Bone Injury and Repair Trigger Central and Peripheral NPY Neuronal Pathways.

Autor: Cecília J Alves, Inês S Alencastre, Estrela Neto, João Ribas, Sofia Ferreira, Daniel M Vasconcelos, Daniela M Sousa, Teresa Summavielle, Meriem Lamghari

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0165465 (2016)

Bone repair is a specialized type of wound repair controlled by complex multi-factorial events. The nervous system is recognized as one of the key regulators of bone mass, thereby suggesting a role for neuronal pathways in bone homeostasis. However,

Externí odkaz: https://doaj.org/article/4806ba10bc9547e1827da5de5dd2fe79

Profiling the circulating miRnome reveals a temporal regulation of the bone injury response

Autor: Carla Cunha, José H. Teixeira, Susana G. Santos, Daniel M. Vasconcelos, George A. Calin, Mário A. Barbosa, Joana Oliveira, Cristina Ivan, Maria Inês Almeida, Nuno Neves, Cláudia Ribeiro-Machado, Andreia M. Silva

Publikováno v: Theranostics
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Bone injury healing is an orchestrated process that starts with an inflammatory phase followed by repair and remodelling of the bone defect. The initial inflammation is characterized by local changes in immune cell populations and molecular mediators

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73c1be66f9f934aa36281c5cbe07024
http://europepmc.org/articles/PMC6071520

Interplay between sympathetic nervous system and inflammation in aseptic loosening of hip joint replacement

Autor: Rui Henrique, Nuno Neves, Maria José Oliveira, Gilberto Costa, Meriem Lamghari, Daniel M. Vasconcelos, Inês S. Alencastre, Cecília J. Alves, M. Ribeiro-da-Silva, Daniela Linhares

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Inflammation is a common symptom in joint disorders such as rheumatoid arthritis, osteoarthritis (OA) and implant aseptic loosening (AL). The sympathetic nervous system is well known to play a critical role in regulating inflammatory conditions, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465dfd2a028d0416a0e20ac3ed060c25
https://doi.org/10.1038/s41598-018-33360-8

Neuroimmune expression in hip osteoarthritis: a systematic review

Autor: Daniel M. Vasconcelos, Manuel A.V. Ribeiro da Silva, Nuno Neves, Meriem Lamghari, Gilberto Costa, Cecília J. Alves, Daniela Linhares

Publikováno v: BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders, Vol 18, Iss 1, Pp 1-11 (2017)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Background Neuroimmune axis is central in the physiopathology of hip osteoarthritis (OA), but its specific pathways are still unclear. This systematic review aims to assess the nervous and immune system profile of patients with hip osteoarthritis (OA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f02320f677632d5f875a1719b9d0300
https://doi.org/10.1186/s12891-017-1755-2

Technical Standards and Legislation for Implants and Implantable Medical Devices

Autor: J. Cortez, Daniel M. Vasconcelos, Meriem Lamghari

Advances in medical devices have had a clear impact on the level and quality of healthcare provided worldwide, as well as on patients’ quality of life and life expectancy. A wide range of medical devices have been developed in past decades, creatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dde554c4ea79b96f9ff92c381994473e
https://doi.org/10.1016/b978-0-12-803581-8.04059-5