Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Daniel M. Messerschmidt"'
Autor:
Michael Claxton, Michela Pulix, Michelle K. Y. Seah, Ralph Bernardo, Peng Zhou, Sultan Aljuraysi, Triantafillos Liloglou, Philippe Arnaud, Gavin Kelsey, Daniel M. Messerschmidt, Antonius Plagge
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Genomic imprinting is an epigenetic process through which genes are expressed in a parent-of-origin specific manner resulting in mono-allelic or strongly biased expression of one allele. For some genes, imprinted expression may be tissue-specific and
Externí odkaz:
https://doaj.org/article/200af60483434345a909d8f1a1f9d8dd
Autor:
Brenda Y. Han, Michelle K. Y. Seah, Imogen R. Brooks, Delia H. P. Quek, Dominic R. Huxley, Chuan-Sheng Foo, Li Ting Lee, Heike Wollmann, Huili Guo, Daniel M. Messerschmidt, Ernesto Guccione
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.
Externí odkaz:
https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b3
Publikováno v:
Stem cell reports, 14(5), 818-827. Cell Press
Stem Cell Reports
Stem Cell Reports
Summary Spermatogenesis relies on exquisite stem cell homeostasis, the carefully balanced self-renewal and differentiation of spermatogonial stem cells (SSCs). Disturbing this equilibrium will likely manifest through sub- or infertility, a global hea
Autor:
Elisabeth Pfeiffenberger, Chandrahas Koumar Ratnacaram, Ernesto Guccione, Joel Heng Loong Tan, Radoslaw M. Sobota, Xavier Bisteau, Daniel M. Messerschmidt, Heike Wollmann, Philipp Kaldis, Jayantha Gunaratne, Sheena Wee, Joanna H.S. Lee, Diana Low, Nathan Palmer, S. Zakiah A. Talib
Publikováno v:
The Journal of cell biology, 218 (9
The Journal of Cell Biology
The Journal of Cell Biology
Palmer et al. identify NRF1 as a novel CDK2 interactor and substrate. This interaction was found to be important for the DNA-binding activity of NRF1. Their findings demonstrate that the loss of CDK2 expression impairs the regulation of NRF1 transcri
Autor:
Daniel M. Messerschmidt, Sam Tan Jian Chye, Marie van Dijk, Gijs B. Afink, Souad Boussata, Barbara B. Knowles, Ling Ka Yi, Chin Yan Lim, Serene C Chng, Lena Ho, Grace H. Goh, Bruno Reversade, Davor Solter, N. Ray Dunn, Sheena Ong
Publikováno v:
Science, 357(6352), 707-713. American Association for the Advancement of Science
Ho, L, Van Dijk, M, Chye, S T J, Messerschmidt, D M, Chng, S C, Ong, S, Yi, L K, Boussata, S, Goh, G H Y, Afink, G B, Lim, C Y, Dunn, N R, Solter, D, Knowles, B B & Reversade, B 2017, ' ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice ', Science, vol. 357, no. 6352, pp. 707-713 . https://doi.org/10.1126/science.aam6607
Ho, L, Van Dijk, M, Chye, S T J, Messerschmidt, D M, Chng, S C, Ong, S, Yi, L K, Boussata, S, Goh, G H Y, Afink, G B, Lim, C Y, Dunn, N R, Solter, D, Knowles, B B & Reversade, B 2017, ' ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice ', Science, vol. 357, no. 6352, pp. 707-713 . https://doi.org/10.1126/science.aam6607
Modeling a pregnancy disorder Preeclampsia, a dangerous pregnancy disorder marked by high blood pressure, can lead to premature birth and be life-threatening to the mother and baby. Research leading to effective treatments has been hampered by a lack
Autor:
Delphine Hequet, N. Ray Dunn, Colin L. Stewart, Yuin-Han Loh, Jingxian Zhang, Heike Wollmann, Haitong Fang, Vinay Tergaonkar, Ernesto Guccione, Daniel M. Messerschmidt, Slim Mzoughi, Michelle K. Y. Seah, Qiao Rui Xing, Eun Myoung Shin, Sheena Li Ming Ong, Shun Xie Teo, Esther Sook Miin Wong, Marco Bezzi, Muthafar Al-Haddawi
Publikováno v:
Nature Genetics. 49:1354-1363
Ernesto Guccione and colleagues report that the transcription factor PRDM15 regulates naive pluripotency in mouse embryos and embryonic stem cells and in derivation of mouse and human iPSCs. They further show that PRDM15 promotes WNT signaling and in
Autor:
Yaju Wang, Hui Mun Loh, Slim Mzoughi, Michelle K. Y. Seah, Wen Jun Peh, Gernot Wolf, Heike Wollmann, Brenda Y. Han, Esther Sook Miin Wong, Diana Low, Pierre-Alexis Goy, Ernesto Guccione, Ei Leen Leong, Daniel M. Messerschmidt, Todd S. Macfarlan
Publikováno v:
Development (Cambridge, England)
Global epigenetic reprogramming is vital to purge germ cell-specific epigenetic features to establish the totipotent state of the embryo. This process transpires to be carefully regulated and is not an undirected, radical erasure of parental epigenom
Autor:
Barbara B. Knowles, Wilhelmine N. de Vries, Davor Solter, Sathish Balu, Chanchao Lorthongpanich, Daniel M. Messerschmidt
Publikováno v:
Development. 143:1993-1999
β-catenin (CTNNB1) is integral to cell adhesion and to the canonical Wnt signaling pathway. The effects of maternal and zygotic CTNNB1 on embryogenesis have each been separately assessed, whereas the effect of its total absence has not. As the ‘tr
Publikováno v:
Current topics in developmental biology. 128
When reflecting about cell fate commitment we think of differentiation. Be it during embryonic development or in an adult stem cell niche, where cells of a higher potency specialize and cell fate decisions are taken. Under normal circumstances this p
When reflecting about cell fate commitment we think of differentiation. Be it during embryonic development or in an adult stem cell niche, where cells of a higher potency specialize and cell fate decisions are taken. Under normal circumstances this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5af60b9f6968c88d0c12a4264aa8f24
https://doi.org/10.1016/bs.ctdb.2017.10.011
https://doi.org/10.1016/bs.ctdb.2017.10.011