Výsledky vyhledávání - "Daniel M. Staren"

The CXC Chemokine Receptor 4 Ligands Ubiquitin and Stromal Cell-derived Factor-1α Function through Distinct Receptor Interactions

Autor: Vikas Saini, Joshua J. Ziarek, Edward M. Campbell, Adriano Marchese, Matthias Majetschak, Brian F. Volkman, Zayd N. Nashaat, Daniel M. Staren

Publikováno v: Journal of Biological Chemistry. 286:33466-33477

Recently, we identified extracellular ubiquitin as an endogenous CXC chemokine receptor (CXCR) 4 agonist. However, the receptor selectivity and molecular basis of the CXCR4 agonist activity of ubiquitin are unknown, and functional consequences of CXC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83274d29489da672e055bb0ada9976c4
https://doi.org/10.1074/jbc.m111.233742

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CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1α and ubiquitin

Autor: Daniel M. Staren, Abhishek Tripathi, Jeffrey D. Davis, Brian F. Volkman, Matthias Majetschak

Publikováno v: Cytokine. 65(2)

Recently, we reported that extracellular ubiquitin functions as another agonist of CXC chemokine receptor (CXCR)4. Whereas the cognate CXCR4 ligand, stromal cell-derived factor (SDF)-1α, is also a CXCR7 agonist, ubiquitin does not bind to CXCR7. Bec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4404126fcb214fcfd8ea05dede014f7
https://pubmed.ncbi.nlm.nih.gov/24373940

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