Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel M. Bollag"'
Publikováno v:
Journal of Natural Products. 57:1670-1674
Chemical investigation of the cytotoxic fraction of Koelreuteria henryi resulted in the isolation of three cyclolignans. A new cyclolignan, named koelreuterin-1 was elucidated as furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(8H)-one,5-(7-methoxy-1, 3- b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1268adc90fa6a18586bfb3e7c183e7
https://doi.org/10.1021/np50114a008
https://doi.org/10.1021/np50114a008
Autor:
Daniel M. Bollag
Publikováno v:
Expert opinion on investigational drugs. 6(7)
The past few years have witnessed the regulatory approvals of the anticancer microtubule stabilising taxane drugs, Taxol and Taxotere, which are rapidly gaining acceptance as important antineoplastic agents with potential against numerous solid tumou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7b4cc8c5da40f83fe41a1b51424ff4
https://pubmed.ncbi.nlm.nih.gov/15989649
https://pubmed.ncbi.nlm.nih.gov/15989649
BACKGROUND: At therapeutic concentrations, the antineoplastic agent taxol selectively perturbs mitotic spindle microtubules. Taxol has recently been shown to induce apoptosis, similar to the mechanism of cell death induced by other antineoplastic age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b0476f02d0b04005078278c4116dc5
https://europepmc.org/articles/PMC2229961/
https://europepmc.org/articles/PMC2229961/
Publikováno v:
Springer Series in Biophysics ISBN: 9783642739279
Microtubules, cytoskeletal organelles composed of αβ tubulin heterodimers, are implicated in a wide variety of cell functions including nuclear division, intracellular transport and cell motility (Dustin, 1984). Neither the specific roles nor the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c9d95742a88d95d378a8f5f1cf77e09
https://doi.org/10.1007/978-3-642-73925-5_1
https://doi.org/10.1007/978-3-642-73925-5_1