Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Daniel Menendez"'
Autor:
PAULA ALMEIDA BRITO, Mariluce Paes De Souza, Daniel Menéndez Llerena, Tomás Daniel Menendez Rodrigues
Publikováno v:
Revista de Gestão e Organizações Cooperativas, Vol 7, Iss 14, Pp 133-150 (2020)
O presente artigo tem como objetivo identificar a motivação para participar em organizações socias do ramo de agroindústria familiar no estado de Rondônia. Parte-se da análise das perspectivas individuais e coletivas, de forma unificada, recon
Externí odkaz:
https://doaj.org/article/3d60b3bb562b4fcf80236e7499aba9fc
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 8, Pp 857-870 (2018)
Breast cancer treatment often includes Doxorubicin as adjuvant as well as neoadjuvant chemotherapy. Despite its cytotoxicity, cells can develop drug resistance to Doxorubicin. Uncovering pathways and mechanisms involved in drug resistance is an urgen
Externí odkaz:
https://doaj.org/article/c5d0740836df4933ae6afba7f1d9b138
Publikováno v:
BioDiscovery, Vol 8, Iss , Pp 1-12 (2013)
The commonly held view of the tumor suppressor p53 as a regulator of cell proliferation, apoptosis and senescence has expanded greatly in recent years to cover many biological processes as well as external and internal stress responses. Since the dis
Externí odkaz:
https://doaj.org/article/4d11fdacf62949aea6339d37b864db23
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155875 (2016)
Determining mechanism-based biomarkers that distinguish adaptive and adverse cellular processes is critical to understanding the health effects of environmental exposures. Shifting from in vivo, low-throughput toxicity studies to high-throughput scre
Externí odkaz:
https://doaj.org/article/d661d7a775e34c2b829511a815d7d02d
Autor:
Daniel Menendez, Maria Shatz, Kathleen Azzam, Stavros Garantziotis, Michael B Fessler, Michael A Resnick
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001360 (2011)
In recent years the functions that the p53 tumor suppressor plays in human biology have been greatly extended beyond "guardian of the genome." Our studies of promoter response element sequences targeted by the p53 master regulatory transcription fact
Externí odkaz:
https://doaj.org/article/1c851161da124fd6ab494edb49d4b45a
Autor:
Yari Ciribilli, Virginia Andreotti, Daniel Menendez, Jan-Stephan Langen, Gilbert Schoenfelder, Michael A Resnick, Alberto Inga
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10236 (2010)
BackgroundRecently, we established that a C>T single nucleotide polymorphism (SNP) in the promoter of the VEGF receptor FLT1 gene generates a (1/2) site p53 response element (RE-T) that results in p53 responsiveness of the promoter. The transcription
Externí odkaz:
https://doaj.org/article/df11313559c046e288d78100b7f01f31
Autor:
Maher A Noureddine, Daniel Menendez, Michelle R Campbell, Omari J Bandele, Monica M Horvath, Xuting Wang, Gary S Pittman, Brian N Chorley, Michael A Resnick, Douglas A Bell
Publikováno v:
PLoS Genetics, Vol 5, Iss 5, p e1000462 (2009)
The p53 tumor suppressor regulates its target genes through sequence-specific binding to DNA response elements (REs). Although numerous p53 REs are established, the thousands more identified by bioinformatics are not easily subjected to comparative f
Externí odkaz:
https://doaj.org/article/c25bbce90e3945b88637a8ae0d552b94
Autor:
Jennifer J. Jordan, Daniel Menendez, Alberto Inga, Maher Nourredine, Douglas Bell, Michael A. Resnick
Publikováno v:
PLoS Genetics, Vol 4, Iss 10 (2008)
Externí odkaz:
https://doaj.org/article/5cd46a7e42a04bc4b685a0a406674090
Autor:
Jennifer J Jordan, Daniel Menendez, Alberto Inga, Maher Noureddine, Douglas A Bell, Michael A Resnick
Publikováno v:
PLoS Genetics, Vol 4, Iss 6, p e1000104 (2008)
Sequence-specific binding by the human p53 master regulator is critical to its tumor suppressor activity in response to environmental stresses. p53 binds as a tetramer to two decameric half-sites separated by 0-13 nucleotides (nt), originally defined
Externí odkaz:
https://doaj.org/article/347cda0bee854685958fc2f6f3fca987
Supplemental material and methods, supplemental tables (1-6) and supplemental figures (1-5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e45ea052487973ed762d0658b3e1b9d
https://doi.org/10.1158/1541-7786.22517539
https://doi.org/10.1158/1541-7786.22517539
