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pro vyhledávání: '"Daniel McNavish"'
Publikováno v:
Circulation. 145
Background: Cannabis is the most widely used illicit substance in the U.S. Observational studies have shown an increased risk of coronary heart disease (CHD). However, little evidence is available describing how duration of cumulative exposure influe
Autor:
Walter Schiffer, David J. R. Taylor, Daniel Soetkamp, Benjamin D. Gould, Jennifer E. Van Eyk, Anna Guzman, Weston R. Spivia, Lin Tan, Heinrich Taegtmeyer, Helen B. Burks, Blake Hanson, Anja Karlstaedt, Heidi Vitrac, Philip L. Lorenzi, Rebecca Salazar, Daniel McNavish, An Q Dinh, Roberta A. Gottlieb, Koen Raedschelders, Stavros Azinas
About 20-30% of cancer-associated deaths are due to complications from cachexia which is characterized by skeletal muscle atrophy. Metabolic reprogramming in cancer cells causes body-wide metabolic and proteomic remodeling, which remain poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de41df7869a7873d19bfadcb5e41a9c
https://doi.org/10.1101/2020.10.13.338202
https://doi.org/10.1101/2020.10.13.338202
Autor:
Roberta A. Gottlieb, Helen B. Burks, Anja Karlstaedt, Rebecca Salazar, Jennifer VanEyk, David J. Taylor, An Dinh, Benjamin D. Gould, Daniel Soetkamp, Walter Schiffer, Blake Hanson, Heinrich Taegtmeyer, Weston R. Spivia, Daniel McNavish, Koen Raedschelders, Heidi Vitrac
Publikováno v:
Circulation Research. 125
Metabolic rewiring is a hallmark of cancer and muscle cells. In isocitrate dehydrogenase 1 and 2 mutant tumors, increased plasma levels of the oncometabolite D-2-hydroxyglutarate (D2-HG) are associated with systemic effects, including myopathy. Our r
Publikováno v:
Circulation. 136
Introduction: The term “cancer and the heart” traditionally refers to the cardiotoxic effects of chemotherapeutic agents. However, independent of any cytostatic treatment cancer survivors have a five-fold higher risk for developing heart failure.