepstatin analogues in which mainly position 2 was varied. A statistically highly significant correlation was found between the inhibitory activity of the analogues on an enri