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pro vyhledávání: '"Daniel Mahony"'
Autor:
Emma Lees, Eric Lam, Daniel Mahony, Wei Wei Wu, Yong Jun Liu, Piotr Sicinski, Janet Glassford, Maureen Howard, Gerry G. B. Klaus, Nanette Solvason, Robert A. Weinberg, David A.D. Parry
Publikováno v:
International Immunology. 12:631-638
Progression into G(1) in B lymphocytes is regulated by cyclins D2 and D3, components of the cell cycle machinery currently believed to have overlapping and potentially redundant roles in cell cycle control. To study the specific role of cyclin D2 in
Autor:
Wolfgang Seghezzi, Hiroyuki Kumagai, Hisao Masai, Masayuki Yamada, Daniel Mahony, Ken-ichi Arai, Emma Lees, Noriko Sato
Publikováno v:
Molecular and Cellular Biology. 19:5083-5095
A novel human protein, ASK (activator of S phase kinase), was identified on the basis of its ability to bind to human Cdc7-related kinase (huCdc7). ASK forms an active kinase complex with huCdc7 that is capable of phosphorylating MCM2 protein. ASK ap
Publikováno v:
Molecular and Cellular Biology. 19:1775-1783
The D-type cyclins and their major kinase partners CDK4 and CDK6 regulate G0-G1-S progression by contributing to the phosphorylation and inactivation of the retinoblastoma gene product, pRB. Assembly of active cyclin D-CDK complexes in response to mi
Publikováno v:
Molecular and Cellular Biology. 19:1460-1469
SWI-SNF complexes have been implicated in transcriptional regulation by chromatin remodeling. We have identified an interaction between two components of the mammalian SWI-SNF complex and cyclin E, an essential cell cycle regulatory protein required
Active cdk6 complexes are predominantly nuclear and represent only a minority of the cdk6 in T cells
Publikováno v:
Oncogene. 16:603-611
We have performed biochemical analyses of cdk6 complexes in T cells. By gel filtration chromatography we observed at least three cdk6 containing complexes in the cell, the most abundant eluting at 450 kDa and 50-70 kDa and a minor complex eluting at
Autor:
John B. Gurdon, Daniel Mahony
We have cloned a type I serine/threonine kinase receptor, XTrR-I, from Xenopus. XTrR-I (Xenopus transforming growth factor beta-related receptor type I) is expressed in all regions of embryos throughout early development. Overexpression of this recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643e5b04b0c46c41b99a9de38b4f6aef
https://europepmc.org/articles/PMC41540/
https://europepmc.org/articles/PMC41540/
Autor:
Wolfgang Seghezzi, Frances Shanahan, Daniel Mahony, Emma Lees, David A.D. Parry, Wouter Korver, Claudia Guevara
Publikováno v:
Kidney International. 56:1182
The entry of a cell into DNA synthesis is a critical entry, but the way in which this enzyme promotes DNA synthesis is poorly understood because few substrates regulation point for all living cells. A number of cyclins have been identified. We are cu
Publikováno v:
Human Development. 19:1-13
The paper examines structural paradigms for the analysis of narrative drawn from Levi-Strauss, Propp and Piaget. It shows that all are successful in differentiating between the stories freely told by children of different age levels ranging from 2 to