Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Daniel M. Solomon"'
Autor:
William Lynders, Syed A. Jamal Bokhari, Michael Crain, Michael P. Goldman, Daniel M. Solomon, Gunjan Tiyyagura, Beth L. Emerson, Marc Auerbach, Mariann Nocera Kelley
Publikováno v:
Pediatric Quality & Safety
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Introduction: The primary aim of this quality improvement initiative was to decrease the use of computerized tomography (CT) in the evaluation of pediatric appendicitis in a community genera
Introduction: The primary aim of this quality improvement initiative was to decrease the use of computerized tomography (CT) in the evaluation of pediatric appendicitis in a community genera
Autor:
Rema Bitar, John C. Anthes, Jonathan E. Phillips, Purakkattle Biju, Robert G. Aslanian, Aileen House, Michael Berlin, Stephen Eckel, Daniel M. Solomon, George Kelly, Robbie L. McLeod, Richard Chapman, Xiomara Fernandez, Michelle Natiello, Daniel Prelusky, Kevin D. McCormick
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6343-6347
A series of C-21 mercapto derivatives of hydrocortisone have been synthesized and evaluated in cell based transrepression and transactivation assays. The benzothiazole derivative, compound 6 not only showed a dissociated profile in vitro functional a
Autor:
Neng-Yang Shih, Robert E. West, Robert G. Aslanian, Daniel M. Solomon, Wing C. Tom, Pauline C. Ting, Joe F. Lee, Margaret M. Albanese
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:2643-2646
A novel non-imidazole fluorene oxime 1a has been identified as a histamine H 3 inhibitor, and its structure–activity relationship has been evaluated.
Autor:
Daniel M. Solomon, Pauline C. Ting, Sidney R. Smith, Demetris N. Zambas, James Jakway, Carol Terminelli, Joe F. Lee
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2749-2754
2-[10,11-Dihydro-5-ethoxy-5 H -dibenzo[a,d]cyclohepten-5-yl]-N,N-dimethyl-ethanamine (1) has been found to possess anticytokine activity. The synthesis and structure-activity relationship study of a series of analogues are reported.
Autor:
Daniel M. Solomon, Pauline C. Ting
Publikováno v:
Journal of Heterocyclic Chemistry. 32:1027-1032
A synthesis of novel spiro[4′,5′,10,11-tetrahydro-5H-dibenzo[a,d]cyclohepten-5-yl-2′(3′H)-furans] is described. The key reaction was formation of the tetrahydrofuran ring by cyclization of the diol 3 or the protected diol 10. These compounds
Autor:
Jonathan E. Phillips, Yanlin Jia, Gissela Lieber, Daniel Prelusky, Rema Bitar, Stephen Eckel, George Kelly, Purakkattle Biju, Michael Berlin, Johanna Jimenez, Richard Chapman, John C. Anthes, Hongwu Wang, Robbie L. McLeod, Daniel M. Solomon, Aileen House, Yoon Joo Lee, X. Fernandez, Robert G. Aslanian, Kevin D. McCormick
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(2)
The prednisolone C-21 heteroaryl thioethers have been synthesized and evaluated in cell based transrepression and transactivation assays. Most of the compounds demonstrated weak transactivational activity in both human and rat tyrosineaminotransferas
Autor:
Daniel M. Solomon, Pauline C. Ting
Publikováno v:
ChemInform. 26
A synthesis of novel spiro[4′,5′,10,11-tetrahydro-5H-dibenzo[a,d]cyclohepten-5-yl-2′(3′H)-furans] is described. The key reaction was formation of the tetrahydrofuran ring by cyclization of the diol 3 or the protected diol 10. These compounds
Autor:
Matthew Bryant, Maria A. Rivelli, Luli Duguma, Joe F. Lee, Michel R. Corboz, Neng-Yang Shih, Leonard Favreau, Robert E. West, Ren-Long Wu, Robert G. Aslanian, H. Susan She, Margaret M. Albanese, Mccormick Kevin D, Mwangi W. Mutahi, Wayne D. Vaccaro, Michael Y. Berlin, Pauline C. Ting, John A. Hey, Wei Zhou, Rosy Sher, Walter A. Korfmacher, Cymbelene Nardo, John C. Anthes, Piwinski John J, Daniel M. Solomon, Shirley M. Williams
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(4)
A novel series of histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine template displaying low CYP2D6 and CYP3A4 inhibitory profiles has been identified. Structural features responsible for the reduction of P450 activ
Autor:
Mccormick Kevin D, Mwangi W. Mutahi, Maria A. Rivelli, H. Susan She, Michel R. Corboz, Leonard Favreau, Pauline C. Ting, Wayne D. Vaccaro, Wei Zhou, Cymbelene Nardo, Neng-Yang Shih, Robert E. West, Shirley M. Williams, Margaret M. Albanese, Ren-Long Wu, Matthew Bryant, John A. Hey, Luli Duguma, Walter A. Korfmacher, Joe F. Lee, Piwinski John J, John C. Anthes, Daniel M. Solomon, Rosy Sher, Michael Y. Berlin, Robert G. Aslanian
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:3342
Autor:
Priya Aarthy, Archunan1,2 (AUTHOR) aarthyarchun94@gmail.com, Sen, Sangeetha1 (AUTHOR), Srinivasan, Mahalingam3 (AUTHOR), Muthukumar, Subramanian4 (AUTHOR) sasmuthu@gmail.com, Madhanraj, Pakirisamy5 (AUTHOR), Akbarsha, Mohammad Abdulkader6,7 (AUTHOR), Archunan, Govindaraju3,8 (AUTHOR) garchu56@yahoo.co.in
Publikováno v:
Scientific Reports. 10/6/2023, Vol. 13 Issue 1, p1-14. 14p.